{"id":4268,"date":"2026-05-04T00:24:50","date_gmt":"2026-05-03T15:24:50","guid":{"rendered":"https:\/\/www.takeuchi-iin.jp\/blog\/?p=4268"},"modified":"2026-05-21T23:16:25","modified_gmt":"2026-05-21T14:16:25","slug":"4268-2","status":"publish","type":"post","link":"https:\/\/www.takeuchi-iin.jp\/blog\/4268-2\/","title":{"rendered":"\u3010\u533b\u5e2b\u5fb9\u5e95\u89e3\u8aac\u3011GLP-1\uff0fGIP\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u306e\u65b0\u6642\u4ee3\uff5c\u90311\u56de\u6ce8\u5c04 \u30aa\u30bc\u30f3\u30d4\u30c3\u30af\uff08\u30bb\u30de\u30b0\u30eb\u30c1\u30c9\uff09\u00d7\u30de\u30f3\u30b8\u30e3\u30ed\u30fb\u30bc\u30c3\u30d7\u30d0\u30a6\u30f3\u30c9\uff08\u30c1\u30eb\u30bc\u30d1\u30c1\u30c9\uff09\u306e\u6700\u65b0\u533b\u5b66\u7684\u30a8\u30d3\u30c7\u30f3\u30b9\u3010\u7530\u5712\u8abf\u5e03\u3011"},"content":{"rendered":"

\u7686\u3055\u307e\u3001\u3053\u3093\u306b\u3061\u306f\u3002\u7af9\u5185\u5185\u79d1\u5c0f\u5150\u79d1\u533b\u9662 \u9662\u9577\u306e\u4e94\u85e4\u826f\u5c06\u3067\u3059\u3002<\/p>\n

\u300c2\u578b\u7cd6\u5c3f\u75c5\u306e\u8840\u7cd6\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u304c\u601d\u3046\u3088\u3046\u306b\u4e0b\u304c\u3089\u306a\u3044\u300d\u300cBMI 27\u3092\u8d85\u3048\u3066\u5065\u8a3a\u3067\u80a5\u6e80\u75c7\u3068\u6307\u6458\u3055\u308c\u305f\u300d\u300c\u81ea\u8cbbGLP-1\u30c0\u30a4\u30a8\u30c3\u30c8\u306e\u5e83\u544a\u3092\u898b\u308b\u304c\u3001\u533b\u5b66\u7684\u306b\u5927\u4e08\u592b\u306a\u306e\u304b\u300d\u2014\u2014\u80a5\u6e80\u75c7\u30682\u578b\u7cd6\u5c3f\u75c5\u306f\u3001\u3044\u307e\u3084\u98df\u6b32\u30db\u30eb\u30e2\u30f3\u3068\u81b5\u5cf6\u30db\u30eb\u30e2\u30f3\u306e\u4e21\u65b9\u3092\u6a19\u7684\u306b\u3059\u308b\u90311\u56de\u6ce8\u5c04<\/strong>\u306e\u6642\u4ee3\u306b\u5165\u308a\u307e\u3057\u305f\u3002GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u30fbGIP\/GLP-1\u30c7\u30e5\u30a2\u30eb\u30a2\u30b4\u30cb\u30b9\u30c8\u306f\u3001\u904e\u53bb50\u5e74\u306e\u3042\u3089\u3086\u308b\u6297\u80a5\u6e80\u85ac\u30fb\u8840\u7cd6\u964d\u4e0b\u85ac\u3092\u4e0a\u56de\u308b\u30a8\u30d3\u30c7\u30f3\u30b9\u3092\u84c4\u7a4d\u3057\u30012026\u5e74\u73fe\u5728\u3001\u7cd6\u5c3f\u75c5\u30fb\u80a5\u6e80\u75c7\u30fb\u5fc3\u8840\u7ba1\u75be\u60a3\u30fb\u6162\u6027\u814e\u81d3\u75c5\u30fb\u7761\u7720\u6642\u7121\u547c\u5438\u306e\u4fdd\u967a\u8a3a\u7642\u306e\u4e3b\u5f79<\/strong>\u3068\u3057\u3066\u4f4d\u7f6e\u3065\u3051\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u672c\u8a18\u4e8b\u3067\u306f\u3001\u7cd6\u5c3f\u75c5\u5185\u79d1\u30fb\u4ee3\u8b1d\u5185\u79d1\u3092\u5c02\u9580\u3068\u3059\u308b\u9662\u9577\u304c\u3001\u30aa\u30bc\u30f3\u30d4\u30c3\u30af\u00ae\uff08\u30bb\u30de\u30b0\u30eb\u30c1\u30c9\uff09\u30fb\u30a6\u30b4\u30fc\u30d3\u00ae\uff08\u30bb\u30de\u30b0\u30eb\u30c1\u30c9\u9ad8\u7528\u91cf\uff09\u30fb\u30de\u30f3\u30b8\u30e3\u30ed\u00ae\uff08\u30c1\u30eb\u30bc\u30d1\u30c1\u30c9\uff09\u30fb\u30bc\u30c3\u30d7\u30d0\u30a6\u30f3\u30c9\u00ae\uff08\u30c1\u30eb\u30bc\u30d1\u30c1\u30c9\uff0f2025\u5e744\u670811\u65e5\u56fd\u5185\u767a\u58f2\uff09\u30fb\u30ea\u30d9\u30eb\u30b5\u30b9\u00ae\uff08\u7d4c\u53e3\u30bb\u30de\u30b0\u30eb\u30c1\u30c9\uff09<\/strong>\u306e\u4f5c\u7528\u6a5f\u5e8f\u3068\u6700\u65b0\u30a8\u30d3\u30c7\u30f3\u30b9\u3001PMDA\u304a\u3088\u3073\u6700\u9069\u4f7f\u7528\u63a8\u9032\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u306b\u57fa\u3065\u304f\u56fd\u5185\u51e6\u65b9\u30eb\u30fc\u30eb\u3001\u65e5\u672c\u4eba\u7279\u6709\u306eSURMOUNT-J\u8a66\u9a13\u30c7\u30fc\u30bf\u307e\u3067\u3092\u5fb9\u5e95\u89e3\u8aac\u3044\u305f\u3057\u307e\u3059\u3002<\/p>\n

