{"id":7881,"date":"2026-10-09T06:47:03","date_gmt":"2026-10-08T21:47:03","guid":{"rendered":"https:\/\/www.takeuchi-iin.jp\/blog\/?p=7881"},"modified":"2026-10-09T06:47:04","modified_gmt":"2026-10-08T21:47:04","slug":"thiazolidinedione-imeglimin-guide-2026","status":"publish","type":"post","link":"https:\/\/www.takeuchi-iin.jp\/blog\/thiazolidinedione-imeglimin-guide-2026\/","title":{"rendered":"\u30102026\u5e74\u79cb\u3011\u30c1\u30a2\u30be\u30ea\u30b8\u30f3\u85ac\uff08\u30d4\u30aa\u30b0\u30ea\u30bf\u30be\u30f3\uff09\u30fb\u30a4\u30e1\u30b0\u30ea\u30df\u30f3\uff08\u30c4\u30a4\u30df\u30fc\u30b0\uff09\u3092\u98f2\u3093\u3067\u3044\u308b\u65b9\u3078\uff5c\u201c\u30a4\u30f3\u30b9\u30ea\u30f3\u306e\u52b9\u304d\u306b\u304f\u3055\u201d\u3092\u6539\u5584\u3059\u308b\u4ed5\u7d44\u307f\u30fb\u3080\u304f\u307f\u3068\u5fc3\u4e0d\u5168\u30fb\u9aa8\u6298\u306e\u6ce8\u610f\u70b9\u3092\u9662\u9577\u30fb\u4e94\u85e4\u826f\u5c06\u304c\u3084\u3055\u3057\u304f\u89e3\u8aac\u3010\u7530\u5712\u8abf\u5e03\u30fb\u591a\u6469\u5ddd\u3011"},"content":{"rendered":"

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\n \"\u4e94\u85e4<\/p>\n

THIS ARTICLE IS WRITTEN AND SUPERVISED BY<\/p>\n

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<\/div>\n<\/div>\n
\n

\u76ee\u6b21<\/p>\n

    \n
  1. \u300c\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u300d\u3068\u306f\uff1f\u81ea\u5206\u306e\u30bf\u30a4\u30d7\u3092\u77e5\u308b<\/a><\/li>\n
  2. \u30c1\u30a2\u30be\u30ea\u30b8\u30f3\u85ac\uff08\u30d4\u30aa\u30b0\u30ea\u30bf\u30be\u30f3\uff09\u306e\u4ed5\u7d44\u307f\u3068\u7279\u5fb4<\/a><\/li>\n
  3. \u30d4\u30aa\u30b0\u30ea\u30bf\u30be\u30f3\u3067\u6ce8\u610f\u3057\u305f\u3044\u300c\u3080\u304f\u307f\u30fb\u5fc3\u4e0d\u5168\u30fb\u9aa8\u6298\u30fb\u8180\u80f1\u300d<\/a><\/li>\n
  4. \u30a4\u30e1\u30b0\u30ea\u30df\u30f3\uff08\u30c4\u30a4\u30df\u30fc\u30b0\uff09\u306e\u4ed5\u7d44\u307f\u3068\u7279\u5fb4<\/a><\/li>\n
  5. 2\u3064\u306e\u304a\u85ac\u306e\u6bd4\u8f03\u3068\u3001\u5916\u6765\u3067\u3088\u304f\u51fa\u4f1a\u3046\u30b1\u30fc\u30b9<\/a><\/li>\n
  6. \u670d\u7528\u4e2d\u306e\u65b9\u3078\u306e\u304a\u9858\u3044\u30fb\u53d7\u8a3a\u306e\u76ee\u5b89<\/a><\/li>\n
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  8. \u95a2\u9023\u8a18\u4e8b<\/a><\/li>\n
  9. \u53c2\u8003\u6587\u732e<\/a><\/li>\n<\/ol>\n<\/div>\n

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    \n

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    \u4eca\u56de\u3054\u7d39\u4ecb\u3059\u308b2\u3064\u306e\u304a\u85ac\u306f\u3001\u3069\u3061\u3089\u3082\u300c\u30a4\u30f3\u30b9\u30ea\u30f3\u306e\u52b9\u304d\u306b\u304f\u3055\u300d\u306e\u6539\u5584<\/strong>\u306b\u95a2\u308f\u308b\u304a\u85ac\u3067\u3059\u304c\u3001\u4f5c\u7528\u3059\u308b\u5834\u6240\u3084\u6ce8\u610f\u70b9\u306f\u304b\u306a\u308a\u7570\u306a\u308a\u307e\u3059\u3002\u9806\u756a\u306b\u898b\u3066\u307e\u3044\u308a\u307e\u3057\u3087\u3046\u3002<\/p>\n

    \u30c1\u30a2\u30be\u30ea\u30b8\u30f3\u85ac\uff08\u30d4\u30aa\u30b0\u30ea\u30bf\u30be\u30f3\uff09\u306e\u4ed5\u7d44\u307f\u3068\u7279\u5fb4<\/h2>\n

    \u30c1\u30a2\u30be\u30ea\u30b8\u30f3\u85ac\u306f\u3001\u73fe\u5728\u65e5\u672c\u3067\u306f\u30d4\u30aa\u30b0\u30ea\u30bf\u30be\u30f3\uff08\u5148\u767a\u54c1\u540d\uff1a\u30a2\u30af\u30c8\u30b9\u3001\u307b\u304b\u5f8c\u767a\u54c1\uff09<\/strong>\u304c\u4f7f\u308f\u308c\u3066\u3044\u307e\u3059\u3002\u30e1\u30c8\u30db\u30eb\u30df\u30f3\u3084\u03b1-\u30b0\u30eb\u30b3\u30b7\u30c0\u30fc\u30bc\u963b\u5bb3\u85ac\u3068\u306e\u914d\u5408\u9320\u3082\u3042\u308a\u307e\u3059\u3002\u4e3b\u306b\u8102\u80aa\u7d30\u80de<\/strong>\u306b\u50cd\u304d\u304b\u3051\u3066\u3001\u5168\u8eab\u306e\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u3092\u6539\u5584\u3059\u308b\u304a\u85ac\u3067\u3059\u3002<\/p>\n

    \n

    \u30e1\u30ab\u30cb\u30ba\u30e0\u56f3\u89e3\uff5c\u30d4\u30aa\u30b0\u30ea\u30bf\u30be\u30f3\u304c\u8840\u7cd6\u3092\u4e0b\u3052\u308b\u307e\u3067<\/p>\n\n\n\n\n\n
    1<\/text><\/svg><\/td>\nPPAR\u03b3\u3092\u6d3b\u6027\u5316<\/strong>\uff1a\u8102\u80aa\u7d30\u80de\u306e\u6838\u306b\u3042\u308b\u30b9\u30a4\u30c3\u30c1\u300cPPAR\u03b3\uff08\u30d4\u30fc\u30d1\u30fc\u30fb\u30ac\u30f3\u30de\uff09\u300d\u3092\u30aa\u30f3\u306b\u3057\u307e\u3059\u3002<\/td>\n<\/tr>\n
    2<\/text><\/svg><\/td>\n\u8102\u80aa\u7d30\u80de\u304c\u300c\u5c0f\u578b\u3067\u5584\u7389\u300d\u306b<\/strong>\uff1a\u80a5\u5927\u3057\u3066\u60aa\u7389\u7269\u8cea\uff08TNF-\u03b1\u3084\u904a\u96e2\u8102\u80aa\u9178\u306a\u3069\uff09\u3092\u51fa\u3057\u3066\u3044\u305f\u8102\u80aa\u7d30\u80de\u304c\u3001\u5c0f\u578b\u306e\u8102\u80aa\u7d30\u80de\u306b\u7f6e\u304d\u63db\u308f\u308a\u3001\u5584\u7389\u30db\u30eb\u30e2\u30f3\u30a2\u30c7\u30a3\u30dd\u30cd\u30af\u30c1\u30f3<\/strong>\u304c\u5897\u3048\u307e\u3059\u3002<\/td>\n<\/tr>\n
    3<\/text><\/svg><\/td>\n\u809d\u81d3\u30fb\u7b4b\u8089\u306e\u30a4\u30f3\u30b9\u30ea\u30f3\u306e\u52b9\u304d\u304c\u56de\u5fa9<\/strong>\uff1a\u809d\u81d3\u304b\u3089\u306e\u7cd6\u306e\u653e\u51fa\u304c\u6291\u3048\u3089\u308c\u3001\u7b4b\u8089\u3078\u306e\u30d6\u30c9\u30a6\u7cd6\u306e\u53d6\u308a\u8fbc\u307f\u304c\u5897\u3048\u307e\u3059\u3002<\/td>\n<\/tr>\n
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    \n

