{"id":6978,"date":"2026-05-10T16:39:05","date_gmt":"2026-05-10T07:39:05","guid":{"rendered":"https:\/\/www.takeuchi-iin.jp\/blog\/?p=6978"},"modified":"2026-05-10T18:10:35","modified_gmt":"2026-05-10T09:10:35","slug":"blog-gut-fermented-immunity-2026","status":"publish","type":"post","link":"https:\/\/www.takeuchi-iin.jp\/blog\/blog-gut-fermented-immunity-2026\/","title":{"rendered":"\u8178\u5185\u30d5\u30ed\u30fc\u30e9\u3068\u514d\u75ab\u2015\u2015\u767a\u9175\u98df\u54c1\u306e\u9078\u3073\u65b9"},"content":{"rendered":"

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\n

\u76ee\u6b21<\/p>\n

    \n
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  2. \u8178\u5185\u30d5\u30ed\u30fc\u30e9\u3068\u514d\u75ab\u30d0\u30e9\u30f3\u30b9\u306e\u30e1\u30ab\u30cb\u30ba\u30e0<\/a><\/li>\n
  3. \u30d7\u30ed\u30d0\u30a4\u30aa\u30c6\u30a3\u30af\u30b9\uff0f\u30d7\u30ec\u30d0\u30a4\u30aa\u30c6\u30a3\u30af\u30b9\uff0f\u30dd\u30b9\u30c8\u30d0\u30a4\u30aa\u30c6\u30a3\u30af\u30b9<\/a><\/li>\n
  4. \u767a\u9175\u98df\u54c1\u306e\u6bd4\u8f03\u8868\u2015\u2015\u30e8\u30fc\u30b0\u30eb\u30c8\u30fb\u7d0d\u8c46\u30fb\u5473\u564c\u30fb\u30ad\u30e0\u30c1\u30fb\u306c\u304b\u6f2c\u3051<\/a><\/li>\n
  5. \u6bce\u65e5\u7d9a\u3051\u308b\u305f\u3081\u306e\u7d44\u307f\u5408\u308f\u305b\u4f8b\uff08\u671d\u30fb\u663c\u30fb\u591c\uff09<\/a><\/li>\n
  6. \u6ce8\u610f\u70b9\uff5c\u5869\u5206\u30fb\u30a2\u30ec\u30eb\u30ae\u30fc\u30fb\u4e73\u7cd6\u4e0d\u8010<\/a><\/li>\n
  7. \u53c2\u8003\u6587\u732e<\/a><\/li>\n<\/ol>\n<\/div>\n