\u3042\u308f\u305b\u3066\u3001\u7cd6\u5c3f\u75c5\u6cbb\u7642\u306e\u6700\u524d\u7dda\uff08\u30e1\u30c8\u30db\u30eb\u30df\u30f3\u30fbSGLT2\u30fbCGM\u500b\u5225\u5316\uff0b\u6297\u8001\u5316\u306e\u6700\u65b0\u30a8\u30d3\u30c7\u30f3\u30b9\uff09<\/a>\u3084\u30e1\u30bf\u30dc\u304b\u3089\u7cd6\u5c3f\u75c5\u3078\uff5c2024\u5e74\u65b0\u57fa\u6e96\u30fbsd-LDL\u30fb\u96a0\u308c\u30e1\u30bf\u30dc<\/a>\u306e\u59c9\u59b9\u8a18\u4e8b\u3082\u305c\u3072\u3054\u53c2\u7167\u304f\u3060\u3055\u3044\u3002<\/p>\n

\n

\u76ee\u6b21<\/p>\n

    \n
  1. GLP-1\u3068GIP\u2014\u2014\u300c\u8178\u304c\u8133\u3068\u81b5\u5cf6\u3092\u52d5\u304b\u3059\u300d\u30a4\u30f3\u30af\u30ec\u30c1\u30f3\u9769\u547d<\/a><\/li>\n
  2. \u56fd\u5185\u627f\u8a8d\u88fd\u5264\u306e\u6574\u7406\uff082026\u5e745\u6708\u6642\u70b9\u30fbPMDA\u78ba\u8a8d\uff09<\/a><\/li>\n
  3. \u4f5c\u7528\u6a5f\u5e8f\uff1a6\u3064\u306e\u30bf\u30fc\u30b2\u30c3\u30c8\u306b\u540c\u6642\u306b\u30a2\u30d7\u30ed\u30fc\u30c1\u3059\u308b\u85ac\u5264<\/a><\/li>\n
  4. \u4f53\u91cd\u6e1b\u5c11\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u2014\u2014STEP\u30fbSURMOUNT\u30fbSURMOUNT-J\u8a66\u9a13<\/a><\/li>\n
  5. \u5fc3\u8840\u7ba1\u30fb\u814e\u30fb\u809d\u30fb\u547c\u5438\u5668\u3078\u306e\u6ce2\u53ca\u52b9\u679c\uff08SELECT\u30fbFLOW\u30fbSUSTAIN\u30fbSURMOUNT-OSA\uff09<\/a><\/li>\n
  6. \u65e5\u672c\u306b\u304a\u3051\u308b\u51e6\u65b9\u306e\u5b9f\u969b\u2014\u2014\u9069\u5fdc\u30fb\u7528\u91cf\u6f38\u5897\u30fb\u6700\u9069\u4f7f\u7528\u63a8\u9032\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3<\/a><\/li>\n
  7. \u526f\u4f5c\u7528\u30fb\u7981\u5fcc\u30fb\u5468\u8853\u671f\u4f11\u85ac\u30fb\u85ac\u7269\u76f8\u4e92\u4f5c\u7528<\/a><\/li>\n
  8. \u30aa\u30f3\u30e9\u30a4\u30f3\u51e6\u65b9\u30fb\u500b\u4eba\u8f38\u5165\u30bb\u30de\u30b0\u30eb\u30c1\u30c9\u306e\u5371\u967a\u6027<\/a><\/li>\n
  9. \u98df\u4e8b\u7642\u6cd5\u30fb\u904b\u52d5\u7642\u6cd5\u3068\u306e\u4f75\u7528\u304c\u6210\u529f\u306e\u9375\uff08\u9662\u9577\u8457\u66f8\u306e\u3054\u6848\u5185\uff09<\/a><\/li>\n
  10. \u5f53\u9662\u3067\u306e\u51e6\u65b9\u30d5\u30ed\u30fc\u30fb\u4e94\u826f\u4f1a\u30b0\u30eb\u30fc\u30d7\u5185\u9023\u643a<\/a><\/li>\n
  11. \u95a2\u9023\u8a18\u4e8b\u30fb\u53c2\u8003\u6587\u732e<\/a><\/li>\n<\/ol>\n<\/div>\n

