{"id":5660,"date":"2024-06-01T11:44:36","date_gmt":"2024-06-01T02:44:36","guid":{"rendered":"https:\/\/www.takeuchi-iin.jp\/blog\/?p=5660"},"modified":"2024-06-15T19:01:21","modified_gmt":"2024-06-15T10:01:21","slug":"%e5%b9%b9%e7%b4%b0%e8%83%9e%e5%9f%b9%e9%a4%8a%e4%b8%8a%e6%b8%85%e6%b6%b2%e3%82%a8%e3%82%af%e3%82%bd%e3%82%bd%e3%83%bc%e3%83%a0%e7%82%b9%e6%bb%b4%e3%81%8c%e9%96%8b%e5%a7%8b%e3%81%84%e3%81%9f%e3%81%97","status":"publish","type":"post","link":"https:\/\/www.takeuchi-iin.jp\/blog\/%e5%b9%b9%e7%b4%b0%e8%83%9e%e5%9f%b9%e9%a4%8a%e4%b8%8a%e6%b8%85%e6%b6%b2%e3%82%a8%e3%82%af%e3%82%bd%e3%82%bd%e3%83%bc%e3%83%a0%e7%82%b9%e6%bb%b4%e3%81%8c%e9%96%8b%e5%a7%8b%e3%81%84%e3%81%9f%e3%81%97\/","title":{"rendered":"\u6b6f\u9ac4\u5e79\u7d30\u80de\u57f9\u990a\u4e0a\u6e05\u6db2\uff08\u30a8\u30af\u30bd\u30bd\u30fc\u30e0\u70b9\u6ef4\uff09\u304c\u958b\u59cb\u3044\u305f\u3057\u307e\u3059\uff01"},"content":{"rendered":"\n
\"\"<\/figure>\n\n\n\n
\"\"<\/figure>\n\n\n\n
\"\"<\/figure>\n\n\n\n
\"\"


\u3010\u5e79\u7d30\u80de\u57f9\u990a\u4e0a\u6e05\u6db2\uff08\u30a8\u30af\u30bd\u30bd\u30fc\u30e0\u70b9\u6ef4<\/strong>\uff09\u3011<\/figcaption><\/figure>\n\n\n\n

2024\u5e746\u67081\u65e5(\u571f)\uff5e\u5f53\u9662\u306b\u3066\u5e79\u7d30\u80de\u57f9\u990a\u4e0a\u6e05\u6db2\uff08\u30a8\u30af\u30bd\u30bd\u30fc\u30e0\u70b9\u6ef4\uff09\u304c\u884c\u3048\u308b\u3088\u3046\u306b\u306a\u308a\u307e\u3057\u305f\u3002\u4e8b\u524d\u306b\u8aac\u660e\u306a\u3069\u5fc5\u8981\u3068\u306a\u308a\u307e\u3059\u306e\u3067\u3001\u307e\u305a\u306f\u4e94\u85e4\u826f\u5c06\u30fb\u9662\u9577\u306e\u5916\u6765\u62c5\u5f53\u6642\u306b\u304a\u8d8a\u3057\u3044\u305f\u3060\u304f\u3088\u3046\u306b\u304a\u9858\u3044\u3044\u81f4\u3057\u307e\u3059\u3002

Q\uff1b
\u5e79\u7d30\u80de\u57f9\u990a\u4e0a\u6e05\u6db2<\/strong>\u3068\u306f\u4f55\u304b\uff1f\u305d\u308c\u306b\u306f\u30a8\u30af\u30bd\u30bd\u30fc\u30e0\u3082\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u3001\u6210\u9577\u56e0\u5b50\u306a\u3069\u3082\u542b\u307e\u308c\u3066\u3044\u308b\u306e\u304b\uff1f\u307b\u304b\u306b\u542b\u307e\u308c\u3066\u3044\u308b\u6210\u5206\u306f\uff1f<\/p>\n\n\n\n