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    \n

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    \n

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    \n3<\/text><\/svg>\n<\/td>\n\u5236\u5fa1\u6027T\u7d30\u80de\uff08Treg\uff09\u304c\u8a98\u5c0e\u3055\u308c\u308b<\/strong>\uff1a\u916a\u9178\u304c\u5927\u8178\u306e\u7c98\u819c\u514d\u75ab\u306b\u4f5c\u7528\u3057\u3001\u904e\u5270\u306a\u708e\u75c7\u3092\u6291\u3048\u308b\u300c\u5236\u5fa1\u6027T\u7d30\u80de\u300d\u3092\u5897\u3084\u3057\u307e\u3059\u3002\u30a2\u30ec\u30eb\u30ae\u30fc\u30fb\u81ea\u5df1\u514d\u75ab\u75be\u60a3\u306e\u6291\u5236\u306b\u5bc4\u4e0e\u3057\u307e\u3059\u3002<\/td>\n<\/tr>\n
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    \u30dd\u30b9\u30c8\u30d0\u30a4\u30aa\u30c6\u30a3\u30af\u30b9<\/strong><\/td>\n\u6709\u7528\u83cc\u304c\u7523\u751f\u3059\u308b\u4ee3\u8b1d\u7269\u30fb\u83cc\u4f53\u6210\u5206<\/td>\n\u77ed\u9396\u8102\u80aa\u9178\uff08\u916a\u9178\u30fb\u9162\u9178\uff09\u3001\u6b7b\u83cc\u4f53<\/td>\n<\/tr>\n
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    \u98df\u54c1<\/th>\n\u4e3b\u306a\u83cc<\/th>\n\u7279\u5fb4\u30fb\u671f\u5f85\u3055\u308c\u308b\u52b9\u679c<\/th>\n1\u65e5\u306e\u76ee\u5b89<\/th>\n<\/tr>\n<\/thead>\n
    \u30e8\u30fc\u30b0\u30eb\u30c8<\/strong><\/td>\n\u4e73\u9178\u83cc\u3001\u30d3\u30d5\u30a3\u30ba\u30b9\u83cc<\/td>\n\u4fbf\u901a\u6539\u5584\u3001\u611f\u67d3\u9632\u5fa1\u3001\u83cc\u682a\u306b\u3088\u308a\u82b1\u7c89\u75c7\u7de9\u548c\u306e\u5831\u544a\u3042\u308a<\/td>\n100\u301c200g<\/td>\n<\/tr>\n
    \u7d0d\u8c46<\/strong><\/td>\n\u7d0d\u8c46\u83cc\uff08\u67af\u8349\u83cc\uff09<\/td>\n\u30d3\u30bf\u30df\u30f3K2\u8c4a\u5bcc\u3001\u30ca\u30c3\u30c8\u30a6\u30ad\u30ca\u30fc\u30bc\u3001\u5927\u8c46\u30a4\u30bd\u30d5\u30e9\u30dc\u30f3<\/td>\n1\u30d1\u30c3\u30af\uff0840\u301c50g\uff09<\/td>\n<\/tr>\n
    \u5473\u564c<\/strong><\/td>\n\u9eb9\u83cc\u3001\u9175\u6bcd\u3001\u4e73\u9178\u83cc<\/td>\n\u30a2\u30df\u30ce\u9178\u3001\u30da\u30d7\u30c1\u30c9\u3001\u6297\u9178\u5316\u4f5c\u7528\u3001\u548c\u98df\u306e\u57fa\u672c<\/td>\n\u5473\u564c\u6c411\u676f\uff08\u5473\u564c\u7d0412g\uff09<\/td>\n<\/tr>\n
    \u30ad\u30e0\u30c1<\/strong><\/td>\n\u4e73\u9178\u83cc\uff08\u30e9\u30d6\u30ec\u83cc\u985e\uff09<\/td>\n\u690d\u7269\u6027\u4e73\u9178\u83cc\u306f\u80c3\u9178\u306b\u5f37\u3044\u3001\u30ab\u30d7\u30b5\u30a4\u30b7\u30f3\u3067\u4ee3\u8b1dUP<\/td>\n30\u301c50g<\/td>\n<\/tr>\n
    \u306c\u304b\u6f2c\u3051<\/strong><\/td>\n\u4e73\u9178\u83cc\u3001\u9175\u6bcd<\/td>\n\u30d3\u30bf\u30df\u30f3B1\u5f37\u5316\u3001\u690d\u7269\u6027\u4e73\u9178\u83cc\u3001\u65e5\u672c\u306e\u4f1d\u7d71\u767a\u9175\u98df\u54c1<\/td>\n\u5c0f\u76bf1\u301c2\u5207\u308c<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

    \u6bce\u65e5\u7d9a\u3051\u308b\u305f\u3081\u306e\u7d44\u307f\u5408\u308f\u305b\u4f8b\uff08\u671d\u30fb\u663c\u30fb\u591c\uff09<\/h2>\n