    \u7528\u8a9e\u89e3\u8aac\uff5cPPAR\u03b3\uff08\u30d4\u30fc\u30d1\u30fc\u30fb\u30ac\u30f3\u30de\uff09\u30fb\u30a2\u30c7\u30a3\u30dd\u30cd\u30af\u30c1\u30f3\u3068\u306f<\/p>\n

    PPAR\u03b3\uff08\u30da\u30eb\u30aa\u30ad\u30b7\u30bd\u30fc\u30e0\u5897\u6b96\u56e0\u5b50\u6d3b\u6027\u5316\u53d7\u5bb9\u4f53\u03b3\uff09\uff1a<\/strong>\u7d30\u80de\u306e\u6838\u306e\u4e2d\u3067\u3001\u3069\u306e\u907a\u4f1d\u5b50\u3092\u50cd\u304b\u305b\u308b\u304b\u3092\u6c7a\u3081\u308b\u300c\u8ee2\u5199\u56e0\u5b50\u300d\u306e\u4e00\u3064\u3067\u3059\u3002\u7279\u306b\u8102\u80aa\u7d30\u80de\u306b\u591a\u304f\u3001\u8102\u80aa\u7d30\u80de\u306e\u6210\u719f\u3084\u8102\u8cea\u30fb\u7cd6\u306e\u4ee3\u8b1d\u3092\u8abf\u7bc0\u3057\u3066\u3044\u307e\u3059\u3002\u30d4\u30aa\u30b0\u30ea\u30bf\u30be\u30f3\u306f\u3053\u306ePPAR\u03b3\u306b\u7d50\u5408\u3057\u3066\u30b9\u30a4\u30c3\u30c1\u3092\u5165\u308c\u308b\u300c\u4f5c\u52d5\u85ac\uff08\u30a2\u30b4\u30cb\u30b9\u30c8\uff09\u300d\u3067\u3059\u3002<\/p>\n

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    \u6dfb\u4ed8\u6587\u66f8\u4e0a\u306e\u4f7f\u3044\u65b9<\/h3>\n\n\n\n\n\n\n\n\n
    \u9805\u76ee<\/th>\n\u5185\u5bb9\uff08\u30d4\u30aa\u30b0\u30ea\u30bf\u30be\u30f3\uff09<\/th>\n<\/tr>\n<\/thead>\n
    \u5bfe\u8c61<\/strong><\/td>\n2\u578b\u7cd6\u5c3f\u75c5\u3067\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u304c\u63a8\u5b9a\u3055\u308c\u308b<\/strong>\u5834\u5408\u306b\u9650\u308b\u3002\u76ee\u5b89\u306fBMI 24\u4ee5\u4e0a<\/strong>\u3001\u307e\u305f\u306f\u7a7a\u8179\u6642\u8840\u4e2d\u30a4\u30f3\u30b9\u30ea\u30f3\u5024 5\u03bcU\/mL\u4ee5\u4e0a<\/strong><\/td>\n<\/tr>\n
    \u7528\u91cf<\/strong><\/td>\n1\u65e51\u56de15\u301c30mg\uff08\u671d\u98df\u524d\u307e\u305f\u306f\u671d\u98df\u5f8c\uff09\u3001\u6700\u592745mg<\/td>\n<\/tr>\n
    \u5c11\u91cf\u304b\u3089\u59cb\u3081\u308b\u65b9<\/strong><\/td>\n\u5973\u6027\u30fb\u9ad8\u9f62\u306e\u65b9\u306f1\u65e515mg\u304b\u3089<\/strong>\u304c\u671b\u307e\u3057\u3044\uff08\u5973\u6027\u306f\u3080\u304f\u307f\u304c\u51fa\u3084\u3059\u3044\u305f\u3081\uff09\u3002\u30a4\u30f3\u30b9\u30ea\u30f3\u3068\u4f75\u7528\u3059\u308b\u5834\u5408\u306f15mg\u304b\u3089\u958b\u59cb\u3057\u3001\u4e0a\u965030mg<\/strong><\/td>\n<\/tr>\n
    \u4f7f\u3048\u306a\u3044\u65b9\uff08\u7981\u5fcc\uff09<\/strong><\/td>\n\u5fc3\u4e0d\u5168\u306e\u65b9\u30fb\u5fc3\u4e0d\u5168\u306e\u65e2\u5f80\u304c\u3042\u308b\u65b9<\/strong>\u3001\u91cd\u7be4\u306a\u809d\u30fb\u814e\u6a5f\u80fd\u969c\u5bb3\u3001\u598a\u5a20\u4e2d\u307e\u305f\u306f\u598a\u5a20\u306e\u53ef\u80fd\u6027\u304c\u3042\u308b\u65b9\u30011\u578b\u7cd6\u5c3f\u75c5\u3001\u91cd\u75c7\u30b1\u30c8\u30fc\u30b7\u30b9 \u306a\u3069<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

    \u671f\u5f85\u3067\u304d\u308b\u3053\u3068<\/h3>\n

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    \u30d4\u30aa\u30b0\u30ea\u30bf\u30be\u30f3\u3067\u6ce8\u610f\u3057\u305f\u3044\u300c\u3080\u304f\u307f\u30fb\u5fc3\u4e0d\u5168\u30fb\u9aa8\u6298\u30fb\u8180\u80f1\u300d<\/h2>\n

