{"id":6340,"date":"2026-02-20T20:33:00","date_gmt":"2026-02-20T11:33:00","guid":{"rendered":"https:\/\/www.takeuchi-iin.jp\/blog\/?p=6340"},"modified":"2026-02-21T07:53:18","modified_gmt":"2026-02-20T22:53:18","slug":"%e3%80%90%e5%8c%bb%e7%99%82%e3%82%b3%e3%83%a9%e3%83%a0%e3%80%91%e5%8a%9b%e5%a3%ab%e3%83%bb%e8%8b%a5%e6%88%b8%e6%a1%9c%e3%81%95%e3%82%93%e3%81%ae%e8%a8%83%e5%a0%b1%e3%81%ab%e5%af%84%e3%81%9b%e3%81%a6","status":"publish","type":"post","link":"https:\/\/www.takeuchi-iin.jp\/blog\/%e3%80%90%e5%8c%bb%e7%99%82%e3%82%b3%e3%83%a9%e3%83%a0%e3%80%91%e5%8a%9b%e5%a3%ab%e3%83%bb%e8%8b%a5%e6%88%b8%e6%a1%9c%e3%81%95%e3%82%93%e3%81%ae%e8%a8%83%e5%a0%b1%e3%81%ab%e5%af%84%e3%81%9b%e3%81%a6\/","title":{"rendered":"\u3010\u533b\u7642\u30b3\u30e9\u30e0\u3011\u529b\u58eb\u30fb\u82e5\u6238\u685c\u3055\u3093\u306e\u8a03\u5831\u306b\u5bc4\u305b\u3066\uff5cFournier\u58ca\u75bd\u3068\u7cd6\u5c3f\u75c5\u306e\u5408\u4f75\u75c7\u3092\u5fb9\u5e95\u89e3\u8aac"},"content":{"rendered":"<p style=\"color: #888; font-size: 0.9em;\">\u521d\u7248 2025\u5e744\u670817\u65e5 \uff0f \u6700\u7d42\u66f4\u65b0 2026\u5e742\u670820\u65e5\uff5c\u7af9\u5185\u5185\u79d1\u5c0f\u5150\u79d1\u533b\u9662 \u9662\u9577 \u4e94\u85e4\u826f\u5c06<\/p>\n<p><!-- ===== \u5c0e\u5165 ===== --><\/p>\n<p>2025\u5e744\u670814\u65e5\u3001\u5927\u76f8\u64b2\u306e\u529b\u58eb\u30fb\u82e5\u6238\u685c\uff08\u308f\u304b\u3068\u3056\u304f\u3089\uff09\u525b\u3055\u3093\u304c\u3001<strong>\u5916\u9670\u90e8\u58ca\u6b7b\u6027\u7b4b\u819c\u708e\uff08Fournier\u58ca\u75bd\uff1a\u30d5\u30eb\u30cb\u30a8\u3048\u305d\uff09<\/strong>\u3068\u3044\u3046\u611f\u67d3\u75c7\u306b\u3088\u308a\u300133\u6b73\u306e\u82e5\u3055\u3067\u6025\u901d\u3055\u308c\u307e\u3057\u305f\u3002\u5fc3\u3088\u308a\u3054\u51a5\u798f\u3092\u304a\u7948\u308a\u7533\u3057\u4e0a\u3052\u307e\u3059\u3002<\/p>\n<p>\u672c\u8a18\u4e8b\u3067\u306f\u3001\u7cd6\u5c3f\u75c5\u8a3a\u7642\u3092\u5c02\u9580\u306e\u3072\u3068\u3064\u3068\u3059\u308b\u5f53\u9662\u3088\u308a\u3001Fournier\u58ca\u75bd\u306e\u75c5\u614b\u3068\u7cd6\u5c3f\u75c5\u3068\u306e\u6df1\u3044\u95a2\u9023\u6027\u3092\u89e3\u8aac\u3059\u308b\u3068\u3068\u3082\u306b\u3001<strong>\u7cd6\u5c3f\u75c5\u304c\u5f15\u304d\u8d77\u3053\u3059\u3055\u307e\u3056\u307e\u306a\u5408\u4f75\u75c7<\/strong>\u306b\u3064\u3044\u3066\u6700\u65b0\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u3092\u4ea4\u3048\u3066\u6df1\u6398\u308a\u3044\u305f\u3057\u307e\u3059\u3002\u300c\u7cd6\u5c3f\u75c5\u3068\u8a00\u308f\u308c\u305f\u3051\u308c\u3069\u75c7\u72b6\u304c\u306a\u3044\u304b\u3089\u5927\u4e08\u592b\u300d\u3068\u601d\u3063\u3066\u3044\u308b\u65b9\u306b\u3053\u305d\u3001\u305c\u3072\u6700\u5f8c\u307e\u3067\u8aad\u3093\u3067\u3044\u305f\u3060\u304d\u305f\u3044\u5185\u5bb9\u3067\u3059\u3002<\/p>\n<p><!-- ===== \u76ee\u6b21 ===== --><\/p>\n<div style=\"background: #f5f5f5; border-left: 4px solid #1a237e; border-radius: 8px; padding: 20px 25px; margin: 30px 0;\">\n<p style=\"margin: 0 0 10px 0; font-weight: bold; color: #1a237e; font-size: 1.05em;\">\u76ee\u6b21<\/p>\n<ol style=\"margin: 0; padding-left: 20px; line-height: 2.2;\">\n<li><a href=\"#sec1\" style=\"color: #1a237e; text-decoration: none;\">Fournier\u58ca\u75bd\uff08\u30d5\u30eb\u30cb\u30a8\u58ca\u75bd\uff09\u3068\u306f\uff1f<\/a><\/li>\n<li><a href=\"#sec2\" style=\"color: #1a237e; text-decoration: none;\">\u306a\u305c\u7cd6\u5c3f\u75c5\u3067Fournier\u58ca\u75bd\u306e\u30ea\u30b9\u30af\u304c\u4e0a\u304c\u308b\u306e\u304b<\/a><\/li>\n<li><a href=\"#sec3\" style=\"color: #1a237e; text-decoration: none;\">\u82e5\u6238\u685c\u3055\u3093\u3068\u529b\u58eb\u306e\u7cd6\u5c3f\u75c5\u30ea\u30b9\u30af<\/a><\/li>\n<li><a href=\"#sec4\" style=\"color: #1a237e; text-decoration: none;\">SGLT2\u963b\u5bb3\u85ac\u3068Fournier\u58ca\u75bd \u2500\u2500 FDA\u8b66\u544a\u306e\u610f\u5473<\/a><\/li>\n<li><a href=\"#sec5\" style=\"color: #1a237e; text-decoration: none;\">\u7cd6\u5c3f\u75c5\u306e\u5408\u4f75\u75c7\u3092\u77e5\u308b \u2500\u2500 \u306a\u305c\u300c\u6c88\u9ed9\u306e\u75c5\u300d\u306f\u6016\u3044\u306e\u304b<\/a><\/li>\n<li><a href=\"#sec6\" style=\"color: #1a237e; text-decoration: none;\">\u4e09\u5927\u5408\u4f75\u75c7 \u2500\u2500 \u300c\u3057\u30fb\u3081\u30fb\u3058\u300d\u306e\u899a\u3048\u65b9<\/a><\/li>\n<li><a href=\"#sec7\" style=\"color: #1a237e; text-decoration: none;\">\u5927\u8840\u7ba1\u5408\u4f75\u75c7 \u2500\u2500 \u300c\u3048\u30fb\u306e\u30fb\u304d\u300d\u306e\u899a\u3048\u65b9<\/a><\/li>\n<li><a href=\"#sec8\" style=\"color: #1a237e; text-decoration: none;\">\u611f\u67d3\u75c7\u30ea\u30b9\u30af\u306e\u5897\u5927 \u2500\u2500 Fournier\u58ca\u75bd\u3082\u305d\u306e\u4e00\u3064<\/a><\/li>\n<li><a href=\"#sec9\" style=\"color: #1a237e; text-decoration: none;\">\u7cd6\u5c3f\u75c5\u5408\u4f75\u75c7\u3092\u9632\u3050\u305f\u3081\u306e\u8840\u7cd6\u7ba1\u7406\u76ee\u6a19<\/a><\/li>\n<li><a href=\"#sec10\" style=\"color: #1a237e; text-decoration: none;\">\u5f53\u9662\u3067\u3067\u304d\u308b\u3053\u3068 \u2500\u2500 \u5305\u62ec\u7684\u306a\u7cd6\u5c3f\u75c5\u30b5\u30dd\u30fc\u30c8<\/a><\/li>\n<li><a href=\"#sec11\" style=\"color: #1a237e; text-decoration: none;\">FAQ\uff08\u3088\u304f\u3042\u308b\u3054\u8cea\u554f\uff09<\/a><\/li>\n<li><a href=\"#ref\" style=\"color: #1a237e; text-decoration: none;\">\u53c2\u8003\u6587\u732e<\/a><\/li>\n<\/ol>\n<\/div>\n<p><!-- ===== 1. Fournier\u58ca\u75bd\u3068\u306f ===== --><\/p>\n<h2 id=\"sec1\" style=\"color: #1a237e; border-left: 5px solid #1a237e; padding-left: 12px; margin-top: 45px;\">1. Fournier\u58ca\u75bd\uff08\u30d5\u30eb\u30cb\u30a8\u58ca\u75bd\uff09\u3068\u306f\uff1f<\/h2>\n<p>Fournier\u58ca\u75bd\uff08Fournier&#8217;s gangrene\uff09\u306f\u3001<strong>\u5916\u9670\u90e8\u30fb\u809b\u9580\u5468\u56f2\u30fb\u4f1a\u9670\u90e8\uff08\u80a1\u306e\u4ed8\u3051\u6839\u5468\u8fba\uff09\u306e\u76ae\u4e0b\u7d44\u7e54\u3084\u7b4b\u819c\u304c\u6025\u901f\u306b\u58ca\u6b7b\u3059\u308b\u3001\u6975\u3081\u3066\u91cd\u7be4\u306a\u611f\u67d3\u75c7<\/strong>\u3067\u3059\u30021883\u5e74\u306b\u30d5\u30e9\u30f3\u30b9\u306e\u6027\u75c5\u5b66\u8005Jean Alfred Fournier\u304c\u5831\u544a\u3057\u305f\u3053\u3068\u306b\u7531\u6765\u3057\u307e\u3059\u3002<\/p>\n<p><!-- \u30e1\u30ab\u30cb\u30ba\u30e0\u56f3\u89e3\u30dc\u30c3\u30af\u30b9\uff08\u7d2b\uff09 --><\/p>\n<div style=\"background: linear-gradient(135deg, #f3e5f5, #ede7f6); border: 2px solid #7e57c2; border-radius: 10px; padding: 22px; margin: 20px 0;\">\n<p style=\"font-weight: bold; color: #4a148c; margin: 0 0 12px 0; font-size: 1.05em;\">Fournier\u58ca\u75bd\u306e\u9032\u884c\u30e1\u30ab\u30cb\u30ba\u30e0<\/p>\n<p style=\"margin: 0 0 8px 0;\"><span style=\"display: inline-block; background: #7e57c2; color: white; border-radius: 50%; width: 24px; height: 24px; text-align: center; line-height: 24px; font-size: 0.8em; margin-right: 6px;\">1<\/span> \u5c0f\u3055\u306a\u76ae\u819a\u306e\u50b7\u30fb\u5c3f\u8def\u611f\u67d3\u30fb\u809b\u9580\u5468\u56f2\u81bf\u760d\u306a\u3069\u304c<strong>\u611f\u67d3\u306e\u5165\u308a\u53e3<\/strong>\uff08\u30a8\u30f3\u30c8\u30ea\u30fc\u30dd\u30a4\u30f3\u30c8\uff09\u3068\u306a\u308b<\/p>\n<p style=\"margin: 0 0 8px 0;\"><span style=\"display: inline-block; background: #7e57c2; color: white; border-radius: 50%; width: 24px; height: 24px; text-align: center; line-height: 24px; font-size: 0.8em; margin-right: 6px;\">2<\/span> \u5acc\u6c17\u6027\u83cc\uff08Bacteroides\u306a\u3069\uff09\u3068\u597d\u6c17\u6027\u83cc\uff08E. coli\u306a\u3069\uff09\u306e<strong>\u6df7\u5408\u611f\u67d3<\/strong>\u304c\u6210\u7acb<\/p>\n<p style=\"margin: 0 0 8px 0;\"><span style=\"display: inline-block; background: #7e57c2; color: white; border-radius: 50%; width: 24px; height: 24px; text-align: center; line-height: 24px; font-size: 0.8em; margin-right: 6px;\">3<\/span> \u7d30\u83cc\u304c\u7523\u751f\u3059\u308b\u6bd2\u7d20\u3084\u30ac\u30b9\u306b\u3088\u308a<strong>\u7b4b\u819c\u306b\u6cbf\u3063\u3066\u58ca\u6b7b\u304c\u6025\u901f\u306b\u62e1\u5927<\/strong>\uff081\u6642\u9593\u306b2\uff5e3cm\u306e\u901f\u5ea6\u3067\u9032\u884c\u3059\u308b\u3053\u3068\u3082\uff09<\/p>\n<p style=\"margin: 0 0 8px 0;\"><span style=\"display: inline-block; background: #7e57c2; color: white; border-radius: 50%; width: 24px; height: 24px; text-align: center; line-height: 24px; font-size: 0.8em; margin-right: 6px;\">4<\/span> \u9589\u9396\u6027\u52d5\u8108\u708e\uff08\u672b\u68a2\u8840\u7ba1\u306e\u9589\u585e\uff09\u3068\u76ae\u819a\u306e\u58ca\u75bd\u304c\u751f\u3058\u3001<strong>\u6557\u8840\u75c7\u30fb\u591a\u81d3\u5668\u4e0d\u5168<\/strong>\u3078\u9032\u5c55<\/p>\n<p style=\"margin: 0; color: #666; font-size: 0.9em;\">\u203b80%\u4ee5\u4e0a\u304c\u8907\u6570\u83cc\u7a2e\u306b\u3088\u308b\u6df7\u5408\u611f\u67d3\uff08polymicrobial infection\uff09\u3067\u3059<\/p>\n<\/div>\n<p><!-- \u8b66\u544a\u30dc\u30c3\u30af\u30b9\uff08\u8d64\uff09 --><\/p>\n<div style=\"background: #fff5f5; border: 2px solid #e53935; border-radius: 10px; padding: 22px; margin: 20px 0;\">\n<p style=\"font-weight: bold; color: #c62828; margin: 0 0 10px 0; font-size: 1.05em;\">Fournier\u58ca\u75bd\u306e\u75ab\u5b66\u30c7\u30fc\u30bf\uff08\u6700\u65b0\u30a8\u30d3\u30c7\u30f3\u30b9\uff09<\/p>\n<table style=\"width: 100%; border-collapse: collapse; font-size: 0.95em;\">\n<tr style=\"border-bottom: 1px solid #e0e0e0;\">\n<td style=\"padding: 8px 10px; font-weight: bold; width: 40%;\">\u81f4\u6b7b\u7387<\/td>\n<td style=\"padding: 8px 10px;\">\u7d0420.4%\uff08\u91cd\u75c7\u4f8b\u3067\u306f70%\u8d85\uff09<br \/><span style=\"color: #888; font-size: 0.85em;\">Shet P, et al. Surg Infect. 