A\uff1b
\u5e79\u7d30\u80de\u57f9\u990a\u4e0a\u6e05\u6db2\uff08conditioned medium\u3001\u30b3\u30f3\u30c7\u30a3\u30b7\u30e7\u30f3\u30c9\u30fb\u30df\u30c7\u30a3\u30a2\u30e0\uff09<\/strong>\u306b\u306f\u30a8\u30af\u30bd\u30bd\u30fc\u30e0<\/strong>\u3001\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u3001\u6210\u9577\u56e0\u5b50\u306e\u4ed6\u306b\u3082\u591a\u304f\u306e\u6709\u52b9\u6210\u5206\u304c\u542b\u307e\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u6210\u5206\u306f\u518d\u751f\u533b\u7642\u3084\u7d44\u7e54\u5de5\u5b66\u3067\u5229\u7528\u3055\u308c\u308b\u3053\u3068\u304c\u591a\u304f\u3001\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u3082\u306e\u304c\u542b\u307e\u308c\u307e\u3059\uff1a<\/p>\n\n\n\n

    \n
  1. \u30a8\u30af\u30bd\u30bd\u30fc\u30e0<\/strong>\uff1a\u7d30\u80de\u9593\u901a\u4fe1\u306b\u4f7f\u7528\u3055\u308c\u308b\u5c0f\u3055\u306a\u819c\u306b\u5305\u307e\u308c\u305f\u5c0f\u80de\u3067\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u3001\u30ea\u30dc\u6838\u9178\uff08RNA\uff09\u3001\u30ea\u30dd\u30bd\u30fc\u30e0\u306a\u3069\u3092\u904b\u642c\u3057\u307e\u3059\u3002<\/li>\n\n\n\n
  2. \u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\uff1a\u514d\u75ab\u53cd\u5fdc\u306e\u8abf\u7bc0\u3084\u708e\u75c7\u5fdc\u7b54\u306b\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3059\u30bf\u30f3\u30d1\u30af\u8cea\u3067\u3059\u3002<\/li>\n\n\n\n
  3. \u6210\u9577\u56e0\u5b50<\/strong>\uff1a\u7d30\u80de\u306e\u5897\u6b96\u3001\u5206\u5316\u3001\u751f\u5b58\u3092\u4fc3\u9032\u3059\u308b\u30bf\u30f3\u30d1\u30af\u8cea\u3067\u3001\u7d44\u7e54\u4fee\u5fa9\u3084\u518d\u751f\u306b\u4e0d\u53ef\u6b20\u3067\u3059\u3002<\/li>\n<\/ol>\n\n\n\n

    \u52a0\u3048\u3066\u3001\u4ee5\u4e0b\u306e\u6210\u5206\u3082\u542b\u307e\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\uff1a<\/p>\n\n\n\n

      \n
    1. \u30b1\u30e2\u30ab\u30a4\u30f3\uff1a\u7279\u5b9a\u306e\u7d30\u80de\u30bf\u30a4\u30d7\u3092\u5f15\u304d\u5bc4\u305b\u308b\u80fd\u529b\u3092\u6301\u3064\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u306e\u4e00\u7a2e\u3067\u3001\u7d44\u7e54\u4fee\u5fa9\u3084\u514d\u75ab\u5fdc\u7b54\u306b\u304a\u3044\u3066\u7d30\u80de\u79fb\u52d5\u3092\u4fc3\u9032\u3057\u307e\u3059\u3002<\/li>\n\n\n\n
    2. \u30a8\u30af\u30b9\u30c8\u30e9\u30bb\u30eb\u30e9\u30fc\u30d9\u30b7\u30af\u30eb\uff1a\u30a8\u30af\u30bd\u30bd\u30fc\u30e0\u3068\u4f3c\u3066\u3044\u307e\u3059\u304c\u3001\u30b5\u30a4\u30ba\u3084\u8d77\u6e90\u304c\u7570\u306a\u308b\u3053\u3068\u304c\u3042\u308a\u3001\u7d30\u80de\u5916\u30de\u30c8\u30ea\u30c3\u30af\u30b9\u6210\u5206\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u3001\u8102\u8cea\u3001\u6838\u9178\u306a\u3069\u3092\u542b\u307f\u307e\u3059\u3002<\/li>\n\n\n\n
    3. \u6838\u9178\uff1amRNA\u3084microRNA\u306a\u3069\u306e\u30ea\u30dc\u6838\u9178\u304c\u542b\u307e\u308c\u3001\u3053\u308c\u3089\u306f\u907a\u4f1d\u60c5\u5831\u306e\u4f1d\u9054\u3084\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u8abf\u7bc0\u306b\u95a2\u4e0e\u3057\u307e\u3059\u3002<\/li>\n<\/ol>\n\n\n\n