    \u30d4\u30aa\u30b0\u30ea\u30bf\u30be\u30f3\u306f\u52b9\u679c\u304c\u306f\u3063\u304d\u308a\u3057\u3066\u3044\u308b\u53cd\u9762\u3001\u7279\u5fb4\u7684\u306a\u526f\u4f5c\u7528<\/strong>\u304c\u3042\u308a\u307e\u3059\u3002\u5b89\u5168\u306b\u304a\u4f7f\u3044\u3044\u305f\u3060\u304f\u305f\u3081\u306b\u3001\u6b21\u306e4\u70b9\u3092\u305c\u3072\u899a\u3048\u3066\u304a\u3044\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n\n\n\n\n\n\n\n\n
    \u6ce8\u610f\u70b9<\/th>\n\u5185\u5bb9<\/th>\n\u3053\u3093\u306a\u3068\u304d\u306f\u3054\u9023\u7d61\u3092<\/th>\n<\/tr>\n<\/thead>\n
    \u3080\u304f\u307f\u30fb\u4f53\u91cd\u5897\u52a0<\/strong><\/td>\n\u814e\u81d3\u3067\u30ca\u30c8\u30ea\u30a6\u30e0\uff08\u5869\u5206\uff09\u3068\u6c34\u5206\u306e\u518d\u5438\u53ce\u304c\u5897\u3048\u3001\u4f53\u6db2\u8caf\u7559<\/strong>\u304c\u8d77\u3053\u308a\u307e\u3059\u3002\u6dfb\u4ed8\u6587\u66f8\u4e0a\u306e\u6d6e\u816b\u306e\u983b\u5ea6\u306f8.2%<\/strong>\u3002\u5973\u6027\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u4f75\u7528\u6642\u300130mg\u304b\u308945mg\u3078\u5897\u91cf\u3057\u305f\u5f8c\u306b\u51fa\u3084\u3059\u3044\u3068\u3055\u308c\u3066\u3044\u307e\u3059<\/td>\n\u3059\u306d\u3092\u62bc\u3059\u3068\u8de1\u304c\u6b8b\u308b\u3001\u9774\u4e0b\u306e\u8de1\u304c\u304f\u3063\u304d\u308a\u30011\u9031\u9593\u30672kg\u4ee5\u4e0a<\/strong>\u306e\u4f53\u91cd\u5897\u52a0<\/td>\n<\/tr>\n
    \u5fc3\u4e0d\u5168<\/strong><\/td>\n\u4f53\u6db2\u8caf\u7559\u306b\u3088\u308a\u3001\u5fc3\u4e0d\u5168\u3092\u767a\u75c7\u30fb\u60aa\u5316\u3055\u305b\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u305d\u306e\u305f\u3081\u5fc3\u4e0d\u5168\u306e\u65b9\u306b\u306f\u4f7f\u3048\u307e\u305b\u3093<\/strong>\uff08\u30a2\u30eb\u30b4\u30ea\u30ba\u30e0\u3067\u3082\u5fc3\u4e0d\u5168\u5408\u4f75\u8005\u3067\u306f\u30d3\u30b0\u30a2\u30ca\u30a4\u30c9\u85ac\u3068\u3068\u3082\u306b\u907f\u3051\u308b\u3068\u660e\u8a18\uff09\u3002\u5b9a\u671f\u7684\u306a\u5fc3\u96fb\u56f3\u306a\u3069\u3067\u78ba\u8a8d\u3057\u307e\u3059<\/td>\n\u968e\u6bb5\u3067\u606f\u5207\u308c\u3001\u6a2a\u306b\u306a\u308b\u3068\u606f\u82e6\u3057\u3044\u3001\u591c\u9593\u306e\u305b\u304d<\/td>\n<\/tr>\n
    \u9aa8\u6298<\/strong><\/td>\n\u6d77\u5916\u306e\u81e8\u5e8a\u8a66\u9a13\u3084\u56fd\u5185\u306e\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u8abf\u67fb\u3067\u3001\u7279\u306b\u5973\u6027\u3067\u9aa8\u6298\u304c\u5897\u3048\u308b<\/strong>\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u9589\u7d4c\u5f8c\u306e\u65b9\u3001\u9aa8\u7c97\u9b06\u75c7\u306e\u3042\u308b\u65b9\u306f\u614e\u91cd\u306b\u691c\u8a0e\u3057\u307e\u3059<\/td>\n\u9aa8\u5bc6\u5ea6\u691c\u67fb\u3092\u53d7\u3051\u3066\u3044\u306a\u3044\u3001\u8ee2\u3073\u3084\u3059\u3044<\/td>\n<\/tr>\n
    \u8180\u80f1\u304c\u3093<\/strong><\/td>\n\u30ea\u30b9\u30af\u304c\u5897\u3048\u308b\u53ef\u80fd\u6027\u3092\u5b8c\u5168\u306b\u306f\u5426\u5b9a\u3067\u304d\u306a\u3044<\/strong>\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u8180\u80f1\u304c\u3093\u6cbb\u7642\u4e2d\u306e\u65b9\u306b\u306f\u4f7f\u308f\u305a\u3001\u65e2\u5f80\u304c\u3042\u308b\u65b9\u306f\u614e\u91cd\u306b\u5224\u65ad\u3002\u670d\u7528\u4e2d\u306f\u5b9a\u671f\u7684\u306b\u5c3f\u691c\u67fb\u3092\u884c\u3044\u307e\u3059<\/td>\n\u8840\u5c3f<\/strong>\u3001\u983b\u5c3f\u3001\u6392\u5c3f\u6642\u306e\u75db\u307f<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n\n
    \n

    \u7528\u8a9e\u89e3\u8aac\uff5c\u4f53\u6db2\u8caf\u7559\uff08\u305f\u3044\u3048\u304d\u3061\u3087\u308a\u3085\u3046\uff09\u3068\u306f<\/p>\n

    \u4f53\u306e\u4e2d\u306b\u6c34\u5206\u3068\u5869\u5206\u304c\u4f59\u5206\u306b\u305f\u307e\u3063\u305f\u72b6\u614b\u306e\u3053\u3068\u3067\u3059\u3002\u30d4\u30aa\u30b0\u30ea\u30bf\u30be\u30f3\u306f\u3001\u814e\u81d3\u306e\u300c\u96c6\u5408\u7ba1\uff08\u3057\u3085\u3046\u3054\u3046\u304b\u3093\uff09\u300d\u3068\u3044\u3046\u90e8\u5206\u3067\u30ca\u30c8\u30ea\u30a6\u30e0\u306e\u518d\u5438\u53ce\u3092\u4fc3\u3059\u3068\u8003\u3048\u3089\u308c\u3066\u304a\u308a\u3001\u305d\u306e\u7d50\u679c\u3001\u8840\u6db2\u306e\u91cf\uff08\u5faa\u74b0\u8840\u6f3f\u91cf\uff09\u304c\u5897\u3048\u307e\u3059\u3002<\/p>\n

    \u5897\u3048\u305f\u6c34\u5206\u306f\u8db3\u306e\u3080\u304f\u307f\u3068\u3057\u3066\u73fe\u308c\u308b\u307b\u304b\u3001\u5fc3\u81d3\u306b\u3068\u3063\u3066\u306f\u300c\u9001\u308a\u51fa\u3059\u8840\u6db2\u304c\u5897\u3048\u308b\uff1d\u8ca0\u62c5\u304c\u5897\u3048\u308b\u300d\u3053\u3068\u306b\u306a\u308a\u307e\u3059\u3002\u3082\u3068\u3082\u3068\u5fc3\u81d3\u306e\u529b\u304c\u5f31\u3063\u3066\u3044\u308b\u65b9\u3067\u306f\u3001\u3053\u308c\u304c\u5fc3\u4e0d\u5168\u306e\u5f15\u304d\u91d1<\/strong>\u306b\u306a\u308b\u305f\u3081\u3001\u4f7f\u7528\u524d\u306e\u554f\u8a3a\u3084\u5fc3\u96fb\u56f3\u30fb\u80f8\u90e8X\u7dda\u306a\u3069\u3067\u306e\u78ba\u8a8d\u304c\u5927\u5207\u3067\u3059\u3002\u3053\u306e\u307b\u304b\u983b\u5ea6\u306f\u4f4e\u3044\u3082\u306e\u306e\u3001\u809d\u6a5f\u80fd\u969c\u5bb3\u3084\u3001\u76ee\u306e\u7db2\u819c\u306e\u4e2d\u5fc3\u304c\u3080\u304f\u3080\u7cd6\u5c3f\u75c5\u9ec4\u6591\u6d6e\u816b<\/strong>\u306e\u5831\u544a\u3082\u3042\u308a\u3001\u5b9a\u671f\u7684\u306a\u63a1\u8840\u3084\u773c\u5e95\u691c\u67fb\u3092\u304a\u9858\u3044\u3057\u3066\u304a\u308a\u307e\u3059\u3002<\/p>\n<\/td>\n<\/tr>\n<\/table>\n