2024; PMID: 38625013<\/span><\/td>\n<\/tr>\n<tr style=\"border-bottom: 1px solid #e0e0e0;\">\n<td style=\"padding: 8px 10px; font-weight: bold;\">\u597d\u767a\u5e74\u9f62<\/td>\n<td style=\"padding: 8px 10px;\">50\uff5e70\u4ee3\u7537\u6027\u304c\u4e2d\u5fc3\uff08\u82e5\u5e74\u4f8b\u3082\u3042\u308a\uff09<\/td>\n<\/tr>\n<tr style=\"border-bottom: 1px solid #e0e0e0;\">\n<td style=\"padding: 8px 10px; font-weight: bold;\">\u7537\u5973\u6bd4<\/td>\n<td style=\"padding: 8px 10px;\">\u7d0410:1\u3067\u7537\u6027\u306b\u591a\u3044\uff08\u305f\u3060\u3057\u5973\u6027\u306e\u81f4\u6b7b\u7387\u306f\u3088\u308a\u9ad8\u3044\uff09<\/td>\n<\/tr>\n<tr style=\"border-bottom: 1px solid #e0e0e0;\">\n<td style=\"padding: 8px 10px; font-weight: bold;\">\u6700\u591a\u306e\u57fa\u790e\u75be\u60a3<\/td>\n<td style=\"padding: 8px 10px;\"><strong style=\"color: #c62828;\">\u7cd6\u5c3f\u75c5\uff0840\uff5e62%\uff09<\/strong><\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 8px 10px; font-weight: bold;\">\u6cbb\u7642<\/td>\n<td style=\"padding: 8px 10px;\">\u7dca\u6025\u5916\u79d1\u7684\u30c7\u30d6\u30ea\u30fc\u30c9\u30de\u30f3\uff0b\u5e83\u57df\u6297\u83cc\u85ac\uff0b\u96c6\u4e2d\u7ba1\u7406<\/td>\n<\/tr>\n<\/table>\n<\/div>\n<p><!-- ===== 2. \u306a\u305c\u7cd6\u5c3f\u75c5\u3067\u30ea\u30b9\u30af\u304c\u4e0a\u304c\u308b\u304b ===== --><\/p>\n<h2 id=\"sec2\" style=\"color: #1a237e; border-left: 5px solid #1a237e; padding-left: 12px; margin-top: 45px;\">2. \u306a\u305c\u7cd6\u5c3f\u75c5\u3067Fournier\u58ca\u75bd\u306e\u30ea\u30b9\u30af\u304c\u4e0a\u304c\u308b\u306e\u304b<\/h2>\n<p>Fournier\u58ca\u75bd\u306e\u60a3\u8005\u306e\u3046\u3061<strong>40\uff5e62%\u306b\u7cd6\u5c3f\u75c5<\/strong>\u304c\u3042\u308b\u3068\u3055\u308c\u3001\u7cd6\u5c3f\u75c5\u306f\u672c\u75be\u60a3\u306e\u6700\u5927\u306e\u30ea\u30b9\u30af\u56e0\u5b50\u3067\u3059\u30022024\u5e74\u306e\u30b7\u30b9\u30c6\u30de\u30c6\u30a3\u30c3\u30af\u30ec\u30d3\u30e5\u30fc\uff083,646\u75c7\u4f8b\uff09\u3067\u3082\u3001\u6b7b\u4ea1\u4f8b\u306b\u304a\u3051\u308b\u6700\u591a\u306e\u4f75\u5b58\u75be\u60a3\u306f\u7cd6\u5c3f\u75c5\u3067\u3057\u305f\u3002<\/p>\n<p><!-- \u30a8\u30d3\u30c7\u30f3\u30b9\u30dc\u30c3\u30af\u30b9\uff08\u7dd1\uff09 --><\/p>\n<div style=\"background: #e8f5e9; border: 2px solid #43a047; border-radius: 10px; padding: 22px; margin: 20px 0;\">\n<p style=\"font-weight: bold; color: #2e7d32; margin: 0 0 12px 0; font-size: 1.05em;\">\u7cd6\u5c3f\u75c5\u304cFournier\u58ca\u75bd\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u308b4\u3064\u306e\u30e1\u30ab\u30cb\u30ba\u30e0<\/p>\n<p style=\"margin: 0 0 10px 0;\"><strong style=\"color: #2e7d32;\">1\uff09\u597d\u4e2d\u7403\u6a5f\u80fd\u306e\u4f4e\u4e0b<\/strong><br \/>\n\u9ad8\u8840\u7cd6\u306b\u3088\u308a\u597d\u4e2d\u7403\u306e\u904a\u8d70\u80fd\u30fb\u8caa\u98df\u80fd\u30fb\u6bba\u83cc\u80fd\u304c\u4f4e\u4e0b\u3057\u3001\u7d30\u83cc\u306b\u5bfe\u3059\u308b\u521d\u671f\u9632\u5fa1\u304c\u5f31\u307e\u308a\u307e\u3059\u3002<\/p>\n<p style=\"margin: 0 0 10px 0;\"><strong style=\"color: #2e7d32;\">2\uff09\u672b\u68a2\u8840\u6d41\u969c\u5bb3\uff08\u5fae\u5c0f\u8840\u7ba1\u969c\u5bb3\uff09<\/strong><br \/>\n\u7cd6\u5c3f\u75c5\u306b\u4f34\u3046\u52d5\u8108\u786c\u5316\u3084\u5fae\u5c0f\u8840\u7ba1\u969c\u5bb3\u306b\u3088\u308a\u4f1a\u9670\u90e8\u306e\u8840\u6d41\u304c\u4f4e\u4e0b\u3057\u3001\u611f\u67d3\u5de3\u3078\u306e\u514d\u75ab\u7d30\u80de\u306e\u52d5\u54e1\u3068\u6297\u83cc\u85ac\u306e\u5230\u9054\u304c\u59a8\u3052\u3089\u308c\u307e\u3059\u3002<\/p>\n<p style=\"margin: 0 0 10px 0;\"><strong style=\"color: #2e7d32;\">3\uff09\u9ad8\u8840\u7cd6\u74b0\u5883\u3067\u306e\u7d30\u83cc\u5897\u6b96\u4fc3\u9032<\/strong><br \/>\n\u8840\u7cd6\u5024\u304c\u9ad8\u3044\u72b6\u614b\u3067\u306f\u7d44\u7e54\u4e2d\u306e\u30b0\u30eb\u30b3\u30fc\u30b9\u6fc3\u5ea6\u3082\u4e0a\u6607\u3057\u3001\u7d30\u83cc\u306b\u3068\u3063\u3066\u683c\u597d\u306e\u57f9\u5730\u3068\u306a\u308a\u307e\u3059\u3002\u5c3f\u4e2d\u306e\u30b0\u30eb\u30b3\u30fc\u30b9\u3082\u7d30\u83cc\u306e\u6804\u990a\u6e90\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n<p style=\"margin: 0;\"><strong style=\"color: #2e7d32;\">4\uff09\u7cd6\u5c3f\u75c5\u6027\u795e\u7d4c\u969c\u5bb3\u306b\u3088\u308b\u611f\u899a\u4f4e\u4e0b<\/strong><br \/>\n\u4f1a\u9670\u90e8\u3084\u4e0b\u80a2\u306e\u611f\u899a\u304c\u920d\u304f\u306a\u308a\u3001\u5c0f\u3055\u306a\u50b7\u3084\u7570\u5e38\u3092\u81ea\u899a\u3057\u306b\u304f\u304f\u3001\u53d7\u8a3a\u304c\u9045\u308c\u304c\u3061\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n<\/div>\n<p>\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u3067\u306f\u3001<strong>\u7cd6\u5c3f\u75c5\u60a3\u8005\u306eFournier\u58ca\u75bd\u306b\u3088\u308b\u6b7b\u4ea1\u30ea\u30b9\u30af\u306f\u975e\u7cd6\u5c3f\u75c5\u60a3\u8005\u306b\u6bd4\u3079\u6709\u610f\u306b\u9ad8\u3044<\/strong>\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\uff08RR 0.72, 95%CI 0.59-0.89; El-Qushayri AE, et al. Int J Infect Dis. 2020\uff09\u3002<\/p>\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" src=\"https:\/\/www.takeuchi-iin.jp\/blog\/wp-content\/uploads\/2026\/02\/1cafcb1be3c42eeab3b656fdab1af28f.jpg\" alt=\"\" width=\"710\" height=\"800\" class=\"alignnone size-full wp-image-3403\" \/><\/figure>\n<p><!-- ===== 3. \u82e5\u6238\u685c\u3055\u3093\u3068\u529b\u58eb\u306e\u7cd6\u5c3f\u75c5\u30ea\u30b9\u30af ===== --><\/p>\n<h2 id=\"sec3\" style=\"color: #1a237e; border-left: 5px solid #1a237e; padding-left: 12px; margin-top: 45px;\">3. \u82e5\u6238\u685c\u3055\u3093\u3068\u529b\u58eb\u306e\u7cd6\u5c3f\u75c5\u30ea\u30b9\u30af<\/h2>\n<p>\u5831\u9053\u3067\u306f\u82e5\u6238\u685c\u3055\u3093\u304c\u7cd6\u5c3f\u75c5\u3067\u3042\u3063\u305f\u304b\u306f\u660e\u8a00\u3055\u308c\u3066\u3044\u307e\u305b\u3093\u304c\u3001\u529b\u58eb\u306e\u8077\u696d\u7279\u6027\u304b\u3089<strong>\u7cd6\u5c3f\u75c5\u3084\u7cd6\u5c3f\u75c5\u4e88\u5099\u7fa4\u3092\u62b1\u3048\u3066\u3044\u305f\u53ef\u80fd\u6027\u306f\u5426\u5b9a\u3067\u304d\u307e\u305b\u3093<\/strong>\u3002<\/p>\n<p><!-- \u30dd\u30a4\u30f3\u30c8\u30dc\u30c3\u30af\u30b9\uff08\u9752\uff09 --><\/p>\n<div style=\"background: #e3f2fd; border: 2px solid #1e88e5; border-radius: 10px; padding: 22px; margin: 20px 0;\">\n<p style=\"font-weight: bold; color: #1565c0; margin: 0 0 12px 0; font-size: 1.05em;\">\u529b\u58eb\u306e\u7cd6\u5c3f\u75c5\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u7406\u7531<\/p>\n<p style=\"margin: 0 0 8px 0;\"><strong>\u4f53\u683c\u9762\uff1a<\/strong>\u5927\u91cf\u306e\u30ab\u30ed\u30ea\u30fc\u6442\u53d6\u3068\u5185\u81d3\u8102\u80aa\u84c4\u7a4d\u306b\u3088\u308a\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u304c\u9ad8\u307e\u308a\u3084\u3059\u3044\u74b0\u5883\u306b\u3042\u308a\u307e\u3059\u3002BMI 35\u4ee5\u4e0a\u304c\u73cd\u3057\u304f\u306a\u304f\u3001\u30e1\u30bf\u30dc\u30ea\u30c3\u30af\u30b7\u30f3\u30c9\u30ed\u30fc\u30e0\u306e\u57fa\u6e96\u3092\u8d85\u3048\u308b\u529b\u58eb\u306f\u5c11\u306a\u304f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n<p style=\"margin: 0 0 8px 0;\"><strong>\u98df\u7fd2\u6163\uff1a<\/strong>\u9ad8\u30ab\u30ed\u30ea\u30fc\u306e\u3061\u3083\u3093\u3053\u934b\u30921\u65e52\u98df\u306b\u307e\u3068\u3081\u3066\u6442\u53d6\u3059\u308b\u30b9\u30bf\u30a4\u30eb\u306f\u3001\u98df\u5f8c\u306e\u6025\u6fc0\u306a\u8840\u7cd6\u4e0a\u6607\uff08\u98df\u5f8c\u9ad8\u8840\u7cd6\uff09\u3092\u62db\u304d\u3084\u3059\u3044\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002<\/p>\n<p style=\"margin: 0 0 8px 0;\"><strong>\u30c7\u30fc\u30bf\uff1a<\/strong>\u76f8\u64b2\u5354\u4f1a\u306e\u5065\u5eb7\u8abf\u67fb\uff082018\u5e74\uff09\u3067\u306f\u3001\u529b\u58eb\u306e\u7d0411%\u304c\u7a7a\u8179\u6642\u8840\u7cd6\u3067\u57fa\u6e96\u5024\u3092\u8d85\u3048\u3066\u3044\u305f\u3068\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u73fe\u5f79\u4e2d\u3067\u3042\u3063\u3066\u3082\u6cb9\u65ad\u306f\u3067\u304d\u307e\u305b\u3093\u3002<\/p>\n<p style=\"margin: 0;\"><strong>\u5f15\u9000\u5f8c\u306e\u30ea\u30b9\u30af\uff1a<\/strong>\u73fe\u5f79\u6642\u4ee3\u306e\u904b\u52d5\u91cf\u304c\u6fc0\u6e1b\u3059\u308b\u5f15\u9000\u5f8c\u306b\u3001\u98df\u7fd2\u6163\u304c\u5909\u308f\u3089\u306a\u3044\u307e\u307e\u4f53\u91cd\u304c\u7dad\u6301\u3055\u308c\u308b\u3068\u30012\u578b\u7cd6\u5c3f\u75c5\u306e\u767a\u75c7\u7387\u304c\u3055\u3089\u306b\u4e0a\u6607\u3057\u307e\u3059\u3002<\/p>\n<\/div>\n<p><!-- ===== 4. SGLT2\u963b\u5bb3\u85ac ===== --><\/p>\n<h2 id=\"sec4\" style=\"color: #1a237e; border-left: 5px solid #1a237e; padding-left: 12px; margin-top: 45px;\">4. SGLT2\u963b\u5bb3\u85ac\u3068Fournier\u58ca\u75bd \u2500\u2500 FDA\u8b66\u544a\u306e\u610f\u5473<\/h2>\n<p>\u7cd6\u5c3f\u75c5\u6cbb\u7642\u306e\u73fe\u5834\u3067\u8fd1\u5e74\u5e83\u304f\u51e6\u65b9\u3055\u308c\u3066\u3044\u308b<strong>SGLT2\u963b\u5bb3\u85ac<\/strong>\uff08\u30a8\u30f3\u30d1\u30b0\u30ea\u30d5\u30ed\u30b8\u30f3\uff1a\u30b8\u30e3\u30c7\u30a3\u30a2\u30f3\u30b9\u3001\u30c0\u30d1\u30b0\u30ea\u30d5\u30ed\u30b8\u30f3\uff1a\u30d5\u30a9\u30b7\u30fc\u30ac\u3001\u30ab\u30ca\u30b0\u30ea\u30d5\u30ed\u30b8\u30f3\uff1a\u30ab\u30ca\u30b0\u30eb\u306a\u3069\uff09\u306b\u3064\u3044\u3066\u30012018\u5e748\u6708\u306b\u7c73\u56fdFDA\uff08\u98df\u54c1\u533b\u85ac\u54c1\u5c40\uff09\u304cFournier\u58ca\u75bd\u306e\u30ea\u30b9\u30af\u5897\u52a0\u306b\u95a2\u3059\u308b<strong>\u5b89\u5168\u6027\u8b66\u544a<\/strong>\u3092\u767a\u51fa\u3057\u307e\u3057\u305f\u3002<\/p>\n<p><!