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    \u98df\u4e8b<\/th>\n\u767a\u9175\u98df\u54c1\u306e\u53d6\u308a\u5165\u308c\u65b9<\/th>\n\u30d7\u30ec\u30d0\u30a4\u30aa\u30c6\u30a3\u30af\u30b9\uff08\u98df\u7269\u7e4a\u7dad\u30fb\u30aa\u30ea\u30b4\u7cd6\uff09<\/th>\n<\/tr>\n<\/thead>\n
    \u671d<\/strong><\/td>\n\u30d7\u30ec\u30fc\u30f3\u30e8\u30fc\u30b0\u30eb\u30c8<\/td>\n\u30d0\u30ca\u30ca\u3001\u30ad\u30a6\u30a4\u3001\u30d9\u30ea\u30fc\u985e\u3001\u30aa\u30fc\u30c8\u30df\u30fc\u30eb<\/td>\n<\/tr>\n
    \u663c<\/strong><\/td>\n\u5473\u564c\u6c41\u3001\u306c\u304b\u6f2c\u3051\uff08\u5b9a\u98df\u30b9\u30bf\u30a4\u30eb\uff09<\/td>\n\u6d77\u85fb\u3001\u6839\u83dc\u3001\u304d\u306e\u3053\u985e<\/td>\n<\/tr>\n
    \u591c<\/strong><\/td>\n\u7d0d\u8c46\u3001\u30ad\u30e0\u30c1\u3001\u5473\u564c\u6c41<\/td>\n\u7389\u306d\u304e\u3001\u3054\u307c\u3046\u3001\u5927\u8c46\u88fd\u54c1\u3001\u3082\u3061\u9ea6<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n\n
    \n

    \u7d9a\u3051\u308b\u30b3\u30c4<\/p>\n

    \u25a1 \u300c1\u65e53\u54c1\u300d\u3067\u306f\u306a\u304f\u300c1\u65e51\u54c1\u3067\u3082OK\u300d\u3068\u30cf\u30fc\u30c9\u30eb\u3092\u4e0b\u3052\u308b<\/p>\n

    \u25a1 \u540c\u3058\u83cc\u3067\u306f\u98fd\u304d\u308b\u306e\u3067\u30011\u301c2\u9031\u9593\u3054\u3068\u306b\u30e8\u30fc\u30b0\u30eb\u30c8\u306e\u7a2e\u985e\u3092\u5909\u3048\u3066\u307f\u308b<\/p>\n

    \u25a1 \u767a\u9175\u98df\u54c1\uff0b\u98df\u7269\u7e4a\u7dad\uff08\u30b7\u30f3\u30d0\u30a4\u30aa\u30c6\u30a3\u30af\u30b9\uff09\u3067\u52b9\u679c\u3092\u5e95\u4e0a\u3052\u3059\u308b<\/p>\n<\/td>\n<\/tr>\n<\/table>\n

    \u6ce8\u610f\u70b9\uff5c\u5869\u5206\u30fb\u30a2\u30ec\u30eb\u30ae\u30fc\u30fb\u4e73\u7cd6\u4e0d\u8010<\/h2>\n

    \u767a\u9175\u98df\u54c1\u306f\u57fa\u672c\u7684\u306b\u5b89\u5168\u306a\u98df\u6750\u3067\u3059\u304c\u3001\u3044\u304f\u3064\u304b\u533b\u5b66\u7684\u306a\u6ce8\u610f\u70b9\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n
    \n

    \u3053\u3093\u306a\u65b9\u306f\u6442\u308a\u65b9\u306b\u5de5\u592b\u3092<\/p>\n

    \u30fb\u9ad8\u8840\u5727\u306e\u65b9<\/strong>\uff1a\u5473\u564c\u30fb\u30ad\u30e0\u30c1\u30fb\u306c\u304b\u6f2c\u3051\u306f\u5869\u5206\u304c\u591a\u3044\u3067\u3059\u3002\u6e1b\u5869\u5473\u564c\u30fb\u7121\u5869\u30ad\u30e0\u30c1\u3092\u9078\u3073\u3001\u91cf\u3092\u63a7\u3048\u3081\u306b\uff08\u5473\u564c\u6c41\u306f1\u65e51\u676f\u307e\u3067\uff09\u3002<\/p>\n

    \u30fb\u725b\u4e73\u30a2\u30ec\u30eb\u30ae\u30fc\u30fb\u4e73\u7cd6\u4e0d\u8010\u306e\u65b9<\/strong>\uff1a\u30e8\u30fc\u30b0\u30eb\u30c8\u3067\u304a\u8179\u304c\u5f35\u308b\u30fb\u4e0b\u75e2\u3059\u308b\u5834\u5408\u306f\u3001\u8c46\u4e73\u30e8\u30fc\u30b0\u30eb\u30c8\u30fb\u7518\u9152\u30fb\u7d0d\u8c46\u30fb\u5473\u564c\u306b\u7f6e\u304d\u63db\u3048\u3092\u3002<\/p>\n