    \u306a\u304a\u3001\u30d4\u30aa\u30b0\u30ea\u30bf\u30be\u30f3\u5358\u72ec\u3067\u306f\u4f4e\u8840\u7cd6\u306f\u307e\u308c\u3067\u3059\u304c\u3001SU\u85ac\u3084\u30a4\u30f3\u30b9\u30ea\u30f3\u3068\u4f75\u7528\u3057\u3066\u3044\u308b\u5834\u5408\u306f\u4f4e\u8840\u7cd6\u304c\u8d77\u3053\u308a\u5f97\u307e\u3059<\/strong>\u3002\u4f4e\u8840\u7cd6\u306e\u5bfe\u51e6\u6cd5\u306f\u300c\u4f4e\u8840\u7cd6\u5bfe\u51e6\u5b8c\u5168\u30ac\u30a4\u30c9<\/a>\u300d\u3092\u3054\u53c2\u7167\u304f\u3060\u3055\u3044\u3002<\/p>\n

    \u30a4\u30e1\u30b0\u30ea\u30df\u30f3\uff08\u30c4\u30a4\u30df\u30fc\u30b0\uff09\u306e\u4ed5\u7d44\u307f\u3068\u7279\u5fb4<\/h2>\n

    \u30a4\u30e1\u30b0\u30ea\u30df\u30f3\uff08\u5546\u54c1\u540d\uff1a\u30c4\u30a4\u30df\u30fc\u30b0\u9320500mg\uff09<\/strong>\u306f\u30012021\u5e746\u670823\u65e5\u306b\u65e5\u672c\u3067\u627f\u8a8d\u3055\u308c\u3001\u540c\u5e749\u6708\u306b\u767a\u58f2\u3055\u308c\u305f\u6bd4\u8f03\u7684\u65b0\u3057\u3044\u304a\u85ac\u3067\u3059\u3002\u65e5\u672c\u304c\u4e16\u754c\u3067\u521d\u3081\u3066\u627f\u8a8d\u3057\u305f\u56fd<\/strong>\u3067\u3001\u300c\u30b0\u30ea\u30df\u30f3\u7cfb\u300d\u3068\u547c\u3070\u308c\u308b\u65b0\u3057\u3044\u7cfb\u7d71\u306b\u5206\u985e\u3055\u308c\u307e\u3059\u3002<\/p>\n

    \u30a4\u30e1\u30b0\u30ea\u30df\u30f3\u306e\u7279\u5fb4\u306f\u3001\u81b5\u81d3\uff08\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\uff09\u3068\u3001\u809d\u81d3\u30fb\u7b4b\u8089\uff08\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\uff09\u306e\u4e21\u65b9<\/strong>\u306b\u50cd\u304d\u304b\u3051\u308b\u3053\u3068\u3067\u3059\u3002\u305d\u306e\u4e2d\u5fc3\u306b\u3042\u308b\u306e\u304c\u3001\u7d30\u80de\u306e\u30a8\u30cd\u30eb\u30ae\u30fc\u5de5\u5834\u3067\u3042\u308b\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2<\/strong>\u306e\u50cd\u304d\u3092\u6574\u3048\u308b\u4f5c\u7528\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

    \n

    \u30e1\u30ab\u30cb\u30ba\u30e0\u56f3\u89e3\uff5c\u30a4\u30e1\u30b0\u30ea\u30df\u30f3\u306e\u300c2\u3064\u306e\u4f5c\u7528\u300d<\/p>\n\n\n\n\n\n
    1<\/text><\/svg><\/td>\n\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u6a5f\u80fd\u3092\u6539\u5584<\/strong>\uff1a\u81b5\u81d3\u30fb\u809d\u81d3\u30fb\u7b4b\u8089\u306e\u7d30\u80de\u3067\u3001\u30a8\u30cd\u30eb\u30ae\u30fc\u3092\u4f5c\u308b\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u50cd\u304d\u3092\u6574\u3048\u307e\u3059\u3002<\/td>\n<\/tr>\n
    2<\/text><\/svg><\/td>\n\u81b5\u81d3\uff1a\u8840\u7cd6\u304c\u9ad8\u3044\u3068\u304d\u3060\u3051\u30a4\u30f3\u30b9\u30ea\u30f3\u3092\u5897\u3084\u3059<\/strong>\uff08\u30b0\u30eb\u30b3\u30fc\u30b9\u6fc3\u5ea6\u4f9d\u5b58\u6027\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u306e\u4fc3\u9032\uff09\u3002<\/td>\n<\/tr>\n
    3<\/text><\/svg><\/td>\n\u809d\u81d3\u30fb\u7b4b\u8089\uff1a\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u3092\u6539\u5584<\/strong>\uff1a\u809d\u81d3\u3067\u306e\u7cd6\u306e\u65b0\u751f\u3092\u6291\u3048\u3001\u7b4b\u8089\u3067\u306e\u7cd6\u306e\u53d6\u308a\u8fbc\u307f\u3092\u9ad8\u3081\u307e\u3059\u3002<\/td>\n<\/tr>\n
    4<\/text><\/svg><\/td>\n\u5206\u6ccc\u4e0d\u5168\u3068\u62b5\u6297\u6027\u306e\u4e21\u65b9\u306b\u50cd\u304f<\/strong>\uff1a\u65e5\u672c\u4eba\u306b\u591a\u3044\u300c\u5206\u6ccc\u304c\u5c11\u306a\u3081\uff0b\u62b5\u6297\u6027\u3042\u308a\u300d\u306e\u30bf\u30a4\u30d7\u306b\u7406\u306b\u304b\u306a\u3063\u305f\u4f5c\u7528\u3067\u3059\u3002<\/td>\n<\/tr>\n<\/table>\n<\/div>\n\n\n
    \n

    \u7528\u8a9e\u89e3\u8aac\uff5c\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u30fb\u30b0\u30eb\u30b3\u30fc\u30b9\u6fc3\u5ea6\u4f9d\u5b58\u6027\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u3068\u306f<\/p>\n

    \u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\uff1a<\/strong>\u307b\u307c\u3059\u3079\u3066\u306e\u7d30\u80de\u306e\u4e2d\u306b\u3042\u308b\u5c0f\u3055\u306a\u5668\u5b98\u3067\u3001\u30d6\u30c9\u30a6\u7cd6\u3084\u8102\u80aa\u3092\u71c3\u3084\u3057\u3066\u3001\u7d30\u80de\u304c\u4f7f\u3046\u30a8\u30cd\u30eb\u30ae\u30fc\uff08ATP\uff09\u3092\u4f5c\u308b\u300c\u767a\u96fb\u6240\u300d\u3067\u3059\u3002\u7cd6\u5c3f\u75c5\u306e\u72b6\u614b\u3067\u306f\u3001\u81b5\u81d3\u306e\u03b2\u7d30\u80de\uff08\u30a4\u30f3\u30b9\u30ea\u30f3\u3092\u4f5c\u308b\u7d30\u80de\uff09\u3084\u7b4b\u8089\u30fb\u809d\u81d3\u3067\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u50cd\u304d\u304c\u843d\u3061\u3066\u3044\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

    \u30b0\u30eb\u30b3\u30fc\u30b9\u6fc3\u5ea6\u4f9d\u5b58\u6027\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\uff1a<\/strong>\u8840\u6db2\u4e2d\u306e\u30d6\u30c9\u30a6\u7cd6\uff08\u30b0\u30eb\u30b3\u30fc\u30b9\uff09\u6fc3\u5ea6\u304c\u9ad8\u3044\u3068\u304d\u306b\u3060\u3051\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u304c\u9ad8\u307e\u308b\u3001\u3068\u3044\u3046\u6027\u8cea\u306e\u3053\u3068\u3067\u3059\u3002\u8840\u7cd6\u5024\u304c\u4f4e\u3044\u3068\u304d\u306b\u306f\u5206\u6ccc\u3092\u7121\u7406\u306b\u5897\u3084\u3055\u306a\u3044\u305f\u3081\u3001\u5358\u72ec\u3067\u306f\u4f4e\u8840\u7cd6\u3092\u8d77\u3053\u3057\u306b\u304f\u3044<\/strong>\u306e\u304c\u5229\u70b9\u3067\u3059\uff08DPP-4\u963b\u5bb3\u85ac\u3084GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u3082\u540c\u3058\u6027\u8cea\u3092\u6301\u3061\u307e\u3059\uff09\u3002<\/p>\n<\/td>\n<\/tr>\n<\/table>\n