-- \u8b66\u544a\u30dc\u30c3\u30af\u30b9\uff08\u30aa\u30ec\u30f3\u30b8\uff09 --><\/p>\n<div style=\"background: #fff8e1; border: 2px solid #ff8f00; border-radius: 10px; padding: 22px; margin: 20px 0;\">\n<p style=\"font-weight: bold; color: #e65100; margin: 0 0 12px 0; font-size: 1.05em;\">FDA\u8b66\u544a\uff082018\u5e748\u6708\uff09\u306e\u30dd\u30a4\u30f3\u30c8<\/p>\n<p style=\"margin: 0 0 8px 0;\">2013\u5e743\u6708\uff5e2018\u5e745\u6708\u306e\u9593\u306bSGLT2\u963b\u5bb3\u85ac\u3092\u51e6\u65b9\u3055\u308c\u305f\u60a3\u8005\u3067\u3001<strong>12\u4f8b\u306eFournier\u58ca\u75bd<\/strong>\u304c\u5831\u544a\u3055\u308c\u307e\u3057\u305f\u3002\u4e00\u65b9\u3001\u904e\u53bb30\u5e74\u4ee5\u4e0a\u306e\u30c7\u30fc\u30bf\u3067\u4ed6\u306e\u7cd6\u5c3f\u75c5\u6cbb\u7642\u85ac\u3067\u306f\u308f\u305a\u304b6\u4f8b\u306b\u3068\u3069\u307e\u3063\u3066\u304a\u308a\u3001SGLT2\u963b\u5bb3\u85ac\u3068\u306e\u95a2\u9023\u304c\u793a\u5506\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<p style=\"margin: 0 0 8px 0;\">\u56fd\u5185\u3067\u30822019\u5e74\u306b\u6dfb\u4ed8\u6587\u66f8\u304c\u6539\u8a02\u3055\u308c\u3001<strong>\u300c\u91cd\u5927\u306a\u526f\u4f5c\u7528\u300d\u306e\u9805\u306bFournier\u58ca\u75bd\u304c\u8ffd\u8a18<\/strong>\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n<p style=\"margin: 0; color: #e65100;\"><strong>\u305f\u3060\u3057\uff1a<\/strong>SGLT2\u963b\u5bb3\u85ac\u306e\u5fc3\u8840\u7ba1\u30fb\u814e\u4fdd\u8b77\u52b9\u679c\u306f\u6975\u3081\u3066\u5927\u304d\u304f\u3001\u3053\u306e\u30ea\u30b9\u30af\u306e\u307f\u3092\u7406\u7531\u306b\u670d\u7528\u3092\u81ea\u5df1\u4e2d\u65ad\u3059\u308b\u3053\u3068\u306f\u63a8\u5968\u3055\u308c\u307e\u305b\u3093\u3002\u7570\u5e38\u3092\u611f\u3058\u305f\u3089\u3059\u3050\u306b\u53d7\u8a3a\u3059\u308b\u3053\u3068\u304c\u5927\u5207\u3067\u3059\u3002<\/p>\n<\/div>\n<p><!-- \u30dd\u30a4\u30f3\u30c8\u30dc\u30c3\u30af\u30b9\uff08\u9752\uff09 --><\/p>\n<div style=\"background: #e3f2fd; border: 2px solid #1e88e5; border-radius: 10px; padding: 22px; margin: 20px 0;\">\n<p style=\"font-weight: bold; color: #1565c0; margin: 0 0 12px 0; font-size: 1.05em;\">SGLT2\u963b\u5bb3\u85ac\u304cFournier\u58ca\u75bd\u3092\u5f15\u304d\u8d77\u3053\u3059\u63a8\u5b9a\u30e1\u30ab\u30cb\u30ba\u30e0<\/p>\n<p style=\"margin: 0;\">SGLT2\u963b\u5bb3\u85ac\u306f\u814e\u81d3\u3067\u306e\u30d6\u30c9\u30a6\u7cd6\u518d\u5438\u53ce\u3092\u6291\u5236\u3057\u3001\u5c3f\u4e2d\u306b\u30b0\u30eb\u30b3\u30fc\u30b9\u3092\u6392\u6cc4\u3055\u305b\u308b\u85ac\u3067\u3059\u3002\u305d\u306e\u7d50\u679c\u3001<strong>\u5c3f\u4e2d\u306e\u30b0\u30eb\u30b3\u30fc\u30b9\u6fc3\u5ea6\u304c\u4e0a\u6607<\/strong>\u3057\u3001\u5c3f\u8def\u30fb\u6027\u5668\u5468\u8fba\u3067\u7d30\u83cc\uff08\u7279\u306b\u30ab\u30f3\u30b8\u30c0\u306a\u3069\u306e\u771f\u83cc\uff09\u304c\u7e41\u6b96\u3057\u3084\u3059\u3044\u74b0\u5883\u304c\u751f\u307e\u308c\u307e\u3059\u3002\u6027\u5668\u611f\u67d3\u75c7\u304b\u3089\u4f1a\u9670\u90e8\u3078\u611f\u67d3\u304c\u6ce2\u53ca\u3059\u308b\u3068\u3001Fournier\u58ca\u75bd\u306b\u81f3\u308b\u30ea\u30b9\u30af\u304c\u3042\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<\/div>\n<p><strong>SGLT2\u963b\u5bb3\u85ac\u3092\u670d\u7528\u4e2d\u306e\u65b9\u3078\uff1a<\/strong>\u5916\u9670\u90e8\u30fb\u4f1a\u9670\u90e8\u30fb\u809b\u9580\u5468\u56f2\u306b<span style=\"color: #c62828; font-weight: bold;\">\u767a\u8d64\u30fb\u816b\u8139\u30fb\u75bc\u75db<\/span>\u304c\u3042\u308a\u3001<span style=\"color: #c62828; font-weight: bold;\">38\u2103\u4ee5\u4e0a\u306e\u767a\u71b1<\/span>\u3092\u4f34\u3046\u5834\u5408\u306f\u3001\u76f4\u3061\u306b\u533b\u7642\u6a5f\u95a2\u3092\u53d7\u8a3a\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n<p><!-- ===== 5. \u7cd6\u5c3f\u75c5\u306e\u5408\u4f75\u75c7 \u7dcf\u8ad6 ===== --><\/p>\n<h2 id=\"sec5\" style=\"color: #1a237e; border-left: 5px solid #1a237e; padding-left: 12px; margin-top: 45px;\">5. \u7cd6\u5c3f\u75c5\u306e\u5408\u4f75\u75c7\u3092\u77e5\u308b \u2500\u2500 \u306a\u305c\u300c\u6c88\u9ed9\u306e\u75c5\u300d\u306f\u6016\u3044\u306e\u304b<\/h2>\n<p>\u7cd6\u5c3f\u75c5\u306f\u300c\u30b5\u30a4\u30ec\u30f3\u30c8\u30ad\u30e9\u30fc\uff08\u6c88\u9ed9\u306e\u6bba\u3057\u5c4b\uff09\u300d\u3068\u547c\u3070\u308c\u307e\u3059\u3002<strong>\u8840\u7cd6\u5024\u304c\u9ad8\u3044\u3053\u3068\u81ea\u4f53\u3067\u306f\u3001\u3088\u307b\u3069\u306e\u91cd\u75c7\u3067\u306a\u3044\u9650\u308a\u81ea\u899a\u75c7\u72b6\u304c\u307b\u3068\u3093\u3069\u306a\u3044<\/strong>\u304b\u3089\u3067\u3059\u3002\u3057\u304b\u3057\u3001\u9ad8\u8840\u7cd6\u72b6\u614b\u304c\u5e74\u5358\u4f4d\u3067\u6301\u7d9a\u3059\u308b\u3068\u3001\u5168\u8eab\u306e\u8840\u7ba1\u3084\u795e\u7d4c\u3092\u9759\u304b\u306b\u50b7\u3064\u3051\u3001\u3084\u304c\u3066\u6df1\u523b\u306a\u81d3\u5668\u969c\u5bb3\uff08\u5408\u4f75\u75c7\uff09\u3092\u5f15\u304d\u8d77\u3053\u3057\u307e\u3059\u3002<\/p>\n<p><!-- \u91cd\u8981\u30dc\u30c3\u30af\u30b9\uff08\u8d64\/\u30d4\u30f3\u30af\uff09 --><\/p>\n<div style=\"background: #fce4ec; border: 2px solid #e91e63; border-radius: 10px; padding: 22px; margin: 20px 0;\">\n<p style=\"font-weight: bold; color: #ad1457; margin: 0 0 12px 0; font-size: 1.1em;\">\u7cd6\u5c3f\u75c5\u306e\u5408\u4f75\u75c7\u306f\u5927\u304d\u304f3\u3064\u306e\u30ab\u30c6\u30b4\u30ea\u30fc\u306b\u5206\u3051\u3089\u308c\u307e\u3059<\/p>\n<table style=\"width: 100%; border-collapse: collapse; font-size: 0.95em;\">\n<tr style=\"background: #f8bbd0;\">\n<th style=\"padding: 10px; text-align: left;\">\u30ab\u30c6\u30b4\u30ea\u30fc<\/th>\n<th style=\"padding: 10px; text-align: left;\">\u969c\u5bb3\u3055\u308c\u308b\u8840\u7ba1<\/th>\n<th style=\"padding: 10px; text-align: left;\">\u4ee3\u8868\u75be\u60a3<\/th>\n<th style=\"padding: 10px; text-align: left;\">\u899a\u3048\u65b9<\/th>\n<\/tr>\n<tr style=\"border-bottom: 1px solid #e0e0e0;\">\n<td style=\"padding: 10px;\"><strong>\u7d30\u5c0f\u8840\u7ba1\u5408\u4f75\u75c7<\/strong><\/td>\n<td style=\"padding: 10px;\">\u6bdb\u7d30\u8840\u7ba1\u30fb\u5c0f\u8840\u7ba1<\/td>\n<td style=\"padding: 10px;\">\u7db2\u819c\u75c7\u30fb\u814e\u75c7\u30fb\u795e\u7d4c\u969c\u5bb3<\/td>\n<td style=\"padding: 10px; color: #ad1457; font-weight: bold;\">\u300c\u3057\u30fb\u3081\u30fb\u3058\u300d<\/td>\n<\/tr>\n<tr style=\"border-bottom: 1px solid #e0e0e0;\">\n<td style=\"padding: 10px;\"><strong>\u5927\u8840\u7ba1\u5408\u4f75\u75c7<\/strong><\/td>\n<td style=\"padding: 10px;\">\u592a\u3044\u52d5\u8108<\/td>\n<td style=\"padding: 10px;\">\u58ca\u75bd\u30fb\u8133\u5352\u4e2d\u30fb\u865a\u8840\u6027\u5fc3\u75be\u60a3<\/td>\n<td style=\"padding: 10px; color: #ad1457; font-weight: bold;\">\u300c\u3048\u30fb\u306e\u30fb\u304d\u300d<\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 10px;\"><strong>\u305d\u306e\u4ed6<\/strong><\/td>\n<td style=\"padding: 10px;\">\u514d\u75ab\u7cfb\u5168\u822c<\/td>\n<td style=\"padding: 10px;\">\u611f\u67d3\u75c7\u30fb\u6b6f\u5468\u75c5\u30fb\u304c\u3093\u30fb\u8a8d\u77e5\u75c7<\/td>\n<td style=\"padding: 10px;\">\u2500<\/td>\n<\/tr>\n<\/table>\n<\/div>\n<p>\u5408\u4f75\u75c7\u306f<strong>\u4e0d\u53ef\u9006\u7684<\/strong>\uff08\u5143\u306b\u623b\u3089\u306a\u3044\uff09\u306a\u3082\u306e\u304c\u591a\u304f\u3001\u75c7\u72b6\u304c\u51fa\u3066\u304b\u3089\u6cbb\u7642\u3092\u59cb\u3081\u3066\u3082\u300c\u6642\u3059\u3067\u306b\u9045\u3057\u300d\u3068\u3044\u3046\u3053\u3068\u304c\u73cd\u3057\u304f\u3042\u308a\u307e\u305b\u3093\u3002\u3060\u304b\u3089\u3053\u305d\u3001<strong>\u75c7\u72b6\u304c\u306a\u3044\u3046\u3061\u304b\u3089\u306e\u4e88\u9632\u3068\u5b9a\u671f\u691c\u67fb<\/strong>\u304c\u6975\u3081\u3066\u91cd\u8981\u3067\u3059\u3002<\/p>\n<p><!-- ===== 6. \u4e09\u5927\u5408\u4f75\u75c7 ===== --><\/p>\n<h2 id=\"sec6\" style=\"color: #1a237e; border-left: 5px solid #1a237e; padding-left: 12px; margin-top: 45px;\">6. \u4e09\u5927\u5408\u4f75\u75c7 \u2500\u2500\u300c\u3057\u30fb\u3081\u30fb\u3058\u300d\u306e\u899a\u3048\u65b9<\/h2>\n<p>\u7cd6\u5c3f\u75c5\u306e\u4e09\u5927\u5408\u4f75\u75c7\u306f\u3001\u982d\u6587\u5b57\u3092\u3068\u3063\u3066<strong>\u300c\u3057\u30fb\u3081\u30fb\u3058\u300d<\/strong>\u3068\u899a\u3048\u307e\u3059\u3002\u3044\u305a\u308c\u3082<strong>\u7d30\u5c0f\u8840\u7ba1\u969c\u5bb3\uff08microvascular complications\uff09<\/strong>\u304c\u539f\u56e0\u3067\u3059\u3002<\/p>\n<p><!-- \u3057\u3093\u3051\u3044\uff1a\u795e\u7d4c\u969c\u5bb3 --><\/p>\n<h3 style=\"color: #00695c; margin-top: 30px;\">\u3057\uff1a\u7cd6\u5c3f\u75c5\u6027\u795e\u7d4c\u969c\u5bb3\uff08Diabetic Neuropathy\uff09<\/h3>\n<div style=\"background: #e8f5e9; border: 2px solid #43a047; border-radius: 10px; padding: 22px; margin: 15px 0;\">\n<p style=\"font-weight: bold; color: #2e7d32; margin: 0 0 10px 0;\">\u4e09\u5927\u5408\u4f75\u75c7\u306e\u4e2d\u3067\u6700\u3082\u65e9\u671f\u306b\u51fa\u73fe<\/p>\n<p style=\"margin: 0 0 8px 0;\"><strong>\u75c7\u72b6\uff1a<\/strong>\u624b\u8db3\u306e\u3057\u3073\u308c\u30fb\u30d4\u30ea\u30d4\u30ea\u611f\uff08\u7279\u306b\u8db3\u5148\u304b\u3089\uff09\u3001\u8db3\u306e\u611f\u899a\u4f4e\u4e0b\u3001\u3053\u3080\u3089\u8fd4\u308a\u3001\u7acb\u3061\u304f\u3089\u307f\uff08\u8d77\u7acb\u6027\u4f4e\u8840\u5727\uff09\u3001\u767a\u6c57\u7570\u5e38\u3001\u4fbf\u79d8\u30fb\u4e0b\u75e2\u306e\u4ea4\u66ff\u3001\u52c3\u8d77\u969c\u5bb3\uff08ED\uff09<\/p>\n<p style=\"margin: 0 0 8px 0;\"><strong>\u6016\u3044\u70b9\uff1a<\/strong>\u8db3\u306e\u611f\u899a\u304c\u920d\u304f\u306a\u308b\u3068\u3001\u50b7\u3084\u3084\u3051\u3069\u306b\u6c17\u3065\u304b\u305a\u3001\u7cd6\u5c3f\u75c5\u8db3\u75c5\u5909\uff08\u58ca\u75bd\uff09\u3084<strong>Fournier\u58ca\u75bd\u306e\u30ea\u30b9\u30af<\/strong>\u306b\u3082\u3064\u306a\u304c\u308a\u307e\u3059\u3002<\/p>\n<p style=\"margin: 0;\"><strong>\u691c\u67fb\uff1a<\/strong>\u30a2\u30ad\u30ec\u30b9\u8171\u53cd\u5c04\u3001\u632f\u52d5\u899a\u691c\u67fb\u3001\u795e\u7d4c\u4f1d\u5c0e\u901f\u5ea6\u691c\u67fb\u3001CVR-R\uff08\u5fc3\u96fb\u56f3R-R\u9593\u9694\u5909\u52d5\u4fc2\u6570\uff09<\/p>\n<\/div>\n<p><!