      \u3053\u308c\u3089\u306e\u6210\u5206\u306f\u3001\u75c5\u6c17\u306e\u6cbb\u7642\u3084\u640d\u50b7\u3057\u305f\u7d44\u7e54\u306e\u4fee\u5fa9\u3068\u518d\u751f\u306b\u304a\u3044\u3066\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3059\u305f\u3081\u3001\u518d\u751f\u533b\u7642\u306e\u5206\u91ce\u3067\u306e\u7814\u7a76\u3068\u5fdc\u7528\u304c\u9032\u3081\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u7279\u306b\u7d30\u80de\u30d5\u30ea\u30fc\u306e\u6cbb\u7642\u6cd5\u3068\u3057\u3066\u3001\u3053\u308c\u3089\u306e\u6210\u5206\u304c\u542b\u307e\u308c\u308b\u30b3\u30f3\u30c7\u30a3\u30b7\u30e7\u30f3\u30c9\u30fb\u30df\u30c7\u30a3\u30a2\u30e0\u306e\u4f7f\u7528\u306f\u3001\u76f4\u63a5\u7684\u306a\u7d30\u80de\u79fb\u690d\u306e\u4ee3\u66ff\u3068\u3057\u3066\u6709\u671b\u8996\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n

      \uff1d\uff1d\uff1d\uff1d\uff1d\uff1d\uff1d
      \u3010\u57f9\u990a\u4e0a\u6e05<\/strong>\u3068\u306f\u306a\u306b\u304b\u3011
      \u3000\u7d30\u80de\u306f\u3001\u3055\u307e\u3056\u307e\u306a\u30e1\u30c3\u30bb\u30fc\u30b8\u3092\u767a\u3057\u3066\u4e92\u3044\u306b\u60c5\u5831\u4ea4\u63db\u3057\u3066\u3044\u307e\u3059\u3002\u7d30\u80de\u540c\u58eb\u3067\u5897\u6b96\u306e\u30b9\u30d4\u30fc\u30c9\u3084\u5206\u5316\u306e\u7a0b\u5ea6\u306a\u3069\u306e\u751f\u4f53\u6a5f\u80fd\u3092\u8abf\u6574\u3057\u3042\u3046\u306e\u3067\u3059\u3002\u3053\u306e\u3088\u3046\u306a\u30e1\u30c3\u30bb\u30fc\u30b8\u3092\u62c5\u3046\u306e\u304c\u4fe1\u53f7\u5206\u5b50(signaling molecule)\u3068\u547c\u3070\u308c\u308b\u7269\u8cea\u3067\u3059\u3002\u4fe1\u53f7\u5206\u5b50\u306f\u5206\u5b50\u91cf3\u4e07\u7a0b\u5ea6\u306e\u305f\u3093\u3071\u304f\u8cea\u304b\u3089\u306a\u308b\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u3084\u6210\u9577\u56e0\u5b50\u306a\u3069\u3067\u69cb\u6210\u3055\u308c\u3066\u3044\u307e\u3059\u306e\u3067\u3001\u751f\u7406\u6d3b\u6027\u7269\u8cea(bioactive substance)\u3068\u3082\u3088\u3070\u308c\u308b\u3053\u3068\u3082\u3042\u308a\u307e\u3059\u3002
      \u3000\u307e\u305f\u4fe1\u53f7\u5206\u5b50\u3084\u751f\u7406\u6d3b\u6027\u7269\u8cea\u306f\u3001\u57f9\u990a\u6db2\u306e\u306a\u304b\u306b\u6eb6\u3051\u3066\u3044\u307e\u3059\u306e\u3067\u53ef\u6eb6\u6027\u56e0\u5b50(soluble factor)\u3068\u547c\u3076\u3053\u3068\u3082\u3042\u308a\u307e\u3059\u3002\u547c\u3073\u540d\u306f\u9055\u3044\u307e\u3059\u304c\u610f\u5473\u306f\u307f\u306a\u540c\u3058\u306a\u306e\u3067\u6df7\u4e71\u3057\u306a\u3044\u3088\u3046\u306b\u3001\u3053\u3053\u304b\u3089\u306f\u751f\u7406\u6d3b\u6027\u7269\u8cea\u306b\u7d71\u4e00\u3057\u307e\u3057\u3087\u3046\u3002
      \u3000\u7d30\u80de\u306e\u4f5c\u308b\u751f\u7406\u6d3b\u6027\u7269\u8cea\u306f\u6570\u5343\u7a2e\u985e\u306b\u3082\u53ca\u3073\u3001\u591a\u5f69\u306a\u751f\u7269\u5b66\u7684\u52b9\u679c\u3092\u6301\u3063\u3066\u3044\u307e\u3059\u304c\u3001\u3059\u3079\u3066\u57f9\u990a\u6db2\u306e\u306a\u304b\u306b\u84c4\u7a4d\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u57f9\u990a\u6db2\u306e\u306a\u304b\u304b\u3089\u3001\u7d30\u80de\u3084\u7d30\u80de\u306e\u6b8b\u9ab8\u3001\u4ee3\u8b1d\u7269\u8cea\u3084\u8001\u5ec3\u7269\u3092\u3068\u308a\u306e\u305e\u304d\u751f\u7406\u6d3b\u6027\u7269\u8cea\u3060\u3051\u306b\u3057\u305f\u3082\u306e\u304c\u300c\u57f9\u990a\u4e0a\u6e05\u300d(conditioned medium,supernatant\u306a\u3069)<\/strong>\u3068\u3088\u3070\u308c\u308b\u3082\u306e\u3067\u3059\u3002\u3064\u307e\u308a\u57f9\u990a\u4e0a\u6e05\u3068\u306f\u7d30\u80de\u306e\u3064\u304f\u308b\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u306e\u8907\u5408\u4f53\u3067\u3042\u308a\u3001\u3053\u308c\u3089\u306e\u751f\u7406\u6d3b\u6027\u7269\u8cea\u3092\u533b\u7642\u306b\u5fdc\u7528\u3059\u308b\u306e\u304c\u300c\u57f9\u990a\u4e0a\u6e05<\/strong>\u6cbb\u7642\u300d\u306a\u306e\u3067\u3059\u3002
      <\/p>\n\n\n\n