    \u6dfb\u4ed8\u6587\u66f8\u4e0a\u306e\u4f7f\u3044\u65b9\uff082026\u5e741\u6708\u6539\u8a02\u7248\uff09<\/h3>\n\n\n\n\n\n\n\n\n\n\n
    \u9805\u76ee<\/th>\n\u5185\u5bb9\uff08\u30a4\u30e1\u30b0\u30ea\u30df\u30f3\uff09<\/th>\n<\/tr>\n<\/thead>\n
    \u7528\u91cf<\/strong><\/td>\n1\u56de1,000mg\uff08500mg\u9320\u00d72\u9320\uff09\u30921\u65e52\u56de \u671d\u30fb\u5915<\/strong><\/td>\n<\/tr>\n
    \u814e\u6a5f\u80fd\u304c\u4f4e\u4e0b\u3057\u3066\u3044\u308b\u65b9<\/strong><\/td>\neGFR 15\u4ee5\u4e0a45\u672a\u6e80\uff1a1\u56de500mg\u30921\u65e52\u56de\u306b\u6e1b\u91cf<\/strong>
    eGFR 10\u4ee5\u4e0a15\u672a\u6e80\uff1a1\u56de500mg\u30921\u65e51\u56de\uff08\u6709\u76ca\u6027\u304c\u4e0a\u56de\u308b\u5834\u5408\u306e\u307f\uff09
    eGFR 10\u672a\u6e80\uff08\u900f\u6790\u4e2d\u3092\u542b\u3080\uff09\uff1a\u6295\u4e0e\u306f\u63a8\u5968\u3055\u308c\u306a\u3044<\/strong><\/td>\n<\/tr>\n
    \u4e3b\u306a\u526f\u4f5c\u7528<\/strong><\/td>\n\u5410\u304d\u6c17\u30fb\u4e0b\u75e2\u30fb\u4fbf\u79d8\u306a\u3069\u6d88\u5316\u5668\u75c7\u72b6\uff081\u301c5%\u672a\u6e80\uff09\u3002\u307e\u308c\u306b\u91cd\u5ea6\u306e\u98df\u6b32\u4f4e\u4e0b\u30fb\u5614\u5410\u304b\u3089\u8131\u6c34\u306b\u81f3\u3063\u305f\u4f8b\u306e\u5831\u544a\u3042\u308a<\/td>\n<\/tr>\n
    \u30e1\u30c8\u30db\u30eb\u30df\u30f3\u3068\u306e\u4f75\u7528<\/strong><\/td>\n\u4f5c\u7528\u306e\u4e00\u90e8\u304c\u5171\u901a\u3057\u3066\u3044\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u3001\u4f75\u7528\u521d\u671f\u306b\u6d88\u5316\u5668\u75c7\u72b6\u304c\u51fa\u3084\u3059\u3044<\/strong>\uff08\u9577\u671f\u8a66\u9a13\u3067\u4f75\u7528\u7fa4\u306e37.5%\u306b\u526f\u4f5c\u7528\u3001\u4e3b\u306b\u4e0b\u75e2\u30fb\u5410\u304d\u6c17\uff09<\/td>\n<\/tr>\n
    \u4f4e\u8840\u7cd6<\/strong><\/td>\n\u5358\u72ec\u3067\u306f\u8d77\u3053\u3057\u306b\u304f\u3044\u304c\u3001SU\u85ac\u4f75\u7528\u306711.8%\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u4f75\u7528\u306721.3%<\/strong>\u306b\u4f4e\u8840\u7cd6\uff08\u9577\u671f\u8a66\u9a13\uff09\u3002\u4f75\u7528\u85ac\u306e\u6e1b\u91cf\u3092\u691c\u8a0e\u3057\u307e\u3059<\/td>\n<\/tr>\n
    \u52b9\u679c\u5224\u5b9a<\/strong><\/td>\n3\u304b\u6708<\/strong>\u4f7f\u7528\u3057\u3066\u52b9\u679c\u304c\u4e0d\u5341\u5206\u306a\u3089\u3001\u6cbb\u7642\u306e\u5909\u66f4\u3092\u691c\u8a0e<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n\n
    \n

    \u7528\u8a9e\u89e3\u8aac\uff5ceGFR\uff08\u30a4\u30fc\u30fb\u30b8\u30fc\u30fb\u30a8\u30d5\u30fb\u30a2\u30fc\u30eb\uff09\u3068\u306f<\/p>\n

    \u63a8\u7b97\u7cf8\u7403\u4f53\u308d\u904e\u91cf\u306e\u3053\u3068\u3067\u3001\u8840\u6db2\u691c\u67fb\u306e\u30af\u30ec\u30a2\u30c1\u30cb\u30f3\u5024\u3068\u5e74\u9f62\u30fb\u6027\u5225\u304b\u3089\u8a08\u7b97\u3059\u308b\u300c\u814e\u81d3\u304c\u3069\u308c\u304f\u3089\u3044\u50cd\u3044\u3066\u3044\u308b\u304b\u300d\u306e\u76ee\u5b89\u3067\u3059\u3002\u5358\u4f4d\u306fmL\/\u5206\/1.73m\u00b2\u3067\u300160\u672a\u6e80\u304c\u7d9a\u304f\u3068\u6162\u6027\u814e\u81d3\u75c5\uff08CKD\uff09<\/strong>\u3068\u5224\u65ad\u3055\u308c\u307e\u3059\u3002\u30a4\u30e1\u30b0\u30ea\u30df\u30f3\u306f\u4e3b\u306b\u814e\u81d3\u304b\u3089\u6392\u6cc4\u3055\u308c\u308b\u305f\u3081\u3001eGFR\u306b\u5fdc\u3058\u3066\u91cf\u3092\u8abf\u6574\u3057\u307e\u3059\u3002\u304a\u85ac\u3092\u5b89\u5168\u306b\u4f7f\u3046\u305f\u3081\u3001\u5b9a\u671f\u7684\u306a\u63a1\u8840\u3092\u304a\u9858\u3044\u3057\u3066\u304a\u308a\u307e\u3059\u3002<\/p>\n<\/td>\n<\/tr>\n<\/table>\n