-- \u3081\uff1a\u7db2\u819c\u75c7 --><\/p>\n<h3 style=\"color: #00695c; margin-top: 30px;\">\u3081\uff1a\u7cd6\u5c3f\u75c5\u7db2\u819c\u75c7\uff08Diabetic Retinopathy\uff09<\/h3>\n<div style=\"background: #e8f5e9; border: 2px solid #43a047; border-radius: 10px; padding: 22px; margin: 15px 0;\">\n<p style=\"font-weight: bold; color: #2e7d32; margin: 0 0 10px 0;\">\u65e5\u672c\u306e\u6210\u4eba\u306e\u4e2d\u9014\u5931\u660e\u539f\u56e0 \u7b2c2\u4f4d<\/p>\n<p style=\"margin: 0 0 8px 0;\"><strong>\u75c7\u72b6\uff1a<\/strong>\u521d\u671f\u306f<strong>\u307e\u3063\u305f\u304f\u7121\u75c7\u72b6<\/strong>\u3002\u9032\u884c\u3059\u308b\u3068\u98db\u868a\u75c7\u3001\u8996\u529b\u4f4e\u4e0b\u3001\u6700\u60aa\u306e\u5834\u5408\u306f\u5931\u660e\u306b\u81f3\u308a\u307e\u3059\u3002<\/p>\n<p style=\"margin: 0 0 8px 0;\"><strong>\u9032\u884c\u6bb5\u968e\uff1a<\/strong>\u5358\u7d14\u7db2\u819c\u75c7 \u2192 \u5897\u6b96\u524d\u7db2\u819c\u75c7 \u2192 \u5897\u6b96\u7db2\u819c\u75c7\u3002\u5897\u6b96\u7db2\u819c\u75c7\u307e\u3067\u9032\u884c\u3059\u308b\u3068\u3001\u785d\u5b50\u4f53\u51fa\u8840\u3084\u7db2\u819c\u5265\u96e2\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u307e\u308a\u307e\u3059\u3002<\/p>\n<p style=\"margin: 0 0 8px 0;\"><strong>\u6016\u3044\u70b9\uff1a<\/strong>\u521d\u671f\u306f\u81ea\u899a\u75c7\u72b6\u304c\u306a\u3044\u305f\u3081\u3001\u5b9a\u671f\u7684\u306a\u773c\u79d1\u53d7\u8a3a\u3092\u6020\u308b\u3068\u6c17\u3065\u3044\u305f\u3068\u304d\u306b\u306f\u624b\u9045\u308c\u306b\u306a\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n<p style=\"margin: 0;\"><strong>\u691c\u67fb\u983b\u5ea6\uff1a<\/strong>\u7cd6\u5c3f\u75c5\u8a3a\u65ad\u5f8c\u306f<strong>\u534a\u5e74\u306b1\u56de<\/strong>\u306e\u773c\u5e95\u691c\u67fb\u304c\u63a8\u5968\u3055\u308c\u307e\u3059\uff08\u7cd6\u5c3f\u75c5\u8a3a\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f32024\uff09\u3002<\/p>\n<\/div>\n<p><!-- \u3058\uff1a\u814e\u75c7 --><\/p>\n<h3 style=\"color: #00695c; margin-top: 30px;\">\u3058\uff1a\u7cd6\u5c3f\u75c5\u6027\u814e\u75c7\uff08Diabetic Nephropathy\uff09<\/h3>\n<div style=\"background: #e8f5e9; border: 2px solid #43a047; border-radius: 10px; padding: 22px; margin: 15px 0;\">\n<p style=\"font-weight: bold; color: #2e7d32; margin: 0 0 10px 0;\">\u65e5\u672c\u306e\u900f\u6790\u5c0e\u5165\u539f\u56e0 \u7b2c1\u4f4d<\/p>\n<p style=\"margin: 0 0 8px 0;\"><strong>\u75c7\u72b6\uff1a<\/strong>\u521d\u671f\u306f\u7121\u75c7\u72b6\u3002\u9032\u884c\u3059\u308b\u3068\u3080\u304f\u307f\u3001\u5026\u6020\u611f\u3001\u8ca7\u8840\u304c\u51fa\u73fe\u3057\u3001\u6700\u7d42\u7684\u306b\u306f<strong>\u4eba\u5de5\u900f\u6790<\/strong>\u304c\u5fc5\u8981\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n<p style=\"margin: 0 0 8px 0;\"><strong>\u75c5\u671f\u5206\u985e\uff082023\u5e74\u6539\u8a02\uff09\uff1a<\/strong>\u7b2c1\u671f\uff08\u814e\u75c7\u524d\u671f\uff09 \u2192 \u7b2c2\u671f\uff08\u65e9\u671f\u814e\u75c7\u671f\uff09 \u2192 \u7b2c3\u671f\uff08\u9855\u6027\u814e\u75c7\u671f\uff09 \u2192 \u7b2c4\u671f\uff08\u814e\u4e0d\u5168\u671f\uff09 \u2192 \u7b2c5\u671f\uff08\u900f\u6790\u7642\u6cd5\u671f\uff09<\/p>\n<p style=\"margin: 0 0 8px 0;\"><strong>\u65e9\u671f\u767a\u898b\u306e\u9375\uff1a<\/strong>\u5c3f\u4e2d\u5fae\u91cf\u30a2\u30eb\u30d6\u30df\u30f3\u691c\u67fb\uff08\u5c3f\u30a2\u30eb\u30d6\u30df\u30f3\/\u30af\u30ec\u30a2\u30c1\u30cb\u30f3\u6bd4\uff1aUACR\uff09\u300230 mg\/gCr\u4ee5\u4e0a\u3067\u300c\u65e9\u671f\u814e\u75c7\u300d\u3068\u5224\u5b9a\u3055\u308c\u307e\u3059\u3002<\/p>\n<p style=\"margin: 0;\"><strong>\u6cbb\u7642\uff1a<\/strong>\u53b3\u683c\u306a\u8840\u7cd6\u7ba1\u7406\u306b\u52a0\u3048\u3001\u8840\u5727\u7ba1\u7406\uff08ACE\u963b\u5bb3\u85ac\/ARB\uff09\u3001\u6700\u8fd1\u3067\u306f<strong>SGLT2\u963b\u5bb3\u85ac\u306e\u814e\u4fdd\u8b77\u52b9\u679c<\/strong>\u304c\u5927\u898f\u6a21\u81e8\u5e8a\u8a66\u9a13\u3067\u78ba\u8a8d\u3055\u308c\u3066\u3044\u307e\u3059\uff08EMPA-KIDNEY\u8a66\u9a13\u3001DAPA-CKD\u8a66\u9a13\u306a\u3069\uff09\u3002<\/p>\n<\/div>\n<p><!-- ===== 7. \u5927\u8840\u7ba1\u5408\u4f75\u75c7 ===== --><\/p>\n<h2 id=\"sec7\" style=\"color: #1a237e; border-left: 5px solid #1a237e; padding-left: 12px; margin-top: 45px;\">7. \u5927\u8840\u7ba1\u5408\u4f75\u75c7 \u2500\u2500\u300c\u3048\u30fb\u306e\u30fb\u304d\u300d\u306e\u899a\u3048\u65b9<\/h2>\n<p>\u7cd6\u5c3f\u75c5\u306f\u52d5\u8108\u786c\u5316\u3092\u5f37\u529b\u306b\u4fc3\u9032\u3057\u307e\u3059\u3002\u5927\u8840\u7ba1\u5408\u4f75\u75c7\u306f<strong>\u300c\u3048\u30fb\u306e\u30fb\u304d\u300d<\/strong>\u3068\u899a\u3048\u307e\u3059\u3002\u3053\u308c\u3089\u306f\u7cd6\u5c3f\u75c5\u3067\u306a\u304f\u3066\u3082\u8d77\u3053\u308a\u5f97\u307e\u3059\u304c\u3001\u7cd6\u5c3f\u75c5\u304c\u3042\u308b\u3068<strong>\u767a\u75c7\u30ea\u30b9\u30af\u304c2\uff5e4\u500d<\/strong>\u306b\u4e0a\u6607\u3057\u307e\u3059\u3002<\/p>\n<p><!-- \u3048\uff1a\u58ca\u75bd --><\/p>\n<h3 style=\"color: #c62828; margin-top: 25px;\">\u3048\uff1a\u58ca\u75bd\uff08Gangrene\uff09\u2500\u2500 \u7cd6\u5c3f\u75c5\u8db3\u75c5\u5909\u30fb\u4e0b\u80a2\u5207\u65ad<\/h3>\n<p>\u672b\u68a2\u52d5\u8108\u75be\u60a3\uff08PAD\uff09\u3068\u795e\u7d4c\u969c\u5bb3\u306b\u3088\u308a\u8db3\u306e\u8840\u6d41\u3068\u611f\u899a\u304c\u4f4e\u4e0b\u3057\u3001\u5c0f\u3055\u306a\u50b7\u304b\u3089\u58ca\u75bd\u306b\u9032\u5c55\u3057\u307e\u3059\u3002<strong>\u7cd6\u5c3f\u75c5\u60a3\u8005\u306e\u4e0b\u80a2\u5207\u65ad\u30ea\u30b9\u30af\u306f\u975e\u7cd6\u5c3f\u75c5\u8005\u306e15\uff5e40\u500d<\/strong>\u3068\u3055\u308c\u307e\u3059\u3002Fournier\u58ca\u75bd\u3082\u5e83\u3044\u610f\u5473\u3067\u306f\u3053\u306e\u30ab\u30c6\u30b4\u30ea\u30fc\u306b\u95a2\u9023\u3057\u307e\u3059\u3002<\/p>\n<p><!-- \u306e\uff1a\u8133\u5352\u4e2d --><\/p>\n<h3 style=\"color: #c62828; margin-top: 25px;\">\u306e\uff1a\u8133\u5352\u4e2d\uff08Stroke\uff09\u2500\u2500 \u8133\u6897\u585e\u30fb\u8133\u51fa\u8840<\/h3>\n<p>\u7cd6\u5c3f\u75c5\u60a3\u8005\u306e\u8133\u6897\u585e\u767a\u75c7\u30ea\u30b9\u30af\u306f2\uff5e4\u500d\u306b\u4e0a\u6607\u3057\u307e\u3059\u3002\u9ad8\u8840\u7cd6\u72b6\u614b\u306f\u8840\u7ba1\u5185\u76ae\u3092\u50b7\u3064\u3051\u3001\u52d5\u8108\u786c\u5316\u3092\u4fc3\u9032\u3057\u3001\u8840\u6813\u3092\u5f62\u6210\u3057\u3084\u3059\u304f\u3057\u307e\u3059\u3002\u306a\u304a\u3001<strong>\u8133\u6897\u585e\u306e\u4e00\u6b21\u4e88\u9632\u306b\u304a\u3044\u3066\u3001\u304b\u3064\u3066\u300c\u5e38\u8b58\u300d\u3068\u3055\u308c\u305f\u30a2\u30b9\u30d4\u30ea\u30f3\u5185\u670d\u306f\u73fe\u5728\u306f\u63a8\u5968\u3055\u308c\u3066\u3044\u307e\u305b\u3093<\/strong>\uff08JPPP\u8a66\u9a13\u3001ASCEND\u8a66\u9a13\u306a\u3069\uff09\u3002\u30ea\u30b9\u30af\u7ba1\u7406\u3068\u3057\u3066\u6700\u3082\u91cd\u8981\u306a\u306e\u306f\u8840\u7cd6\u30fb\u8840\u5727\u30fb\u8102\u8cea\u306e\u5305\u62ec\u7684\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3067\u3059\u3002<\/p>\n<p style=\"font-size: 0.9em; color: #666;\">&#x25b6; \u95a2\u9023\u8a18\u4e8b\uff1a<a href=\"https:\/\/www.takeuchi-iin.jp\/blog\/%e3%80%90%e8%84%b3%e6%a2%97%e5%a1%9e%e4%b8%80%e6%ac%a1%e4%ba%88%e9%98%b2%e3%80%91%e3%81%95%e3%82%89%e3%81%b0%e3%80%8c%e3%82%a2%e3%82%b9%e3%83%94%e3%83%aa%e3%83%b3%e7%a5%9e%e8%a9%b1%e3%80%8d%e2%94%80\/\" style=\"color: #1e88e5;\">\u3010\u8133\u6897\u585e\u4e00\u6b21\u4e88\u9632\u3011\u3055\u3089\u3070\u300c\u30a2\u30b9\u30d4\u30ea\u30f3\u795e\u8a71\u300d<\/a><\/p>\n<p><!-- \u304d\uff1a\u865a\u8840\u6027\u5fc3\u75be\u60a3 --><\/p>\n<h3 style=\"color: #c62828; margin-top: 25px;\">\u304d\uff1a\u865a\u8840\u6027\u5fc3\u75be\u60a3\uff08Coronary Artery Disease\uff09\u2500\u2500 \u5fc3\u7b4b\u6897\u585e\u30fb\u72ed\u5fc3\u75c7<\/h3>\n<p>\u7cd6\u5c3f\u75c5\u60a3\u8005\u306e\u5fc3\u7b4b\u6897\u585e\u30ea\u30b9\u30af\u306f2\uff5e3\u500d\u3001\u5fc3\u4e0d\u5168\u30ea\u30b9\u30af\u30822\uff5e5\u500d\u306b\u4e0a\u6607\u3057\u307e\u3059\u3002\u7279\u306b\u6ce8\u610f\u3059\u3079\u304d\u306f\u3001\u7cd6\u5c3f\u75c5\u6027\u795e\u7d4c\u969c\u5bb3\u306b\u3088\u308a<strong>\u80f8\u75db\u3092\u611f\u3058\u306b\u304f\u3044\u300c\u7121\u75db\u6027\u5fc3\u7b4b\u6897\u585e\u300d<\/strong>\u304c\u591a\u3044\u3053\u3068\u3067\u3059\u3002\u5fc3\u7b4b\u6897\u585e\u306e\u5178\u578b\u7684\u306a\u75c7\u72b6\uff08\u80f8\u3092\u7de0\u3081\u3064\u3051\u308b\u3088\u3046\u306a\u75db\u307f\uff09\u304c\u51fa\u306a\u3044\u307e\u307e\u3001\u7a81\u7136\u5fc3\u505c\u6b62\u306b\u81f3\u308b\u30b1\u30fc\u30b9\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n<p><!-- ===== 8. \u611f\u67d3\u75c7\u30ea\u30b9\u30af ===== --><\/p>\n<h2 id=\"sec8\" style=\"color: #1a237e; border-left: 5px solid #1a237e; padding-left: 12px; margin-top: 45px;\">8. \u611f\u67d3\u75c7\u30ea\u30b9\u30af\u306e\u5897\u5927 \u2500\u2500 Fournier\u58ca\u75bd\u3082\u305d\u306e\u4e00\u3064<\/h2>\n<p>\u7cd6\u5c3f\u75c5\u306f\u514d\u75ab\u6a5f\u80fd\u3092\u591a\u9762\u7684\u306b\u4f4e\u4e0b\u3055\u305b\u308b\u305f\u3081\u3001\u3055\u307e\u3056\u307e\u306a\u611f\u67d3\u75c7\u306b\u304b\u304b\u308a\u3084\u3059\u304f\u3001\u91cd\u75c7\u5316\u3082\u3057\u3084\u3059\u304f\u306a\u308a\u307e\u3059\u3002<strong>Fournier\u58ca\u75bd\u3082\u3053\u306e\u300c\u7cd6\u5c3f\u75c5\u95a2\u9023\u611f\u67d3\u75c7\u300d\u306e\u4e00\u3064<\/strong>\u3068\u3057\u3066\u4f4d\u7f6e\u3065\u3051\u3089\u308c\u307e\u3059\u3002<\/p>\n<p><!