    \u30fb\u30ef\u30eb\u30d5\u30a1\u30ea\u30f3\u670d\u7528\u4e2d\u306e\u65b9<\/strong>\uff1a\u7d0d\u8c46\u306f\u30d3\u30bf\u30df\u30f3K2\u304c\u8c4a\u5bcc\u3067\u85ac\u52b9\u3092\u6253\u3061\u6d88\u3059\u305f\u3081\u3001\u539f\u5247\u7981\u5fcc\u3002\u7d0d\u8c46\u83cc\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u3082\u907f\u3051\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n

    \u30fb\u304a\u5b50\u3055\u307e<\/strong>\uff1a1\u6b73\u672a\u6e80\u306e\u306f\u3061\u307f\u3064\u5165\u308a\u767a\u9175\u98df\u54c1\u306f\u53b3\u7981\u3002\u30e8\u30fc\u30b0\u30eb\u30c8\u306f\u751f\u5f8c7\u301c8\u304b\u6708\u4ee5\u964d\u304b\u3089\u5c11\u91cf\u305a\u3064\u3002<\/p>\n<\/td>\n<\/tr>\n<\/table>\n

    \u5f53\u9662\u3067\u306f\u3001\u4fbf\u901a\u7570\u5e38\u30fb\u904e\u654f\u6027\u8178\u75c7\u5019\u7fa4\uff08IBS\uff09\u30fb\u30a2\u30ec\u30eb\u30ae\u30fc\u30fb\u5c0f\u5150\u306e\u98df\u7269\u6307\u5c0e\u307e\u3067\u3001\u8178\u3092\u5207\u308a\u53e3\u3068\u3057\u305f\u8a3a\u7642<\/strong>\u3092\u5185\u79d1\u30fb\u5c0f\u5150\u79d1\u4f75\u8a2d\u306e\u5f37\u307f\u3092\u6d3b\u304b\u3057\u3066\u884c\u3063\u3066\u304a\u308a\u307e\u3059\u3002\u300c\u3046\u3061\u306e\u5b50\u306e\u30e8\u30fc\u30b0\u30eb\u30c8\u306f\u3053\u308c\u3067\u3044\u3044\u304b\u300d\u300c\u81ea\u5206\u306e\u304a\u8179\u306e\u5f35\u308a\u306f\u4f55\u304c\u539f\u56e0\u304b\u300d\u306a\u3069\u3001\u3054\u5bb6\u65cf\u3067\u6c17\u306b\u306a\u308b\u3053\u3068\u3092\u307e\u3068\u3081\u3066\u3054\u76f8\u8ac7\u3044\u305f\u3060\u3051\u307e\u3059\u3002<\/p>\n\n\n
    \n