    2\u3064\u306e\u304a\u85ac\u306e\u6bd4\u8f03\u3068\u3001\u5916\u6765\u3067\u3088\u304f\u51fa\u4f1a\u3046\u30b1\u30fc\u30b9<\/h2>\n\n\n\n\n\n\n\n\n\n\n
    \u6bd4\u8f03\u9805\u76ee<\/th>\n\u30d4\u30aa\u30b0\u30ea\u30bf\u30be\u30f3<\/th>\n\u30a4\u30e1\u30b0\u30ea\u30df\u30f3<\/th>\n<\/tr>\n<\/thead>\n
    \u4e3b\u306a\u4f5c\u7528<\/strong><\/td>\n\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u306e\u6539\u5584\uff08\u8102\u80aa\u7d30\u80de\u306ePPAR\u03b3\uff09<\/td>\n\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u4fc3\u9032\uff0b\u62b5\u6297\u6027\u6539\u5584\uff08\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\uff09<\/td>\n<\/tr>\n
    \u98f2\u3080\u56de\u6570<\/strong><\/td>\n1\u65e51\u56de<\/td>\n1\u65e52\u56de\uff08\u671d\u30fb\u5915\uff09<\/td>\n<\/tr>\n
    \u5358\u72ec\u3067\u306e\u4f4e\u8840\u7cd6<\/strong><\/td>\n\u8d77\u3053\u3057\u306b\u304f\u3044<\/td>\n\u8d77\u3053\u3057\u306b\u304f\u3044<\/td>\n<\/tr>\n
    \u4f53\u91cd<\/strong><\/td>\n\u5897\u3048\u3084\u3059\u3044<\/strong>\uff08\u4f53\u6db2\u8caf\u7559\u30fb\u8102\u80aa\u306e\u518d\u5206\u5e03\uff09<\/td>\n\u5927\u304d\u304f\u306f\u5909\u308f\u308a\u306b\u304f\u3044<\/td>\n<\/tr>\n
    \u7279\u306b\u6ce8\u610f<\/strong><\/td>\n\u5fc3\u4e0d\u5168\uff08\u7981\u5fcc\uff09<\/strong>\u30fb\u3080\u304f\u307f\u30fb\u5973\u6027\u306e\u9aa8\u6298\u30fb\u8180\u80f1\u304c\u3093<\/td>\n\u6d88\u5316\u5668\u75c7\u72b6\uff08\u7279\u306b\u30e1\u30c8\u30db\u30eb\u30df\u30f3\u4f75\u7528\u521d\u671f\uff09\u30fb\u814e\u6a5f\u80fd\u306b\u5fdc\u3058\u305f\u6e1b\u91cf<\/td>\n<\/tr>\n
    \u5411\u3044\u3066\u3044\u308b\u65b9\u306e\u4f8b<\/strong><\/td>\n\u5185\u81d3\u8102\u80aa\u578b\u80a5\u6e80\u30fb\u8102\u80aa\u809d\u304c\u3042\u308a\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u304c\u5f37\u3044\u65b9\uff08\u5fc3\u4e0d\u5168\u3084\u9aa8\u7c97\u9b06\u75c7\u304c\u306a\u3044\u65b9\uff09<\/td>\n\u80a5\u6e80\u306e\u6709\u7121\u3092\u554f\u308f\u305a\u3001\u4f4e\u8840\u7cd6\u3092\u907f\u3051\u305f\u3044\u65b9\u3084\u3001\u4ed6\u5264\u3067\u526f\u4f5c\u7528\u304c\u51fa\u305f\u65b9\u306e\u8ffd\u52a0\u85ac\u3068\u3057\u3066<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

    \u3053\u3053\u304b\u3089\u306f\u3001\u7af9\u5185\u5185\u79d1\u5c0f\u5150\u79d1\u533b\u9662\u306e\u5916\u6765\u3067\u3088\u304f\u51fa\u4f1a\u3046\u3088\u3046\u306a\u60a3\u8005\u3055\u3093\u3092\u30a4\u30e1\u30fc\u30b8\u3057\u305f\u67b6\u7a7a\u306e\u30b1\u30fc\u30b9<\/strong>\u3067\u3054\u8aac\u660e\u3044\u305f\u3057\u307e\u3059\uff08\u5b9f\u5728\u306e\u60a3\u8005\u3055\u3093\u306e\u60c5\u5831\u3067\u306f\u3042\u308a\u307e\u305b\u3093\uff09\u3002<\/p>\n\n\n
    \n

    \u30b1\u30fc\u30b9\u2460\uff5c58\u6b73\u7537\u6027\u30fb\u4f1a\u793e\u54e1\uff08\u67b6\u7a7a\u306e\u75c7\u4f8b\uff09<\/p>\n

    BMI 28\u3001\u8179\u56f2 98cm\u3002\u5065\u8a3a\u3067\u8102\u80aa\u809d<\/strong>\u3068ALT\uff08\u809d\u6a5f\u80fd\u306e\u6570\u5024\uff09\u306e\u4e0a\u6607\u3092\u6307\u6458\u3002\u30e1\u30c8\u30db\u30eb\u30df\u30f3\u3092\u670d\u7528\u4e2d\u3067HbA1c 7.6%<\/strong>\u3002\u7a7a\u8179\u6642\u8840\u7cd6 140mg\/dL\u30fb\u7a7a\u8179\u6642\u30a4\u30f3\u30b9\u30ea\u30f3 12\u03bcU\/mL\u304b\u3089\u8a08\u7b97\u3057\u305fHOMA-IR\u306f\u7d044.1<\/strong>\u3068\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u304c\u306f\u3063\u304d\u308a\u3057\u3066\u3044\u307e\u3059\u3002\u5fc3\u81d3\u306e\u75c5\u6c17\u306f\u306a\u304f\u3001\u5fc3\u96fb\u56f3\u3082\u6b63\u5e38\u3002<\/p>\n

    \u8003\u3048\u65b9\uff1a<\/strong>\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u304c\u4e3b\u4f53\u3067\u3001\u8102\u80aa\u809d\u3082\u3042\u308b\u30bf\u30a4\u30d7\u3067\u3059\u3002\u4f53\u91cd\u3092\u6e1b\u3089\u3057\u305f\u3044\u65b9\u3067\u306fSGLT2\u963b\u5bb3\u85ac\u3084GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u3082\u6709\u529b\u306a\u5019\u88dc\u3068\u306a\u308a\u307e\u3059\u304c\u3001\u3080\u304f\u307f\u3084\u4f53\u91cd\u306e\u5909\u5316\u3092\u4e00\u7dd2\u306b\u78ba\u8a8d\u3067\u304d\u308b\u5834\u5408\u306b\u306f\u30d4\u30aa\u30b0\u30ea\u30bf\u30be\u30f3\uff08\u5c11\u91cf\u304b\u3089\uff09<\/strong>\u3082\u9078\u629e\u80a2\u306b\u306a\u308a\u307e\u3059\u3002\u3069\u306e\u85ac\u3092\u9078\u3093\u3067\u3082\u3001\u5185\u81d3\u8102\u80aa\u3092\u6e1b\u3089\u3059\u98df\u4e8b\u7642\u6cd5\u30fb\u904b\u52d5\u7642\u6cd5\u304c\u571f\u53f0\u3067\u3042\u308b\u3053\u3068\u306b\u5909\u308f\u308a\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n<\/td>\n<\/tr>\n<\/table>\n\n\n
    \n

    \u30b1\u30fc\u30b9\u2461\uff5c73\u6b73\u5973\u6027\u30fb\u4e00\u4eba\u66ae\u3089\u3057\uff08\u67b6\u7a7a\u306e\u75c7\u4f8b\uff09<\/p>\n

    BMI 22\u3001DPP-4\u963b\u5bb3\u85ac\u3092\u670d\u7528\u4e2d\u3067HbA1c 7.8%<\/strong>\u3002\u9aa8\u7c97\u9b06\u75c7\u306e\u6cbb\u7642\u4e2d\u3067\u3001eGFR\u306f42\u3002\u4ee5\u524d\u3001SU\u85ac\u3067\u4f4e\u8840\u7cd6\u3092\u8d77\u3053\u3057\u305f\u7d4c\u9a13\u304c\u3042\u308a\u3001\u304a\u4e00\u4eba\u306e\u6642\u9593\u304c\u9577\u3044\u305f\u3081\u4f4e\u8840\u7cd6\u304c\u5fc3\u914d\u3067\u3059\u3002<\/p>\n