      \u30a8\u30af\u30bd\u30bd\u30fc\u30e0\u70b9\u6ef4\u3067\u3001NMN\u70b9\u6ef4\u3068\u540c\u69d8\u306b\u6700\u8fd1\u3067\u6709\u540d\u306b\u306a\u3063\u3066\u304a\u308a\u307e\u3059\u304c\u3001\u5b9f\u306f\u5e79\u7d30\u80de\u57f9\u990a\u4e0a\u6e05\u6db2<\/strong>\u306b\u306f\u30a8\u30af\u30bd\u30bd\u30fc\u30e0\u3060\u3051\u3067\u306a\u304f\u3001\u6210\u9577\u56e0\u5b50\u3001\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u3001\u30b1\u30e2\u30ab\u30a4\u30f3\u3082<\/strong>\u542b\u307e\u308c\u3066\u3044\u308b\u306e\u3067\u3059\u3002\u5b89\u5168\u6027\u304c\u9ad8\u304f\u3001\u6210\u9577\u56e0\u5b50\u3092\u8c4a\u5bcc\u306b\u542b\u3093\u3060\u6b6f\u9ac4\u5e79\u7d30\u80de\u57f9\u990a\u4e0a\u6e05\u6db2\u3092\u63d0\u4f9b\u3044\u305f\u3057\u307e\u3059\u3002<\/p>\n\n\n\n


      \u3010\u5b89\u5168\u3001\u5b89\u5fc3\u306e\u78ba\u4fdd\u3011<\/strong><\/p>\n\n\n\n

      \u5f53\u9662\u306e\u5e79\u7d30\u80de\u57f9\u990a\u4e0a\u6e05\u6db2<\/strong>\u306f\u3001\u30c9\u30ca\u30fc\u304c\u660e\u78ba\u3067\u3057\u3063\u304b\u308a\u3068\u540c\u610f\u3055\u308c\u3066\u304a\u308a\u3001\u30c8\u30ec\u30fc\u30b5\u30d3\u30ea\u30c6\u30a3\u306f\u78ba\u4fdd\u3055\u308c\u3066\u307e\u3059\u3002
      \u3010\u30c9\u30ca\u30fc\u304c\u660e\u78ba\u3067\u3042\u308b\u3011<\/strong>
      \u4eba\u3092\u5bfe\u8c61\u3068\u3059\u308b\u751f\u547d\u79d1\u5b66\u30fb\u533b\u5b66\u7cfb\u7814\u7a76\u3092\u884c\u3046\u305f\u3081\u306b\u5fc5\u8981\u306a\u5be9\u67fb\u3092\u884c\u3046\u502b\u7406\u59d4\u54e1\u4f1a\u3067\u5be9\u67fb\u3092\u884c\u3063\u3066\u304a\u308a\u3001\u9069\u5207\u306a\u30d7\u30ed\u30bb\u30b9\u3067\u629c\u6b6f\u3001\u6b6f\u9ac4\u7d44\u7e54\u63a1\u53d6\u3092\u884c\u3063\u3066\u3044\u308b\u3002