-- \u30dd\u30a4\u30f3\u30c8\u30dc\u30c3\u30af\u30b9\uff08\u9752\/\u6c34\u8272\uff09 --><\/p>\n<div style=\"background: #e3f2fd; border: 2px solid #1e88e5; border-radius: 10px; padding: 22px; margin: 20px 0;\">\n<p style=\"font-weight: bold; color: #1565c0; margin: 0 0 12px 0; font-size: 1.05em;\">\u7cd6\u5c3f\u75c5\u3067\u6ce8\u610f\u3059\u3079\u304d\u611f\u67d3\u75c7<\/p>\n<table style=\"width: 100%; border-collapse: collapse; font-size: 0.95em;\">\n<tr style=\"background: #bbdefb;\">\n<th style=\"padding: 10px; text-align: left;\">\u611f\u67d3\u90e8\u4f4d<\/th>\n<th style=\"padding: 10px; text-align: left;\">\u4ee3\u8868\u7684\u306a\u75be\u60a3<\/th>\n<\/tr>\n<tr style=\"border-bottom: 1px solid #e0e0e0;\">\n<td style=\"padding: 8px 10px;\">\u76ae\u819a\u30fb\u8edf\u90e8\u7d44\u7e54<\/td>\n<td style=\"padding: 8px 10px;\"><strong>Fournier\u58ca\u75bd<\/strong>\u3001\u8702\u7aa9\u7e54\u708e\u3001\u7cd6\u5c3f\u75c5\u8db3\u611f\u67d3\u3001\u58ca\u6b7b\u6027\u7b4b\u819c\u708e<\/td>\n<\/tr>\n<tr style=\"border-bottom: 1px solid #e0e0e0;\">\n<td style=\"padding: 8px 10px;\">\u5c3f\u8def<\/td>\n<td style=\"padding: 8px 10px;\">\u8180\u80f1\u708e\u3001\u814e\u76c2\u814e\u708e\u3001\u6c17\u816b\u6027\u814e\u76c2\u814e\u708e<\/td>\n<\/tr>\n<tr style=\"border-bottom: 1px solid #e0e0e0;\">\n<td style=\"padding: 8px 10px;\">\u547c\u5438\u5668<\/td>\n<td style=\"padding: 8px 10px;\">\u80ba\u708e\uff08\u80ba\u708e\u7403\u83cc\u6027\u542b\u3080\uff09\u3001\u80ba\u7d50\u6838\u3001COVID-19\u91cd\u75c7\u5316<\/td>\n<\/tr>\n<tr style=\"border-bottom: 1px solid #e0e0e0;\">\n<td style=\"padding: 8px 10px;\">\u771f\u83cc<\/td>\n<td style=\"padding: 8px 10px;\">\u30ab\u30f3\u30b8\u30c0\u75c7\uff08\u6027\u5668\u30fb\u53e3\u8154\uff09\u3001\u30e0\u30b3\u30fc\u30eb\u75c7<\/td>\n<\/tr>\n<tr style=\"border-bottom: 1px solid #e0e0e0;\">\n<td style=\"padding: 8px 10px;\">\u53e3\u8154<\/td>\n<td style=\"padding: 8px 10px;\">\u6b6f\u5468\u75c5\uff08\u7cd6\u5c3f\u75c5\u306e\u300c\u7b2c6\u306e\u5408\u4f75\u75c7\u300d\u3068\u3082\uff09<\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 8px 10px;\">\u305d\u306e\u4ed6<\/td>\n<td style=\"padding: 8px 10px;\">\u5e2f\u72b6\u75b1\u75b9\u3001\u60aa\u6027\u5916\u8033\u9053\u708e<\/td>\n<\/tr>\n<\/table>\n<\/div>\n<p>\u7cd6\u5c3f\u75c5\u60a3\u8005\u306b\u306f<strong>\u80ba\u708e\u7403\u83cc\u30ef\u30af\u30c1\u30f3\u3001\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u30ef\u30af\u30c1\u30f3\u3001\u5e2f\u72b6\u75b1\u75b9\u30ef\u30af\u30c1\u30f3<\/strong>\u306a\u3069\u306e\u7a4d\u6975\u7684\u306a\u4e88\u9632\u63a5\u7a2e\u304c\u63a8\u5968\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u5f53\u9662\u3067\u306f\u3053\u308c\u3089\u306e\u30ef\u30af\u30c1\u30f3\u3059\u3079\u3066\u306b\u5bfe\u5fdc\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n<p><!-- ===== 9. \u8840\u7cd6\u7ba1\u7406\u76ee\u6a19 ===== --><\/p>\n<h2 id=\"sec9\" style=\"color: #1a237e; border-left: 5px solid #1a237e; padding-left: 12px; margin-top: 45px;\">9. \u7cd6\u5c3f\u75c5\u5408\u4f75\u75c7\u3092\u9632\u3050\u305f\u3081\u306e\u8840\u7cd6\u7ba1\u7406\u76ee\u6a19<\/h2>\n<p>\u7cd6\u5c3f\u75c5\u8a3a\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f32024\uff08\u65e5\u672c\u7cd6\u5c3f\u75c5\u5b66\u4f1a\uff09\u304a\u3088\u3073ADA Standards of Care 2025\u306b\u57fa\u3065\u304f\u73fe\u5728\u306e\u8840\u7cd6\u7ba1\u7406\u76ee\u6a19\u3067\u3059\u3002<\/p>\n<p><!-- \u91cd\u8981\u30dc\u30c3\u30af\u30b9\uff08\u8d64\/\u30d4\u30f3\u30af\uff09 --><\/p>\n<div style=\"background: #fce4ec; border: 2px solid #e91e63; border-radius: 10px; padding: 22px; margin: 20px 0;\">\n<p style=\"font-weight: bold; color: #ad1457; margin: 0 0 12px 0; font-size: 1.05em;\">HbA1c\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u76ee\u6a19\u5024<\/p>\n<table style=\"width: 100%; border-collapse: collapse; font-size: 0.95em;\">\n<tr style=\"background: #f8bbd0;\">\n<th style=\"padding: 10px; text-align: left;\">\u76ee\u6a19\u30ab\u30c6\u30b4\u30ea\u30fc<\/th>\n<th style=\"padding: 10px; text-align: center;\">HbA1c<\/th>\n<th style=\"padding: 10px; text-align: left;\">\u5bfe\u8c61<\/th>\n<\/tr>\n<tr style=\"border-bottom: 1px solid #e0e0e0;\">\n<td style=\"padding: 10px;\">\u8840\u7cd6\u6b63\u5e38\u5316\u3092\u76ee\u6307\u3059<\/td>\n<td style=\"padding: 10px; text-align: center; font-weight: bold; color: #2e7d32;\">6.0%\u672a\u6e80<\/td>\n<td style=\"padding: 10px;\">\u98df\u4e8b\u30fb\u904b\u52d5\u7642\u6cd5\u306e\u307f\u3067\u9054\u6210\u53ef\u80fd\u306a\u5834\u5408<\/td>\n<\/tr>\n<tr style=\"border-bottom: 1px solid #e0e0e0;\">\n<td style=\"padding: 10px;\">\u5408\u4f75\u75c7\u4e88\u9632\u306e\u305f\u3081\u306e\u76ee\u6a19<\/td>\n<td style=\"padding: 10px; text-align: center; font-weight: bold; color: #1565c0;\">7.0%\u672a\u6e80<\/td>\n<td style=\"padding: 10px;\">\u591a\u304f\u306e\u6210\u4eba\u7cd6\u5c3f\u75c5\u60a3\u8005<\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 10px;\">\u6cbb\u7642\u5f37\u5316\u304c\u56f0\u96e3\u306a\u5834\u5408<\/td>\n<td style=\"padding: 10px; text-align: center; font-weight: bold; color: #e65100;\">8.0%\u672a\u6e80<\/td>\n<td style=\"padding: 10px;\">\u9ad8\u9f62\u8005\u30fb\u4f4e\u8840\u7cd6\u30ea\u30b9\u30af\u306e\u9ad8\u3044\u60a3\u8005\u306a\u3069<\/td>\n<\/tr>\n<\/table>\n<p style=\"margin: 10px 0 0 0; font-size: 0.9em; color: #888;\">\u203b\u9ad8\u9f62\u8005\u306f\u8a8d\u77e5\u6a5f\u80fd\u30fbADL\u30fb\u4f75\u5b58\u75be\u60a3\u3092\u8003\u616e\u3057\u3066\u500b\u5225\u306b\u8a2d\u5b9a\u3057\u307e\u3059\uff08\u7cd6\u5c3f\u75c5\u6cbb\u7642\u30ac\u30a4\u30c92024\uff09<\/p>\n<\/div>\n<p><!-- \u30a8\u30d3\u30c7\u30f3\u30b9\u30dc\u30c3\u30af\u30b9\uff08\u7dd1\uff09 --><\/p>\n<div style=\"background: #e8f5e9; border: 2px solid #43a047; border-radius: 10px; padding: 22px; margin: 20px 0;\">\n<p style=\"font-weight: bold; color: #2e7d32; margin: 0 0 10px 0;\">\u5408\u4f75\u75c7\u4e88\u9632\u306e\u305f\u3081\u306e\u5305\u62ec\u7ba1\u7406\uff08ABC\u7ba1\u7406\uff09<\/p>\n<p style=\"margin: 0 0 8px 0;\"><strong>A\uff08A1c\uff09\uff1a<\/strong>HbA1c 7.0%\u672a\u6e80<\/p>\n<p style=\"margin: 0 0 8px 0;\"><strong>B\uff08Blood Pressure\uff09\uff1a<\/strong>\u8840\u5727 130\/80 mmHg\u672a\u6e80\uff08\u7cd6\u5c3f\u75c5\u5408\u4f75\u6642\uff09<\/p>\n<p style=\"margin: 0 0 8px 0;\"><strong>C\uff08Cholesterol\uff09\uff1a<\/strong>LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb 120 mg\/dL\u672a\u6e80\uff08\u51a0\u52d5\u8108\u75be\u60a3\u65e2\u5f80\u3042\u308c\u3070100\u672a\u6e80\uff09<\/p>\n<p style=\"margin: 0;\"><strong>\u305d\u306e\u4ed6\uff1a<\/strong>\u7981\u7159\u3001\u4f53\u91cd\u7ba1\u7406\u3001\u5b9a\u671f\u7684\u306a\u5408\u4f75\u75c7\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0<\/p>\n<\/div>\n<p><!-- ===== 10. \u5f53\u9662\u3067\u3067\u304d\u308b\u3053\u3068 ===== --><\/p>\n<h2 id=\"sec10\" style=\"color: #1a237e; border-left: 5px solid #1a237e; padding-left: 12px; margin-top: 45px;\">10. \u5f53\u9662\u3067\u3067\u304d\u308b\u3053\u3068 \u2500\u2500 \u5305\u62ec\u7684\u306a\u7cd6\u5c3f\u75c5\u30b5\u30dd\u30fc\u30c8<\/h2>\n<p>\u7af9\u5185\u5185\u79d1\u5c0f\u5150\u79d1\u533b\u9662\u306f<strong>\u7cd6\u5c3f\u75c5\u5185\u79d1\u30fb\u4ee3\u8b1d\u5185\u79d1<\/strong>\u3092\u8a3a\u7642\u79d1\u76ee\u3068\u3057\u3066\u63b2\u3052\u3001\u7cd6\u5c3f\u75c5\u306e\u8a3a\u65ad\u304b\u3089\u6cbb\u7642\u3001\u5408\u4f75\u75c7\u7ba1\u7406\u307e\u3067\u4e00\u8cab\u3057\u305f\u30b5\u30dd\u30fc\u30c8\u3092\u63d0\u4f9b\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n<p><!-- \u30dd\u30a4\u30f3\u30c8\u30dc\u30c3\u30af\u30b9\uff08\u9752\uff09 --><\/p>\n<div style=\"background: #e3f2fd; border: 2px solid #1e88e5; border-radius: 10px; padding: 22px; margin: 20px 0;\">\n<p style=\"font-weight: bold; color: #1565c0; margin: 0 0 12px 0; font-size: 1.05em;\">\u5f53\u9662\u306e\u7cd6\u5c3f\u75c5\u8a3a\u7642\u30e1\u30cb\u30e5\u30fc<\/p>\n<p style=\"margin: 0 0 10px 0;\"><strong style=\"color: #1565c0;\">\u691c\u67fb\u30fb\u8a3a\u65ad<\/strong><br \/>\n\u8840\u6db2\u691c\u67fb\uff08HbA1c\u3001\u7a7a\u8179\u6642\u8840\u7cd6\u3001GA\u3001\u8102\u8cea\u30d1\u30cd\u30eb\u3001\u814e\u6a5f\u80fd\uff09\u3001\u5c3f\u691c\u67fb\uff08\u5c3f\u30a2\u30eb\u30d6\u30df\u30f3\u3001\u5c3f\u7cd6\uff09\u3001\u4f53\u5185\u7cd6\u5316\u5ea6\u691c\u67fb\uff08AGEs\u6e2c\u5b9a\uff09\u3001\u52d5\u8108\u786c\u5316\u691c\u67fb\uff08CAVI\/ABI\uff09<\/p>\n<p style=\"margin: 0 0 10px 0;\"><strong style=\"color: #1565c0;\">\u6cbb\u7642\u30fb\u7ba1\u7406<\/strong><br \/>\n\u98df\u4e8b\u7642\u6cd5\u30fb\u904b\u52d5\u7642\u6cd5\u306e\u6307\u5c0e\u3001\u7d4c\u53e3\u8840\u7cd6\u964d\u4e0b\u85ac\uff08\u30e1\u30c8\u30db\u30eb\u30df\u30f3\u3001SGLT2\u963b\u5bb3\u85ac\u3001DPP-4\u963b\u5bb3\u85ac\u3001GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u306a\u3069\uff09\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u7642\u6cd5\u3001\u751f\u6d3b\u7fd2\u6163\u75c5\u306e\u5305\u62ec\u7ba1\u7406\uff08\u8840\u5727\u30fb\u8102\u8cea\u30fb\u4f53\u91cd\uff09<\/p>\n<p style=\"margin: 0 0 10px 0;\"><strong style=\"color: #1565c0;\">\u5408\u4f75\u75c7\u30c1\u30a7\u30c3\u30af<\/strong><br \/>\n\u5b9a\u671f\u7684\u306a\u5c3f\u4e2d\u30a2\u30eb\u30d6\u30df\u30f3\u6e2c\u5b9a\uff08\u814e\u75c7\uff09\u3001\u773c\u79d1\u53d7\u8a3a\u306e\u63a8\u5968\u3068\u9023\u643a\uff08\u7db2\u819c\u75c7\uff09\u3001\u8db3\u306e\u89b3\u5bdf\u6307\u5c0e\uff08\u8db3\u75c5\u5909\u4e88\u9632\uff09\u3001\u5fc3\u96fb\u56f3\u691c\u67fb\u3001\u9838\u52d5\u8108\u30a8\u30b3\u30fc<\/p>\n<p style=\"margin: 0;\"><strong style=\"color: #1565c0;\">\u6804\u990a\u6307\u5c0e<\/strong><br \/>\n\u7ba1\u7406\u6804\u990a\u58eb\u306b\u3088\u308b\u500b\u5225\u306e\u98df\u4e8b\u30ab\u30a6\u30f3\u30bb\u30ea\u30f3\u30b0\uff08\u8981\u4e88\u7d04\uff09<\/p>\n<\/div>\n<p>\u9662\u9577\u30fb\u4e94\u85e4\u826f\u5c06\u306f\u8457\u66f8<strong>\u300e<a href=\"https:\/\/amzn.asia\/d\/05aU1Ae8\" target=\"_blank\" rel=\"noopener\" style=\"color: #1e88e5;\">\u8840\u6db2\u3068\u4f53\u306e\u300c\u3042\u3076\u3089\u300d\u3092\u843d\u3068\u3059\u30b9\u30fc\u30d7<\/a>\u300f<\/strong>\uff08\u30a2\u30b9\u30b3\u30e0, 2024\u5e74\uff09\u3067Amazon\u30d9\u30b9\u30c8\u30bb\u30e9\u30fc\u3092\u7372\u5f97\u3059\u308b\u306a\u3069\u3001\u98df\u4e8b\u7642\u6cd5\u3092\u91cd\u8996\u3057\u305f\u7cd6\u5c3f\u75c5\u8a3a\u7642\u306b\u529b\u3092\u5165\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<p><!