    \u8003\u3048\u65b9\uff1a<\/strong>\u5973\u6027\u3067\u9aa8\u7c97\u9b06\u75c7\u304c\u3042\u308b\u305f\u3081\u3001\u9aa8\u6298\u30ea\u30b9\u30af\u306e\u70b9\u3067\u30d4\u30aa\u30b0\u30ea\u30bf\u30be\u30f3\u306f\u614e\u91cd\u306b<\/strong>\u8003\u3048\u307e\u3059\u3002\u4f4e\u8840\u7cd6\u3092\u907f\u3051\u305f\u3044\u3053\u3068\u3082\u8e0f\u307e\u3048\u3001\u30a4\u30e1\u30b0\u30ea\u30df\u30f3\u3092\u814e\u6a5f\u80fd\u306b\u5408\u308f\u305b\u3066\u6e1b\u91cf\uff081\u56de500mg\u30fb1\u65e52\u56de\uff09<\/strong>\u3057\u3066\u8ffd\u52a0\u3059\u308b\u3001\u3068\u3044\u3046\u9078\u629e\u80a2\u304c\u691c\u8a0e\u3067\u304d\u307e\u3059\u3002\u9ad8\u9f62\u306e\u65b9\u3067\u306f\u8840\u7cd6\u3092\u300c\u4e0b\u3052\u3059\u304e\u306a\u3044\u300d\u3053\u3068\u3082\u5927\u5207\u3067\u3001\u76ee\u6a19HbA1c\u306f\u5e74\u9f62\u30fb\u8a8d\u77e5\u6a5f\u80fd\u30fb\u304a\u85ac\u306e\u7a2e\u985e\u3067\u500b\u5225\u306b\u6c7a\u3081\u307e\u3059\uff08\u8a73\u3057\u304f\u306f\u300c\u9ad8\u9f62\u8005\u306e\u7cd6\u5c3f\u75c5\u306f\u300c\u4e0b\u3052\u3059\u304e\u300d\u306b\u3082\u3054\u6ce8\u610f\u3092<\/a>\u300d\uff09\u3002<\/p>\n<\/td>\n<\/tr>\n<\/table>\n

    \u3053\u306e\u3088\u3046\u306b\u3001\u540c\u3058\u300c\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u306b\u50cd\u304f\u304a\u85ac\u300d\u3067\u3082\u3001\u4f53\u578b\u30fb\u809d\u81d3\u30fb\u5fc3\u81d3\u30fb\u9aa8\u30fb\u814e\u81d3\u306e\u72b6\u614b<\/strong>\u306b\u3088\u3063\u3066\u5411\u304d\u4e0d\u5411\u304d\u304c\u5927\u304d\u304f\u5909\u308f\u308a\u307e\u3059\u3002\u304a\u85ac\u306e\u9078\u629e\u306f\u691c\u67fb\u7d50\u679c\u3068\u751f\u6d3b\u80cc\u666f\u3092\u3075\u307e\u3048\u3066\u533b\u5e2b\u3068\u76f8\u8ac7\u3057\u306a\u304c\u3089\u6c7a\u3081\u308b\u3082\u306e\u3067\u3059\u306e\u3067\u3001\u3054\u81ea\u8eab\u306e\u5224\u65ad\u3067\u85ac\u3092\u5909\u66f4\u30fb\u4e2d\u6b62\u3059\u308b\u3053\u3068\u306f\u907f\u3051\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n

    \u670d\u7528\u4e2d\u306e\u65b9\u3078\u306e\u304a\u9858\u3044\u30fb\u53d7\u8a3a\u306e\u76ee\u5b89<\/h2>\n\n\n
    \n

    \u91cd\u8981\uff5c\u3059\u3050\u306b\u3054\u9023\u7d61\u30fb\u53d7\u8a3a\u3044\u305f\u3060\u304d\u305f\u3044\u30b5\u30a4\u30f3<\/p>\n

    \u30fb\u3010\u30d4\u30aa\u30b0\u30ea\u30bf\u30be\u30f3\u3011\u6025\u306a\u4f53\u91cd\u5897\u52a0\u3001\u8db3\u3084\u9854\u306e\u3080\u304f\u307f\u3001\u606f\u5207\u308c\u30fb\u6a2a\u306b\u306a\u308b\u3068\u82e6\u3057\u3044<\/p>\n

    \u30fb\u3010\u30d4\u30aa\u30b0\u30ea\u30bf\u30be\u30f3\u3011\u8840\u5c3f\u30fb\u983b\u5c3f\u30fb\u6392\u5c3f\u6642\u306e\u75db\u307f\u3001\u3060\u308b\u3055\u3084\u9ec4\u75b8\uff08\u767d\u76ee\u304c\u9ec4\u8272\u3044\uff09<\/p>\n

    \u30fb\u3010\u30a4\u30e1\u30b0\u30ea\u30df\u30f3\u3011\u98df\u4e8b\u304c\u3068\u308c\u306a\u3044\u307b\u3069\u306e\u5410\u304d\u6c17\u30fb\u5614\u5410\u3001\u4e0b\u75e2\u304c\u7d9a\u304d\u8131\u6c34\u304c\u5fc3\u914d<\/p>\n

    \u30fb\u3010\u5171\u901a\u30fb\u4f75\u7528\u85ac\u3042\u308a\u3011\u51b7\u3084\u6c57\u30fb\u52d5\u60b8\u30fb\u624b\u306e\u3075\u308b\u3048\u306a\u3069\u4f4e\u8840\u7cd6\u306e\u75c7\u72b6<\/p>\n<\/td>\n<\/tr>\n<\/table>\n\n\n
    \n

    \u30b7\u30c3\u30af\u30c7\u30a4\uff08\u4f53\u8abf\u4e0d\u826f\u306e\u65e5\uff09\u306b\u3064\u3044\u3066<\/p>\n

    \u767a\u71b1\u30fb\u5614\u5410\u30fb\u4e0b\u75e2\u306a\u3069\u3067\u98df\u4e8b\u304c\u3068\u308c\u306a\u3044\u65e5\u306f\u3001\u304a\u85ac\u306e\u98f2\u307f\u65b9\u3092\u4e00\u6642\u7684\u306b\u5909\u3048\u308b\u5fc5\u8981\u304c\u3042\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u3084\u80c3\u8178\u708e\u304c\u5897\u3048\u308b\u3053\u308c\u304b\u3089\u306e\u5b63\u7bc0\u306f\u7279\u306b\u3054\u6ce8\u610f\u304f\u3060\u3055\u3044\u3002\u3042\u3089\u304b\u3058\u3081\u4e3b\u6cbb\u533b\u3068\u300c\u30b7\u30c3\u30af\u30c7\u30a4\u30eb\u30fc\u30eb\u300d\u3092\u6c7a\u3081\u3066\u304a\u304f\u3068\u5b89\u5fc3\u3067\u3059\uff08\u8a73\u3057\u304f\u306f\u300c\u8840\u7cd6\u5024\u306e\u300c\u4e0a\u304c\u308a\u3059\u304e\u300d\u3082\u7dca\u6025\u4e8b\u614b\u3067\u3059\uff5c\u30b7\u30c3\u30af\u30c7\u30a4\u306e\u4f11\u85ac\u30eb\u30fc\u30eb<\/a>\u300d\uff09\u3002<\/p>\n<\/td>\n<\/tr>\n<\/table>\n\n\n
    \n

    \u53d7\u8a3a\u524d\u30c1\u30a7\u30c3\u30af\u30ea\u30b9\u30c8<\/p>\n

    \u25a1 \u6700\u8fd1\u306e\u5065\u8a3a\u7d50\u679c\uff08HbA1c\u30fb\u809d\u6a5f\u80fd\u30fb\u814e\u6a5f\u80fdeGFR\u30fb\u5c3f\u691c\u67fb\uff09<\/p>\n

    \u25a1 \u670d\u7528\u4e2d\u306e\u304a\u85ac\u30fb\u304a\u85ac\u624b\u5e33\uff08\u4ed6\u9662\u306e\u51e6\u65b9\u30fb\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u3082\u542b\u3081\u3066\uff09<\/p>\n

    \u25a1 \u5fc3\u81d3\u306e\u75c5\u6c17\u30fb\u5fc3\u4e0d\u5168\u3068\u8a00\u308f\u308c\u305f\u3053\u3068\u304c\u3042\u308b\u304b<\/p>\n

    \u25a1 \u9aa8\u7c97\u9b06\u75c7\u30fb\u9aa8\u6298\u306e\u7d4c\u9a13\uff08\u7279\u306b\u5973\u6027\u306e\u65b9\uff09<\/p>\n