      \u3010\u7d30\u80de\u53d7\u3051\u5165\u308c\u6642\u306e\u691c\u67fb\u30fb\u4e0a\u6e05\u6db2\u306e\u51fa\u8377\u6642\u306e\u691c\u67fb<\/strong>\u3011
      ◼\u539a\u751f\u52b4\u50cd\u7701\u306e\u751f\u7269\u7531\u6765\u539f\u6599\u57fa\u6e96\u5b89\u5168\u6027\u8a66\u9a13\u3092\u30af\u30ea\u30a2
      ◼\u7121\u83cc\u8a66\u9a13
      ◼\u30a8\u30f3\u30c9\u30c8\u30ad\u30b7\u30f3\u8a66\u9a13\/\u30de\u30a4\u30b3\u30d7\u30e9\u30ba\u30de\u8a66\u9a13
      ◼\u30a6\u30a4\u30eb\u30b9\u5426\u5b9a\u8a66\u9a13
      \uff08HBs\u6297\u539f\u30fb\u6297\u4f53\u3001HBc\u6297\u4f53\u3001HTLV-I\u6297\u4f53(CLIA)\u3001HIV\u6297\u539f
      \u6297\u4f53\u3001\u6885\u6bd2(PRP\/TPHA))
      ◼\u7121\u7d30\u80de\u8a3a\u691c\u67fb
      <\/p>\n\n\n\n

      \u8840\u7ba1\u5185\u3078\u6295\u4e0e\u3092\u884c\u3046\u3053\u3068\u3067\u300c\u5168\u8eab\u306e\u30a8\u30a4\u30b8\u30f3\u30b0\u52b9\u679c\u300d\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\uff01<\/p>\n\n\n\n

      \u2713\u30b3\u30e9\u30fc\u30b2\u30f3\u306e\u751f\u6210\u3092\u4fc3\u9032<\/strong>
      \u2713\u7d30\u80de\u306e\u6d3b\u6027\u5316<\/strong>
      \u2713\u82e5\u8fd4\u308a\u52b9\u679c<\/strong>
      \u2713\u75b2\u52b4\u56de\u5fa9<\/strong>
      \u2713\u6bdb\u9aea\u306e\u518d\u751f\uff08AGA\u3001FAGA\u306b\u3082\u52b9\u679c\u3042\u308a\uff09<\/strong><\/p>\n\n\n\n

      \u306a\u3069\u306a\u3069\u3001\u69d8\u3005\u306a\u52b9\u679c\u304c\u3054\u3056\u3044\u307e\u3059\u3002<\/p>\n\n\n\n

      \"\"<\/figure>\n\n\n\n
      \"\"
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      \"\"
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      \"\"
      \u3010\u30a8\u30af\u30bd\u30bd\u30fc\u30e0\u00d7\u30a8\u30af\u30b9\u30c8\u30ed\u30dd\u30fc\u30b7\u30e7\u30f3\uff08\u30b1\u30a2\u30b7\u30b9S\uff09\u306e\u6599\u91d1\u3011
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      \u80cc\u4e2d\u4e0b\u90e8\uff11\u56de\u65bd\u8853\u300166,000\u5186<\/figcaption><\/figure>\n\n\n\n

      \u3054\u4e0d\u660e\u70b9\u3084\u3054\u8cea\u554f\u7b49\u3054\u3056\u3044\u307e\u3057\u305f\u3089\u304a\u6c17\u8efd\u306b\u304a\u554f\u3044\u5408\u308f\u305b\u304f\u3060\u3055\u3044\u3002<\/p>\n\n\n\n

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      \u3012145-0072 \u6771\u4eac\u90fd\u5927\u7530\u533a\u7530\u5712\u8abf\u5e03\u672c\u753a40-12-201
      \u7af9\u5185\u5185\u79d1\u5c0f\u5150\u79d1\u533b\u9662\u3000\uff08\u6771\u6025\u6771\u6a2a\u7dda\u591a\u6469\u5ddd\u99c5\u5f92\u6b695\u5206\uff09
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      <\/p>\n\n\n\n

      <\/p>\n\n\n\n

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