-- ===== 11. FAQ ===== --><\/p>\n<h2 id=\"sec11\" style=\"color: #1a237e; border-left: 5px solid #1a237e; padding-left: 12px; margin-top: 45px;\">11. FAQ\uff08\u3088\u304f\u3042\u308b\u3054\u8cea\u554f\uff09<\/h2>\n<p><!-- Q1 --><\/p>\n<div style=\"margin-bottom: 20px;\">\n<p style=\"background: #1a237e; color: white; padding: 12px 15px; border-radius: 8px 8px 0 0; margin: 0; font-weight: bold;\">Q1. Fournier\u58ca\u75bd\u306f\u3069\u306e\u3088\u3046\u306a\u4eba\u304c\u306a\u308a\u3084\u3059\u3044\u3067\u3059\u304b\uff1f<\/p>\n<div style=\"background: #f5f5f5; padding: 15px; border-radius: 0 0 8px 8px; border: 1px solid #e0e0e0; border-top: none;\">\n<p style=\"margin: 0;\">\u6700\u5927\u306e\u30ea\u30b9\u30af\u56e0\u5b50\u306f<strong>\u7cd6\u5c3f\u75c5<\/strong>\u3067\u3001\u60a3\u8005\u306e40\uff5e62%\u304c\u7cd6\u5c3f\u75c5\u3092\u6709\u3057\u3066\u3044\u307e\u3059\u3002\u305d\u306e\u4ed6\u3001\u514d\u75ab\u4e0d\u5168\uff08HIV\u611f\u67d3\u75c7\u7b49\uff09\u3001\u6162\u6027\u30a2\u30eb\u30b3\u30fc\u30eb\u4f9d\u5b58\u75c7\u3001\u814e\u4e0d\u5168\u3001\u80a5\u6e80\u3001\u9ad8\u9f62\u306a\u3069\u3082\u30ea\u30b9\u30af\u56e0\u5b50\u3067\u3059\u300250\uff5e70\u4ee3\u7537\u6027\u306b\u591a\u3044\u3067\u3059\u304c\u300133\u6b73\u3067\u3042\u3063\u305f\u82e5\u6238\u685c\u3055\u3093\u306e\u3088\u3046\u306b\u82e5\u5e74\u4f8b\u3082\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<\/div>\n<\/div>\n<p><!-- Q2 --><\/p>\n<div style=\"margin-bottom: 20px;\">\n<p style=\"background: #1a237e; color: white; padding: 12px 15px; border-radius: 8px 8px 0 0; margin: 0; font-weight: bold;\">Q2. SGLT2\u963b\u5bb3\u85ac\u3092\u670d\u7528\u4e2d\u3067\u3059\u304c\u3001\u3059\u3050\u306b\u3084\u3081\u305f\u307b\u3046\u304c\u3044\u3044\u3067\u3059\u304b\uff1f<\/p>\n<div style=\"background: #f5f5f5; padding: 15px; border-radius: 0 0 8px 8px; border: 1px solid #e0e0e0; border-top: none;\">\n<p style=\"margin: 0;\"><strong>\u81ea\u5df1\u5224\u65ad\u3067\u306e\u4e2d\u65ad\u306f\u304a\u52e7\u3081\u3057\u307e\u305b\u3093\u3002<\/strong>SGLT2\u963b\u5bb3\u85ac\u306eFournier\u58ca\u75bd\u30ea\u30b9\u30af\u306f\u6975\u3081\u3066\u4f4e\u983b\u5ea6\u3067\u3042\u308a\u3001\u4e00\u65b9\u3067\u5fc3\u4e0d\u5168\u4e88\u9632\u30fb\u814e\u4fdd\u8b77\u30fb\u8840\u7cd6\u6539\u5584\u3068\u3044\u3046\u5927\u304d\u306a\u30e1\u30ea\u30c3\u30c8\u304c\u3042\u308a\u307e\u3059\u3002\u5916\u9670\u90e8\u306e\u7570\u5e38\uff08\u767a\u8d64\u30fb\u816b\u8139\u30fb\u75bc\u75db\uff09\u3084\u767a\u71b1\u3092\u611f\u3058\u305f\u3089\u3001\u3059\u3050\u306b\u4e3b\u6cbb\u533b\u306b\u76f8\u8ac7\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n<\/div>\n<\/div>\n<p><!-- Q3 --><\/p>\n<div style=\"margin-bottom: 20px;\">\n<p style=\"background: #1a237e; color: white; padding: 12px 15px; border-radius: 8px 8px 0 0; margin: 0; font-weight: bold;\">Q3. \u7cd6\u5c3f\u75c5\u3068\u8a00\u308f\u308c\u307e\u3057\u305f\u304c\u75c7\u72b6\u304c\u3042\u308a\u307e\u305b\u3093\u3002\u6cbb\u7642\u306f\u5fc5\u8981\u3067\u3059\u304b\uff1f<\/p>\n<div style=\"background: #f5f5f5; padding: 15px; border-radius: 0 0 8px 8px; border: 1px solid #e0e0e0; border-top: none;\">\n<p style=\"margin: 0;\"><strong>\u306f\u3044\u3001\u5fc5\u305a\u6cbb\u7642\u3092\u958b\u59cb\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/strong>\u7cd6\u5c3f\u75c5\u306f\u300c\u75c7\u72b6\u304c\u306a\u3044\u3053\u3068\u300d\u304c\u6700\u5927\u306e\u843d\u3068\u3057\u7a74\u3067\u3059\u3002\u9ad8\u8840\u7cd6\u72b6\u614b\u304c\u7d9a\u304f\u3068\u3001\u77e5\u3089\u306a\u3044\u3046\u3061\u306b\u8840\u7ba1\u3068\u795e\u7d4c\u304c\u50b7\u3064\u304d\u3001\u6570\u5e74\u5f8c\u306b\u7db2\u819c\u75c7\u30fb\u814e\u75c7\u30fb\u795e\u7d4c\u969c\u5bb3\u30fb\u5fc3\u7b4b\u6897\u585e\u306a\u3069\u306e\u5408\u4f75\u75c7\u304c\u51fa\u73fe\u3057\u307e\u3059\u3002\u65e9\u671f\u306b\u6cbb\u7642\u3092\u958b\u59cb\u3059\u308b\u307b\u3069\u5408\u4f75\u75c7\u30ea\u30b9\u30af\u3092\u5927\u5e45\u306b\u4f4e\u6e1b\u3067\u304d\u307e\u3059\uff08\u30ec\u30ac\u30b7\u30fc\u52b9\u679c\uff09\u3002<\/p>\n<\/div>\n<\/div>\n<p><!-- Q4 --><\/p>\n<div style=\"margin-bottom: 20px;\">\n<p style=\"background: #1a237e; color: white; padding: 12px 15px; border-radius: 8px 8px 0 0; margin: 0; font-weight: bold;\">Q4. \u7cd6\u5c3f\u75c5\u306e\u5408\u4f75\u75c7\u30c1\u30a7\u30c3\u30af\u306f\u3069\u306e\u304f\u3089\u3044\u306e\u983b\u5ea6\u3067\u884c\u3046\u3079\u304d\u3067\u3059\u304b\uff1f<\/p>\n<div style=\"background: #f5f5f5; padding: 15px; border-radius: 0 0 8px 8px; border: 1px solid #e0e0e0; border-top: none;\">\n<p style=\"margin: 0;\">\u7cd6\u5c3f\u75c5\u8a3a\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f32024\u306b\u57fa\u3065\u304f\u63a8\u5968\u983b\u5ea6\u306f\u3001<strong>HbA1c\u30fb\u8840\u7cd6\u691c\u67fb\uff1a\u6bce\u56de\u306e\u8a3a\u5bdf\u6642\uff081\uff5e3\u304b\u6708\u3054\u3068\uff09<\/strong>\u3001<strong>\u5c3f\u4e2d\u30a2\u30eb\u30d6\u30df\u30f3\u691c\u67fb\uff1a\u5e74\u306b\u6570\u56de<\/strong>\u3001<strong>\u773c\u5e95\u691c\u67fb\uff08\u773c\u79d1\uff09\uff1a\u534a\u5e74\u306b1\u56de<\/strong>\u3001<strong>\u52d5\u8108\u786c\u5316\u691c\u67fb\uff1a1\uff5e2\u5e74\u306b1\u56de<\/strong>\u3001<strong>\u5fc3\u96fb\u56f3\uff1a\u5e741\u56de\u7a0b\u5ea6<\/strong>\u3001<strong>\u8db3\u306e\u8a3a\u5bdf\uff1a\u6bce\u56de\u306e\u53d7\u8a3a\u6642<\/strong>\u3067\u3059\u3002\u5f53\u9662\u3067\u306f\u3053\u308c\u3089\u3092\u5305\u62ec\u7684\u306b\u30d5\u30a9\u30ed\u30fc\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n<\/div>\n<\/div>\n<p><!-- Q5 --><\/p>\n<div style=\"margin-bottom: 20px;\">\n<p style=\"background: #1a237e; color: white; padding: 12px 15px; border-radius: 8px 8px 0 0; margin: 0; font-weight: bold;\">Q5. \u7cd6\u5c3f\u75c5\u304c\u3042\u308b\u3068\u611f\u67d3\u75c7\u306b\u304b\u304b\u308a\u3084\u3059\u3044\u3068\u805e\u304d\u307e\u3057\u305f\u3002\u4e88\u9632\u63a5\u7a2e\u306f\u53d7\u3051\u305f\u307b\u3046\u304c\u3044\u3044\u3067\u3059\u304b\uff1f<\/p>\n<div style=\"background: #f5f5f5; padding: 15px; border-radius: 0 0 8px 8px; border: 1px solid #e0e0e0; border-top: none;\">\n<p style=\"margin: 0;\"><strong>\u306f\u3044\u3001\u7a4d\u6975\u7684\u306b\u63a5\u7a2e\u3092\u304a\u52e7\u3081\u3057\u307e\u3059\u3002<\/strong>\u7cd6\u5c3f\u75c5\u306f\u514d\u75ab\u6a5f\u80fd\u3092\u4f4e\u4e0b\u3055\u305b\u308b\u305f\u3081\u3001\u80ba\u708e\u7403\u83cc\u30ef\u30af\u30c1\u30f3\u3001\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u30ef\u30af\u30c1\u30f3\u3001\u5e2f\u72b6\u75b1\u75b9\u30ef\u30af\u30c1\u30f3\uff08\u30b7\u30f3\u30b0\u30ea\u30c3\u30af\u30b9\uff09\u3001\u65b0\u578b\u30b3\u30ed\u30ca\u30ef\u30af\u30c1\u30f3\u306a\u3069\u306e\u63a5\u7a2e\u304c\u63a8\u5968\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u5f53\u9662\u3067\u306f\u3053\u308c\u3089\u3059\u3079\u3066\u306b\u5bfe\u5fdc\u3057\u3066\u304a\u308a\u307e\u3059\u3002<\/p>\n<\/div>\n<\/div>\n<p><!-- Q6 --><\/p>\n<div style=\"margin-bottom: 20px;\">\n<p style=\"background: #1a237e; color: white; padding: 12px 15px; border-radius: 8px 8px 0 0; margin: 0; font-weight: bold;\">Q6. HbA1c\u304c7%\u53f0\u3067\u5b89\u5b9a\u3057\u3066\u3044\u307e\u3059\u304c\u3001\u5408\u4f75\u75c7\u306e\u30ea\u30b9\u30af\u306f\u3042\u308a\u307e\u3059\u304b\uff1f<\/p>\n<div style=\"background: #f5f5f5; padding: 15px; border-radius: 0 0 8px 8px; border: 1px solid #e0e0e0; border-top: none;\">\n<p style=\"margin: 0;\">HbA1c 7.0%\u672a\u6e80\u304c\u5408\u4f75\u75c7\u4e88\u9632\u306e\u76ee\u6a19\u3067\u3059\u306e\u3067\u30017%\u53f0\u306f\u3082\u3046\u5c11\u3057\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3092\u6539\u5584\u3057\u305f\u3044\u7bc4\u56f2\u3067\u3059\u3002\u305f\u3060\u3057\u3001HbA1c\u3060\u3051\u3067\u306a\u304f<strong>\u8840\u5727\u30fb\u8102\u8cea\u30fb\u4f53\u91cd\u30fb\u7981\u7159\u306a\u3069\u3092\u542b\u3081\u305f\u5305\u62ec\u7684\u7ba1\u7406<\/strong>\u304c\u5408\u4f75\u75c7\u4e88\u9632\u306b\u306f\u91cd\u8981\u3067\u3059\u3002\u307e\u305f\u3001\u8840\u7cd6\u5909\u52d5\uff08\u98df\u5f8c\u9ad8\u8840\u7cd6\u3084\u4f4e\u8840\u7cd6\u306e\u7e70\u308a\u8fd4\u3057\uff09\u3082\u8840\u7ba1\u969c\u5bb3\u3092\u4fc3\u9032\u3059\u308b\u305f\u3081\u3001HbA1c\u306e\u6570\u5024\u3060\u3051\u306b\u3068\u3089\u308f\u308c\u306a\u3044\u7ba1\u7406\u304c\u6c42\u3081\u3089\u308c\u307e\u3059\u3002<\/p>\n<\/div>\n<\/div>\n<p><!