    \u25a1 \u8180\u80f1\u306e\u75c5\u6c17\u30fb\u8840\u5c3f\u3092\u6307\u6458\u3055\u308c\u305f\u3053\u3068\u304c\u3042\u308b\u304b<\/p>\n

    \u25a1 \u3053\u3053\u6570\u304b\u6708\u306e\u4f53\u91cd\u306e\u5909\u5316\u30fb\u3080\u304f\u307f\u306e\u6709\u7121<\/p>\n<\/td>\n<\/tr>\n<\/table>\n

    \u7af9\u5185\u5185\u79d1\u5c0f\u5150\u79d1\u533b\u9662\u3067\u8a3a\u308b\u3068\u3044\u3046\u9078\u629e\uff08\u5f53\u9662\u304c\u9078\u3070\u308c\u308b\u7406\u7531\uff09<\/h2>\n

    \u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u306b\u50cd\u304f\u304a\u85ac\u306f\u3001\u52b9\u679c\u3060\u3051\u3067\u306a\u304f\u5fc3\u81d3\u30fb\u9aa8\u30fb\u814e\u81d3\u30fb\u809d\u81d3\u307e\u3067\u898b\u6e21\u3057\u3066\u9078\u3076\u3053\u3068\u304c\u5927\u5207\u3067\u3059\u3002\u5f53\u9662\u3067\u306f\u3001\u6b21\u306e\u3088\u3046\u306a\u4f53\u5236\u3067\u7cd6\u5c3f\u75c5\u306e\u8a3a\u7642\u3092\u884c\u3063\u3066\u304a\u308a\u307e\u3059\u3002<\/p>\n

    \n
    \n

    \u7406\u7531\u2460\u3000\u7cd6\u5c3f\u75c5\u30fb\u751f\u6d3b\u7fd2\u6163\u75c5\u306e\u5c02\u9580\u7684\u8a3a\u7642<\/p>\n

    \u65e5\u672c\u7cd6\u5c3f\u75c5\u5354\u4f1a\u767b\u9332\u533b\u30fb\u65e5\u672c\u6297\u52a0\u9f62\u533b\u5b66\u4f1a\u5c02\u9580\u533b\u306e\u9662\u9577\u304c\u5916\u6765\u3067\u76f4\u63a5\u8a3a\u5bdf\u3057\u3001HOMA-IR\u3084\u814e\u6a5f\u80fd\u30fb\u809d\u6a5f\u80fd\u306a\u3069\u306e\u691c\u67fb\u3092\u3075\u307e\u3048\u3066\u304a\u85ac\u3092\u9078\u3073\u307e\u3059\u3002<\/p>\n<\/p><\/div>\n

    \n

    \u7406\u7531\u2461\u3000\u773c\u5e95\u30fb\u5408\u4f75\u75c7\u307e\u3067\u307e\u3068\u3081\u3066\u78ba\u8a8d<\/p>\n

    \u30c7\u30b8\u30bf\u30eb\u7121\u6563\u77b3\u773c\u5e95\u30ab\u30e1\u30e9\u3092\u5099\u3048\u3001\u6563\u77b3\u305b\u305a\u306b\u773c\u5e95\u306e\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u304c\u3067\u304d\u307e\u3059\u3002\u7570\u5e38\u304c\u3042\u308c\u3070\u8fd1\u96a3\u306e\u773c\u79d1\u5c02\u9580\u533b\u3078\u3054\u7d39\u4ecb\u3057\u307e\u3059\u3002<\/p>\n<\/p><\/div>\n

    \n

    \u7406\u7531\u2462\u3000\u5185\u79d1\u00d7\u5c0f\u5150\u79d1\u3067\u3054\u5bb6\u65cf\u305d\u308d\u3063\u3066<\/p>\n

    \u5185\u79d1\u3068\u5c0f\u5150\u79d1\u3092\u4f75\u8a2d\u3057\u3066\u304a\u308a\u3001\u304a\u5b50\u3055\u307e\u304b\u3089\u3054\u9ad8\u9f62\u306e\u65b9\u307e\u3067\u540c\u3058\u7a93\u53e3\u3067\u3054\u76f8\u8ac7\u3044\u305f\u3060\u3051\u307e\u3059\u3002<\/p>\n<\/p><\/div>\n

    \n

    \u7406\u7531\u2463\u3000\u591a\u6469\u5ddd\u99c5\u5f92\u6b695\u5206\u30fb\u571f\u66dc\u5348\u524d\u3082\u8a3a\u7642<\/p>\n

    \u53d7\u4ed8\u306f\u5348\u524d12\u6642\u307e\u3067\u30fb\u5348\u5f8c19\u6642\u307e\u3067\u3002\u5e73\u65e5\u304a\u5fd9\u3057\u3044\u65b9\u3082\u3001\u571f\u66dc\u5348\u524d\u306b\u5b9a\u671f\u901a\u9662\u3044\u305f\u3060\u3051\u307e\u3059\u3002<\/p>\n<\/p><\/div>\n

    \n

    \u7406\u7531\u2464\u3000\u4e94\u826f\u4f1a\u30b0\u30eb\u30fc\u30d7\u3067\u5207\u308c\u76ee\u306a\u304f\u9023\u643a<\/p>\n

    \u5185\u8996\u93e1\u691c\u67fb\u3084\u5c02\u9580\u5916\u6765\u304c\u5fc5\u8981\u306a\u5834\u5408\u306f\u3001\u4e94\u826f\u4f1a\u30af\u30ea\u30cb\u30c3\u30af\u767d\u91d1\u9ad8\u8f2a\u3078\u30b9\u30e0\u30fc\u30ba\u306b\u3054\u7d39\u4ecb\u3057\u307e\u3059\u3002<\/p>\n<\/p><\/div>\n

    \n

    \u7406\u7531\u2465\u3000\u8a2a\u554f\u8a3a\u7642\u30fb\u5730\u57df\u5bc6\u7740<\/p>\n

    \u901a\u9662\u304c\u96e3\u3057\u304f\u306a\u3063\u305f\u65b9\u306b\u306f\u8a2a\u554f\u8a3a\u7642\u306b\u3082\u5bfe\u5fdc\u3057\u3001\u7530\u5712\u8abf\u5e03\u30fb\u5927\u7530\u533a\u306e\u5730\u57df\u3067\u9577\u304f\u8840\u7cd6\u7ba1\u7406\u3092\u7d9a\u3051\u3089\u308c\u308b\u4f53\u5236\u3092\u6574\u3048\u3066\u3044\u307e\u3059\u3002<\/p>\n<\/p><\/div>\n<\/div>\n

    \n

    \u4eca\u306e\u304a\u85ac\u304c\u81ea\u5206\u306e\u4f53\u8cea\u306b\u5408\u3063\u3066\u3044\u308b\u304b\u6c17\u306b\u306a\u308b\u65b9\u306f\u3001\u304a\u6c17\u8efd\u306b\u3054\u76f8\u8ac7\u304f\u3060\u3055\u3044\u3002<\/p>\n

    WEB\u4e88\u7d04\u306f\u3053\u3061\u3089<\/a>\u96fb\u8a71\u3067\u4e88\u7d04 03-3721-5222<\/a><\/div>\n<\/div>\n
    \n \"\u533b\u7642\u6cd5\u4eba\u793e\u56e3<\/p>\n

    AUTHOR \/ SUPERVISOR\uff5c\u3053\u306e\u8a18\u4e8b\u306e\u57f7\u7b46\u533b\u5e2b<\/p>\n

    \u7af9\u5185\u5185\u79d1\u5c0f\u5150\u79d1\u533b\u9662 \u9662\u9577\u3000\u4e94\u85e4 \u826f\u5c06\uff08\u3054\u3068\u3046 \u3088\u3057\u307e\u3055\uff09<\/span><\/p>\n