    \u95a2\u9023\u8a18\u4e8b\uff5c\u7af9\u5185\u5185\u79d1\u5c0f\u5150\u79d1\u533b\u9662\uff08\u7530\u5712\u8abf\u5e03\uff09<\/p>\n\n\n\n\n\n
    ▶<\/td>\n\u30e9\u30fc\u30e1\u30f3\u3092\u98df\u3079\u305f\u3089\u30b8\u30e7\u30ae\u30f3\u30b0\u3067\u30ea\u30bb\u30c3\u30c8\u2015\u2015\u767a\u9175\u98df\u54c1\u3068\u7761\u7720\u3067\u6574\u3048\u308b\u300c\u514d\u75ab\u30d0\u30e9\u30f3\u30b9\u7fd2\u6163\u300d\uff5c\u9031\u520a\u5973\u6027PRIME\u63b2\u8f09<\/a>
    \u672c\u8a18\u4e8b\u306e\u5143\u306b\u306a\u3063\u305f\u30e1\u30c7\u30a3\u30a2\u63b2\u8f09\u8a18\u4e8b\u3067\u3059\u3002\u514d\u75ab\u30d0\u30e9\u30f3\u30b9\u3092\u6574\u3048\u308b3\u3064\u306e\u57fa\u672c\u7fd2\u6163\u3092\u51dd\u7e2e\u3002<\/span><\/td>\n<\/tr>\n
    ▶<\/td>\n\u8840\u7cd6\u5024\u3092\u6025\u4e0a\u6607\u3055\u305b\u306a\u3044\u300c\u30d9\u30b8\u30d5\u30a1\u30fc\u30b9\u30c8\u300d\u306e\u79d1\u5b66<\/a>
    \u98df\u7269\u7e4a\u7dad\u3092\u5148\u306b\u98df\u3079\u308b\u300c\u30ab\u30fc\u30dc\u30e9\u30b9\u30c8\u300d\u306e\u52b9\u679c\u3092\u3001\u6700\u65b0\u30a8\u30d3\u30c7\u30f3\u30b9\u3067\u89e3\u8aac\u3057\u307e\u3059\u3002<\/span><\/td>\n<\/tr>\n
    ▶<\/td>\n\u5915\u98df\u306f\u5bdd\u308b3\u6642\u9593\u524d\u307e\u3067\u2015\u2015\u6642\u9593\u6804\u990a\u5b66\u3067\u6574\u3048\u308b\u4ee3\u8b1d\u3068\u7761\u7720<\/a>
    \u300c\u3044\u3064\u98df\u3079\u308b\u304b\u300d\u304c\u8178\u5185\u74b0\u5883\u3068\u7761\u7720\u306e\u8cea\u3092\u6c7a\u3081\u308b\u2015\u2015\u6642\u9593\u6804\u990a\u5b66\u306e\u6700\u65b0\u77e5\u898b\u3002<\/span><\/td>\n<\/tr>\n
    ▶<\/td>\n\u7af9\u5185\u5185\u79d1\u5c0f\u5150\u79d1\u533b\u9662 \u30d6\u30ed\u30b0\u4e00\u89a7<\/a>
    \u5c0f\u5150\u306e\u98df\u7269\u30a2\u30ec\u30eb\u30ae\u30fc\u3001\u4fbf\u79d8\u3001\u751f\u6d3b\u7fd2\u6163\u75c5\u3001\u4e88\u9632\u63a5\u7a2e\u306a\u3069\u3001\u95a2\u9023\u30c8\u30d4\u30c3\u30af\u3092\u591a\u6570\u63b2\u8f09\u3002<\/span><\/td>\n<\/tr>\n<\/table>\n<\/td>\n<\/tr>\n<\/table>\n\n\n
    \n

    \u95a2\u9023\u8a18\u4e8b\uff5c\u4e94\u826f\u4f1a\u30af\u30ea\u30cb\u30c3\u30af\u767d\u91d1\u9ad8\u8f2a\uff08\u6e2f\u533a\uff09<\/p>\n\n\n
    ▶<\/td>\n\u7cd6\u5c3f\u75c5\u5c02\u9580\u5916\u6765\u30fb\u6301\u7d9a\u8840\u7cd6\u30e2\u30cb\u30bf\u30fc\uff08CGM\uff09\u3068\u6d88\u5316\u5668\u5185\u79d1\u306e\u9023\u643a<\/a>
    \u59c9\u59b9\u9662\u306e\u767d\u91d1\u9ad8\u8f2a\u3067\u306f\u3001\u5927\u8178\u5185\u8996\u93e1\u30fb\u8178\u5185\u74b0\u5883\u8a55\u4fa1\u3068CGM\u30fbGLP-1\u6cbb\u7642\u3092\u4e00\u9023\u3067\u30ab\u30d0\u30fc\u3002\u8178\u6d3b\u3068\u7cd6\u4ee3\u8b1d\u3092\u540c\u6642\u306b\u8a3a\u307e\u3059\u3002<\/span><\/td>\n<\/tr>\n<\/table>\n<\/td>\n<\/tr>\n<\/table>\n