-- Q7 --><\/p>\n<div style=\"margin-bottom: 20px;\">\n<p style=\"background: #1a237e; color: white; padding: 12px 15px; border-radius: 8px 8px 0 0; margin: 0; font-weight: bold;\">Q7. \u7cd6\u5c3f\u75c5\u306e\u6cbb\u7642\u306f\u4e00\u751f\u7d9a\u3051\u306a\u3051\u308c\u3070\u306a\u308a\u307e\u305b\u3093\u304b\uff1f<\/p>\n<div style=\"background: #f5f5f5; padding: 15px; border-radius: 0 0 8px 8px; border: 1px solid #e0e0e0; border-top: none;\">\n<p style=\"margin: 0;\">2\u578b\u7cd6\u5c3f\u75c5\u306f\u751f\u6d3b\u7fd2\u6163\u306e\u6539\u5584\u3084\u4f53\u91cd\u6e1b\u5c11\u306b\u3088\u308a\u8840\u7cd6\u5024\u304c\u6b63\u5e38\u7bc4\u56f2\u306b\u623b\u308b\uff08\u5bdb\u89e3\u3059\u308b\uff09\u30b1\u30fc\u30b9\u3082\u3042\u308a\u307e\u3059\u3002\u7279\u306b\u8a3a\u65ad\u65e9\u671f\u3067\u80a5\u6e80\u3092\u4f34\u3046\u5834\u5408\u306f\u3001\u9069\u5207\u306a\u98df\u4e8b\u30fb\u904b\u52d5\u7642\u6cd5\u3067\u85ac\u3092\u6e1b\u91cf\u30fb\u4e2d\u6b62\u3067\u304d\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u305f\u3060\u3057\u3001\u7cd6\u5c3f\u75c5\u306b\u306a\u308a\u3084\u3059\u3044\u4f53\u8cea\u81ea\u4f53\u306f\u5909\u308f\u3089\u306a\u3044\u305f\u3081\u3001<strong>\u5b9a\u671f\u7684\u306a\u30d5\u30a9\u30ed\u30fc\u30a2\u30c3\u30d7\u306f\u7d99\u7d9a\u304c\u5fc5\u8981<\/strong>\u3067\u3059\u3002\u5f53\u9662\u3067\u306f\u300c\u3067\u304d\u308b\u3060\u3051\u85ac\u306b\u983c\u3089\u306a\u3044\u6cbb\u7642\u300d\u3092\u76ee\u6307\u3057\u3064\u3064\u3001\u5fc5\u8981\u306b\u5fdc\u3058\u3066\u9069\u5207\u306a\u85ac\u7269\u7642\u6cd5\u3092\u63d0\u6848\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n<\/div>\n<\/div>\n<p><!-- ===== \u53c2\u8003\u6587\u732e ===== --><\/p>\n<h2 id=\"ref\" style=\"color: #1a237e; border-left: 5px solid #1a237e; padding-left: 12px; margin-top: 45px;\">\u53c2\u8003\u6587\u732e<\/h2>\n<div style=\"font-size: 0.9em; color: #555; line-height: 1.8;\">\n<ol>\n<li>Shet P, et al. Risk Factors for Mortality Among Patients With Fournier Gangrene: A Systematic Review. <em>Surg Infect.<\/em> 2024;25(5):311-326. PMID: <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38625013\" style=\"color: #1e88e5;\" target=\"_blank\">38625013<\/a><\/li>\n<li>El-Qushayri AE, et al. Fournier&#8217;s gangrene mortality: A 17-year systematic review and meta-analysis. <em>Int J Infect Dis.<\/em> 2020;92:218-225. PMID: <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31962181\" style=\"color: #1e88e5;\" target=\"_blank\">31962181<\/a><\/li>\n<li>Eke N. Fournier&#8217;s gangrene: a review of 1726 cases. <em>Br J Surg.<\/em> 2000;87(6):718-728. PMID: <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/10848848\" style=\"color: #1e88e5;\" target=\"_blank\">10848848<\/a><\/li>\n<li>Lewis GD, et al. Fournier&#8217;s Gangrene Diagnosis and Treatment: A Systematic Review. <em>Cureus.<\/em> 2021;13(10):e18948. PMID: <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34815897\" style=\"color: #1e88e5;\" target=\"_blank\">34815897<\/a><\/li>\n<li>Holt RIG, et al. Diabetes and infection: mechanisms and management. <em>Diabetologia.<\/em> 2024;67(7):1168-1180. PMID: <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38374451\" style=\"color: #1e88e5;\" target=\"_blank\">38374451<\/a><\/li>\n<li>\u4eca\u77f3\u5948\u7dd2, \u4ed6. SGLT2\u963b\u5bb3\u85ac\uff08\u30c0\u30d1\u30b0\u30ea\u30d5\u30ed\u30b8\u30f3\uff09\u3092\u670d\u7528\u4e2d\u306b\u30d5\u30eb\u30cb\u30a8\u58ca\u75bd\u3092\u767a\u75c7\u3057\u305f\u9ad8\u9f622\u578b\u7cd6\u5c3f\u75c5\u306e1\u4f8b. <em>\u7cd6\u5c3f\u75c5.<\/em> 2019;62(7):389-396.<\/li>\n<li>FDA Drug Safety Communication: FDA warns about rare occurrences of a serious infection of the genital area with SGLT2 inhibitors for diabetes. August 2018.<\/li>\n<li>\u65e5\u672c\u7cd6\u5c3f\u75c5\u5b66\u4f1a. \u7cd6\u5c3f\u75c5\u8a3a\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f32024. \u5357\u6c5f\u5802, 2024.<\/li>\n<li>\u65e5\u672c\u7cd6\u5c3f\u75c5\u5b66\u4f1a. \u7cd6\u5c3f\u75c5\u6cbb\u7642\u30ac\u30a4\u30c92024. \u6587\u5149\u5802, 2024.<\/li>\n<li>\u65e5\u672c\u7cd6\u5c3f\u75c5\u30fb\u751f\u6d3b\u7fd2\u6163\u75c5\u30d2\u30e5\u30fc\u30de\u30f3\u30c7\u30fc\u30bf\u5b66\u4f1a. \u7cd6\u5c3f\u75c5\u6a19\u6e96\u8a3a\u7642\u30de\u30cb\u30e5\u30a2\u30eb2025\uff08\u7b2c21\u7248\uff09.<\/li>\n<li>American Diabetes Association. Standards of Care in Diabetes \u2500 2025. <em>Diabetes Care.<\/em> 2025;48(Suppl.1):S1-S352.<\/li>\n<li>\u76f8\u64b2\u5354\u4f1a \u5065\u5eb7\u8abf\u67fb\u5831\u544a 2018\u5e74.<\/li>\n<\/ol>\n<\/div>\n<p><!-- ===== \u9662\u9577\u7f72\u540d ===== --><\/p>\n<p style=\"text-align: right; margin-top: 40px; color: #555; font-size: 0.95em;\">\n\u7af9\u5185\u5185\u79d1\u5c0f\u5150\u79d1\u533b\u9662 \u9662\u9577<br \/>\n<strong style=\"font-size: 1.1em; color: #333;\">\u4e94\u85e4 \u826f\u5c06<\/strong>\n<\/p>\n<p><!-- ========================================== --><br \/>\n<!-- \u30af\u30ea\u30cb\u30c3\u30af\u7d39\u4ecb\u30bb\u30af\u30b7\u30e7\u30f3\uff08\u7af9\u5185\u5185\u79d1\u5c0f\u5150\u79d1\u533b\u9662\uff09 --><br \/>\n<!-- ========================================== --><\/p>\n<div style=\"margin-top: 50px; padding-top: 30px; border-top: 3px solid #e2e8f0;\">\n<p><!-- \u30e1\u30a4\u30f3\u30af\u30ea\u30cb\u30c3\u30af\u7d39\u4ecb --><\/p>\n<div style=\"background: linear-gradient(135deg, #00796b 0%, #4db6ac 100%); border-radius: 16px; padding: 35px 30px; margin: 30px 0; color: white; text-align: center; box-shadow: 0 4px 20px rgba(0, 121, 107, 0.25);\">\n<p style=\"margin: 0 0 5px 0; font-size: 0.85em; letter-spacing: 4px; opacity: 0.9;\">GORYOKAI GROUP<\/p>\n<h3 style=\"margin: 0 0 8px 0; font-size: 1.9em; color: white; font-weight: bold;\">\u7af9\u5185\u5185\u79d1\u5c0f\u5150\u79d1\u533b\u9662<\/h3>\n<p style=\"margin: 0 0 20px 0; font-size: 0.95em; opacity: 0.9;\">\u533b\u7642\u6cd5\u4eba\u793e\u56e3 \u4e94\u826f\u4f1a<\/p>\n<p><!-- \u8a3a\u7642\u79d1\u76ee\u30bf\u30b0 --><\/p>\n<div style=\"display: flex; flex-wrap: wrap; justify-content: center; gap: 8px; margin-bottom: 25px;\">\n<span style=\"background: rgba(255,255,255,0.2); border: 1px solid rgba(255,255,255,0.5); border-radius: 20px; padding: 6px 14px; font-size: 0.85em;\">\u5185\u79d1<\/span><br \/>\n<span style=\"background: rgba(255,255,255,0.2); border: 1px solid rgba(255,255,255,0.5); border-radius: 20px; padding: 6px 14px; font-size: 0.85em;\">\u5c0f\u5150\u79d1<\/span><br \/>\n<span style=\"background: rgba(255,255,255,0.2); border: 1px solid rgba(255,255,255,0.5); border-radius: 20px; padding: 6px 14px; font-size: 0.85em;\">\u7cd6\u5c3f\u75c5\u5185\u79d1<\/span><br \/>\n<span style=\"background: rgba(255,255,255,0.2); border: 1px solid rgba(255,255,255,0.5); border-radius: 20px; padding: 6px 14px; font-size: 0.85em;\">\u4ee3\u8b1d\u5185\u79d1<\/span><br \/>\n<span style=\"background: rgba(255,255,255,0.2); border: 1px solid rgba(255,255,255,0.5); border-radius: 20px; padding: 6px 14px; font-size: 0.85em;\">\u30a2\u30ec\u30eb\u30ae\u30fc\u79d1<\/span><br \/>\n<span style=\"background: rgba(255,255,255,0.2); border: 1px solid rgba(255,255,255,0.5); border-radius: 20px; padding: 6px 14px; font-size: 0.85em;\">\u76ae\u819a\u79d1<\/span><br \/>\n<span style=\"background: rgba(255,255,255,0.2); border: 1px solid rgba(255,255,255,0.5); border-radius: 20px; padding: 6px 14px; font-size: 0.85em;\">\u751f\u6d3b\u7fd2\u6163\u75c5<\/span><br \/>\n<span style=\"background: rgba(255,255,255,0.2); border: 1px solid rgba(255,255,255,0.5); border-radius: 20px; padding: 6px 14px; font-size: 0.85em;\">\u8a2a\u554f\u8a3a\u7642<\/span><br \/>\n<span style=\"background: rgba(255,255,255,0.2); border: 1px solid rgba(255,255,255,0.5); border-radius: 20px; padding: 6px 14px; font-size: 0.85em;\">\u5fc3\u7642\u5185\u79d1<\/span><br \/>\n<span style=\"background: rgba(255,255,255,0.2); border: 1px solid rgba(255,255,255,0.5); border-radius: 20px; padding: 6px 14px; font-size: 0.85em;\">\u5065\u5eb7\u8a3a\u65ad<\/span>\n<\/div>\n<p><!-- \u571f\u66dc\u5348\u524d\u8a3a\u7642\u30d0\u30c3\u30b8 --><\/p>\n<div style=\"display: inline-block; background: rgba(255,255,255,0.25); border: 2px solid white; border-radius: 25px; padding: 8px 20px; font-weight: bold; font-size: 0.95em;\">\n\u571f\u66dc\u5348\u524d\u3082\u8a3a\u7642\n<\/div>\n<\/div>\n<p><!-- \u8a3a\u7642\u6642\u9593\u8868 --><\/p>\n<div style=\"background: white; border: 1px solid #e0e0e0; border-radius: 12px; padding: 20px; margin: 0 0 25px 0; box-shadow: 0 2px 8px rgba(0,0,0,0.05);\">\n<p style=\"text-align: center; font-weight: bold; color: #00796b; margin: 0 0 15px 0; font-size: 1.05em;\">\u8a3a\u7642\u6642\u9593<\/p>\n<table style=\"width: 100%; border-collapse: collapse; text-align: center; font-size: 0.9em;\">\n<tr style=\"background: #e0f2f1;\">\n<th style=\"padding: 8px; border: 1px solid #b2dfdb;\"><\/th>\n<th style=\"padding: 8px; border: 1px solid #b2dfdb;\">\u6708<\/th>\n<th style=\"padding: 8px; border: 1px solid #b2dfdb;\">\u706b<\/th>\n<th style=\"padding: 8px; border: 1px solid #b2dfdb;\">\u6c34<\/th>\n<th style=\"padding: 8px; border: 1px solid #b2dfdb;\">\u6728<\/th>\n<th style=\"padding: 8px; border: 1px solid #b2dfdb;\">\u91d1<\/th>\n<th style=\"padding: 8px; border: 1px solid #b2dfdb; color: #1565c0;\">\u571f<\/th>\n<th style=\"padding: 8px; border: 1px solid #b2dfdb; color: #c62828;\">\u65e5\u795d<\/th>\n<\/tr>\n<tr>\n<td style=\"padding: 8px; border: 1px solid #e0e0e0; font-weight: bold;\">\u5348\u524d<br \/><span style=\"font-size: 0.8em; color: #888;\">9:00-12:00<\/span><\/td>\n<td style=\"padding: 8px; border: 1px solid #e0e0e0; color: #00796b; font-weight: bold; font-size: 1.2em;\">\u25cb<\/td>\n<td style=\"padding: 8px; border: 1px solid #e0e0e0; color: #00796b; font-weight: bold; font-size: 1.2em;\">\u25cb<\/td>\n<td style=\"padding: 8px; border: 1px solid #e0e0e0; color: #00796b; font-weight: bold; font-size: 1.2em;\">\u25cb<\/td>\n<td style=\"padding: 8px; border: 1px solid #e0e0e0; color: #00796b; font-weight: bold; font-size: 1.2em;\">\u25cb<\/td>\n<td style=\"padding: 8px; border: 1px solid #e0e0e0; color: #00796b; font-weight: bold; font-size: 1.2em;\">\u25cb<\/td>\n<td style=\"padding: 8px; border: 1px solid #e0e0e0; color: #00796b; font-weight: bold; font-size: 1.2em;\">\u25cb<\/td>\n<td style=\"padding: 8px; border: 1px solid #e0e0e0; color: #c62828; font-weight: bold;\">\u4f11<\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 8px; border: 1px solid #e0e0e0; font-weight: bold;\">\u5348\u5f8c<br \/><span style=\"font-size: 0.8em; color: #888;\">15:30-19:00<\/span><\/td>\n<td style=\"padding: 8px; border: 1px solid #e0e0e0; color: #00796b; font-weight: bold; font-size: 1.2em;\">\u25cb<\/td>\n<td style=\"padding: 8px; border: 1px solid #e0e0e0; color: #00796b; font-weight: bold; font-size: 1.2em;\">\u25cb<\/td>\n<td style=\"padding: 8px; border: 1px solid #e0e0e0; color: #00796b; font-weight: bold; font-size: 1.2em;\">\u25cb<\/td>\n<td style=\"padding: 8px; border: 1px solid #e0e0e0; color: #00796b; font-weight: bold; font-size: 1.2em;\">\u25cb<\/td>\n<td style=\"padding: 8px; border: 1px solid #e0e0e0; color: #00796b; font-weight: bold; font-size: 1.2em;\">\u25cb<\/td>\n<td style=\"padding: 8px; border: 1px solid #e0e0e0; color: #c62828; font-weight: bold;\">\u4f11<\/td>\n<td style=\"padding: 8px; border: 1px solid #e0e0e0; color: #c62828; font-weight: bold;\">\u4f11<\/td>\n<\/tr>\n<\/table>\n<p style=\"text-align: center; margin: 10px 0 0 0; font-size: 0.85em; color: #888;\">\n\u3012145-0072 \u6771\u4eac\u90fd\u5927\u7530\u533a\u7530\u5712\u8abf\u5e03\u672c\u753a40-12 \u30b3\u30f3\u30c9\u7530\u5712\u8abf\u5e03\uff12\u968e<br \/>\n\u4f11\u8a3a\u65e5\uff1a\u571f\u66dc\u5348\u5f8c\u30fb\u65e5\u66dc\u30fb\u795d\u65e5\n<\/p>\n<\/div>\n<p><!-- 4\u30ab\u30fc\u30c9\u4e88\u7d04\u30bb\u30af\u30b7\u30e7\u30f3 --><\/p>\n<div style=\"display: flex; flex-wrap: wrap; gap: 15px; justify-content: center;\">\n<p><!-- WEB\u4e88\u7d04 --><\/p>\n<div style=\"flex: 1; min-width: 220px; max-width: 280px; background: white; border-radius: 12px; padding: 20px; text-align: center; box-shadow: 0 2px 8px rgba(0,0,0,0.08);\">\n<div style=\"background: #00796b; color: white; width: 50px; height: 50px; border-radius: 50%; display: flex; align-items: center; justify-content: center; margin: 0 auto 12px; font-size: 1.3em; font-weight: bold;\">\u4e88<\/div>\n<p style=\"margin: 0 0 8px 0; font-weight: bold; color: #00796b; font-size: 1.1em;\">WEB\u4e88\u7d04<\/p>\n<p style=\"margin: 0 0 12px 0; color: #666; font-size: 0.9em;\">24\u6642\u9593\u3044\u3064\u3067\u3082<br \/>\u7c21\u5358\u306b\u3054\u4e88\u7d04\u3044\u305f\u3060\u3051\u307e\u3059<\/p>\n<p><a href=\"https:\/\/clinics-app.com\/clinic\/5e01b71c9e974d40c8a4c361\/exclusive_reservation\" target=\"_blank\" rel=\"noopener\" style=\"display: inline-block; background: #00796b; color: white; text-decoration: none; padding: 10px 25px; border-radius: 25px; font-weight: bold; font-size: 0.95em;\">\u4e88\u7d04\u3059\u308b \u2192<\/a>\n<\/div>\n<p><!-- WEB\u554f\u8a3a --><\/p>\n<div style=\"flex: 1; min-width: 220px; max-width: 280px; background: white; border-radius: 12px; padding: 20px; text-align: center; box-shadow: 0 2px 8px rgba(0,0,0,0.08);\">\n<div style=\"background: #1565c0; color: white; width: 50px; height: 50px; border-radius: 50%; display: flex; align-items: center; justify-content: center; margin: 0 auto 12px; font-size: 1.3em; font-weight: bold;\">\u554f<\/div>\n<p style=\"margin: 0 0 8px 0; font-weight: bold; color: #1565c0; font-size: 1.1em;\">WEB\u554f\u8a3a<\/p>\n<p style=\"margin: 0 0 12px 0; color: #666; font-size: 0.9em;\">\u4e8b\u524d\u306b\u3054\u5165\u529b\u3044\u305f\u3060\u304f\u3068<br \/>\u9662\u5185\u3067\u306e\u5f85\u3061\u6642\u9593\u304c\u77ed\u7e2e\u3055\u308c\u307e\u3059<\/p>\n<p><a href=\"https:\/\/clinics-questionnaire.medley.life\/clinic\/639022194dc5ab531c90e7e8\" target=\"_blank\" rel=\"noopener\" style=\"display: inline-block; background: #1565c0; color: white; text-decoration: none; padding: 10px 25px; border-radius: 25px; font-weight: bold; font-size: 0.95em;\">\u554f\u8a3a\u3092\u5165\u529b \u2192<\/a>\n<\/div>\n<p><!-- LINE --><\/p>\n<div style=\"flex: 1; min-width: 220px; max-width: 280px; background: white; border-radius: 12px; padding: 20px; text-align: center; box-shadow: 0 2px 8px rgba(0,0,0,0.08);\">\n<div style=\"background: #00B900; color: white; width: 50px; height: 50px; border-radius: 50%; display: flex; align-items: center; justify-content: center; margin: 0 auto 12px; font-size: 1.1em; font-weight: bold;\">LINE<\/div>\n<p style=\"margin: 0 0 8px 0; font-weight: bold; color: #00B900; font-size: 1.1em;\">LINE\u516c\u5f0f<\/p>\n<p style=\"margin: 0 0 12px 0; color: #666; font-size: 0.9em;\">\u304a\u77e5\u3089\u305b\u30fb\u5065\u5eb7\u60c5\u5831\u3092<br \/>\u5b9a\u671f\u7684\u306b\u304a\u5c4a\u3051\u3057\u307e\u3059<\/p>\n<p><a href=\"https:\/\/lin.ee\/lvrd7tl\" target=\"_blank\" rel=\"noopener\" style=\"display: inline-block; background: #00B900; color: white; text-decoration: none; padding: 10px 25px; border-radius: 25px; font-weight: bold; font-size: 0.95em;\">LINE\u767b\u9332\u3059\u308b \u2192<\/a>\n<\/div>\n<p><!-- \u96fb\u8a71 --><\/p>\n<div style=\"flex: 1; min-width: 220px; max-width: 280px; background: white; border-radius: 12px; padding: 20px; text-align: center; box-shadow: 0 2px 8px rgba(0,0,0,0.08);\">\n<div style=\"background: #f57c00; color: white; width: 50px; height: 50px; border-radius: 50%; display: flex; align-items: center; justify-content: center; margin: 0 auto 12px; font-size: 1.3em; font-weight: bold;\">TEL<\/div>\n<p style=\"margin: 0 0 8px 0; font-weight: bold; color: #f57c00; font-size: 1.1em;\">\u304a\u96fb\u8a71<\/p>\n<p style=\"margin: 0 0 12px 0; color: #666; font-size: 0.9em;\">\u3054\u4e0d\u660e\u70b9\u306f\u304a\u6c17\u8efd\u306b<br \/>\u30b9\u30bf\u30c3\u30d5\u304c\u4e01\u5be7\u306b\u5bfe\u5fdc\u3057\u307e\u3059<\/p>\n<p><a href=\"tel:03-3721-5222\" style=\"display: inline-block; background: #f57c00; color: white; text-decoration: none; padding: 10px 25px; border-radius: 25px; font-weight: bold; font-size: 0.95em;\">03-3721-5222<\/a>\n<\/div>\n<\/div>\n<p><!-- \u88dc\u8db3\u60c5\u5831 --><\/p>\n<div style=\"margin-top: 20px; text-align: center;\">\n<p style=\"margin: 0 0 5px 0; color: #555; font-size: 0.9em;\">\u203b\u3054\u4e88\u7d04\u306a\u3057\u3067\u3082\u53d7\u8a3a\u53ef\u80fd\u3067\u3059\u304c\u3001\u3054\u4e88\u7d04\u306e\u65b9\u304c\u512a\u5148\u3068\u306a\u308a\u307e\u3059<\/p>\n<p style=\"margin: 0; color: #555; font-size: 0.85em;\">\u203b\u4e3b\u756a\u53f7\u304c\u7e4b\u304c\u308a\u306b\u304f\u3044\u5834\u5408\uff1a<a href=\"tel:070-9050-5103\" style=\"color: #00796b; font-weight: bold;\">070-9050-5103<\/a>\uff08\u30af\u30ea\u30cb\u30c3\u30af\u5c02\u7528\u643a\u5e2f\uff09<\/p>\n<\/div>\n<\/div>\n<p><\/body><br \/>\n<\/html><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u521d\u7248 2025\u5e744\u670817\u65e5 \uff0f \u6700\u7d42\u66f4\u65b0 2026\u5e742\u670820\u65e5\uff5c\u7af9\u5185\u5185\u79d1\u5c0f\u5150\u79d1\u533b\u9662 \u9662\u9577 \u4e94\u85e4\u826f\u5c06 2025\u5e744\u670814\u65e5\u3001\u5927\u76f8\u64b2\u306e\u529b\u58eb\u30fb\u82e5\u6238\u685c\uff08\u308f\u304b\u3068\u3056\u304f\u3089\uff09\u525b\u3055\u3093\u304c\u3001\u5916\u9670\u90e8\u58ca\u6b7b\u6027\u7b4b\u819c\u708e\uff08Fournier\u58ca\u75bd\uff1a\u30d5\u30eb\u30cb\u30a8\u3048&#8230;<\/p>\n","protected":false},"author":2,"featured_media":6723,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[908,907,909],"class_list":["post-6340","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-takeuchi-internal-medicine-and-pediatrics","tag-908","tag-907","tag-909","wpcat-1-id"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.takeuchi-iin.jp\/blog\/wp-json\/wp\/v2\/posts\/6340","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.takeuchi-iin.jp\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.takeuchi-iin.jp\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.takeuchi-iin.jp\/blog\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.takeuchi-iin.jp\/blog\/wp-json\/wp\/v2\/comments?post=6340"}],"version-history":[{"count":3,"href":"https:\/\/www.takeuchi-iin.jp\/blog\/wp-json\/wp\/v2\/posts\/6340\/revisions"}],"predecessor-version":[{"id":6743,"href":"https:\/\/www.takeuchi-iin.jp\/blog\/wp-json\/wp\/v2\/posts\/6340\/revisions\/6743"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.takeuchi-iin.jp\/blog\/wp-json\/wp\/v2\/media\/6723"}],"wp:attachment":[{"href":"https:\/\/www.takeuchi-iin.jp\/blog\/wp-json\/wp\/v2\/media?parent=6340"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.takeuchi-iin.jp\/blog\/wp-json\/wp\/v2\/categories?post=6340"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.takeuchi-iin.jp\/blog\/wp-json\/wp\/v2\/tags?post=6340"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}