    \u4e94\u826f\u4f1a\u30b0\u30eb\u30fc\u30d7\u3067\u306f\u3001\u7530\u5712\u8abf\u5e03\u306e\u7af9\u5185\u5185\u79d1\u5c0f\u5150\u79d1\u533b\u9662\u3068\u6e2f\u533a\u306e\u4e94\u826f\u4f1a\u30af\u30ea\u30cb\u30c3\u30af\u767d\u91d1\u9ad8\u8f2a\u304c\u9023\u643a\u3057\u3001\u751f\u6d3b\u7fd2\u6163\u75c5\u30fb\u8178\u6d3b\u30fb\u6297\u52a0\u9f62\u3092\u591a\u89d2\u7684\u306b\u30b5\u30dd\u30fc\u30c8\u3057\u3066\u304a\u308a\u307e\u3059\u3002\u8178\u5185\u74b0\u5883\u306e\u7cbe\u5bc6\u8a55\u4fa1\u304c\u5fc5\u8981\u306a\u65b9\u306f\u3001\u59c9\u59b9\u9662\u306e\u6d88\u5316\u5668\u5185\u79d1\u5916\u6765\u3068\u30b9\u30e0\u30fc\u30ba\u306b\u9023\u643a\u3044\u305f\u3057\u307e\u3059\u3002<\/p>\n

    \u53c2\u8003\u6587\u732e<\/h2>\n
      \n
    1. Hill C, et al. The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic. Nat Rev Gastroenterol Hepatol<\/em>. 2014;11(8):506-514.<\/li>\n
    2. Furusawa Y, et al. Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells. Nature<\/em>. 2013;504(7480):446-450.<\/li>\n
    3. Wastyk HC, et al. Gut-microbiota-targeted diets modulate human immune status. Cell<\/em>. 2021;184(16):4137-4153.e14.<\/li>\n
    4. \u539a\u751f\u52b4\u50cd\u7701\u300ce-\u30d8\u30eb\u30b9\u30cd\u30c3\u30c8 \u8178\u5185\u7d30\u83cc\u3068\u5065\u5eb7\u300d\uff082024\u5e74\u95b2\u89a7\uff09<\/li>\n
    5. \u65e5\u672c\u6d88\u5316\u5668\u75c5\u5b66\u4f1a\u7de8\u300c\u6a5f\u80fd\u6027\u6d88\u5316\u7ba1\u75be\u60a3\u8a3a\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f32020\u2015\u2015\u904e\u654f\u6027\u8178\u75c7\u5019\u7fa4\uff08IBS\uff09\u300d\u5357\u6c5f\u5802.<\/li>\n<\/ol>\n

      <\/p>\n

      \n
      \n
      GORYOKAI GROUP<\/div>\n
      \u7af9\u5185\u5185\u79d1\u5c0f\u5150\u79d1\u533b\u9662<\/div>\n<\/p><\/div>\n
      \n\n\n\n
      \u5185\u79d1<\/td>\n\u5c0f\u5150\u79d1<\/td>\n\u7cd6\u5c3f\u75c5\u5185\u79d1<\/td>\n\u4ee3\u8b1d\u5185\u79d1<\/td>\n\u30a2\u30ec\u30eb\u30ae\u30fc\u79d1<\/td>\n<\/tr>\n
      \u76ae\u819a\u79d1<\/td>\n\u751f\u6d3b\u7fd2\u6163\u75c5<\/td>\n\u8a2a\u554f\u8a3a\u7642<\/td>\n\u5fc3\u7642\u5185\u79d1<\/td>\n\u5065\u5eb7\u8a3a\u65ad<\/td>\n<\/tr>\n<\/table>\n

      \u3012145-0072 \u6771\u4eac\u90fd\u5927\u7530\u533a\u7530\u5712\u8abf\u5e03\u672c\u753a40-12 \u30b3\u30f3\u30c9\u7530\u5712\u8abf\u5e03\uff12\u968e<\/p>\n

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      \u5348\u524d
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      \u5348\u5f8c
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