    GLP-1\u3068GIP\u2014\u2014\u300c\u8178\u304c\u8133\u3068\u81b5\u5cf6\u3092\u52d5\u304b\u3059\u300d\u30a4\u30f3\u30af\u30ec\u30c1\u30f3\u9769\u547d<\/h2>\n

    \u98df\u4e8b\u3092\u6442\u308b\u3068\u3001\u5c0f\u8178\u306eL\u7d30\u80de\u304b\u3089GLP-1\uff08\u30b0\u30eb\u30ab\u30b4\u30f3\u69d8\u30da\u30d7\u30c1\u30c9-1\uff09<\/strong>\u3001K\u7d30\u80de\u304b\u3089GIP\uff08\u30b0\u30eb\u30b3\u30fc\u30b9\u4f9d\u5b58\u6027\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u523a\u6fc0\u30dd\u30ea\u30da\u30d7\u30c1\u30c9\uff09<\/strong>\u3068\u3044\u30462\u7a2e\u985e\u306e\u8178\u7ba1\u30db\u30eb\u30e2\u30f3\uff08\u30a4\u30f3\u30af\u30ec\u30c1\u30f3\uff09\u304c\u5206\u6ccc\u3055\u308c\u307e\u3059\u3002\u3053\u308c\u3089\u306f\u8840\u7cd6\u5024\u304c\u9ad8\u3044\u3068\u304d\u306b\u81b5\u03b2\u7d30\u80de\u304b\u3089\u306e\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u3092\u5897\u3084\u3057\u3001\u8840\u7cd6\u5024\u304c\u4f4e\u3044\u3068\u304d\u306b\u306f\u5206\u6ccc\u3092\u6291\u5236\u3059\u308b\u300c\u30b0\u30eb\u30b3\u30fc\u30b9\u4f9d\u5b58\u6027\u300d\u306e\u7279\u6027\u3092\u6301\u3064\u305f\u3081\u3001\u4f4e\u8840\u7cd6\u3092\u8d77\u3053\u3057\u306b\u304f\u3044\u5b89\u5168\u306a\u8840\u7cd6\u8abf\u7bc0\u3092\u62c5\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n

    2\u578b\u7cd6\u5c3f\u75c5\u306e\u60a3\u8005\u3055\u307e\u3067\u306f\u3001\u3053\u306e\u30a4\u30f3\u30af\u30ec\u30c1\u30f3\u4f5c\u7528\u304c\u8457\u3057\u304f\u6e1b\u5f31\u3057\u3066\u3044\u307e\u3059\u3002\u98df\u5f8c\u8840\u7cd6\u306e\u6025\u4e0a\u6607\u30fb\u4f53\u91cd\u5897\u52a0\u30fb\u98df\u5f8c\u306e\u6e80\u8179\u611f\u306e\u4e4f\u3057\u3055\u30fb\u81b5\u03b2\u7d30\u80de\u6a5f\u80fd\u306e\u4f4e\u4e0b\u2014\u2014\u3053\u308c\u3089\u3059\u3079\u3066\u306b\u3001\u5185\u56e0\u6027GLP-1\uff0fGIP\u306e\u4e0d\u8db3\u304c\u6df1\u304f\u95a2\u4e0e\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u3001\u8fd1\u5e74\u306e\u4ee3\u8b1d\u5185\u5206\u6ccc\u5b66\u306e\u7814\u7a76\u3067\u660e\u3089\u304b\u306b\u306a\u308a\u307e\u3057\u305f\u3002<\/p>\n

    GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac<\/strong>\u306f\u4eba\u5de5\u7684\u306bGLP-1\u53d7\u5bb9\u4f53\u3092\u6d3b\u6027\u5316\u3059\u308b\u85ac\u5264\u3001\u30c1\u30eb\u30bc\u30d1\u30c1\u30c9<\/strong>\u306fGIP\u53d7\u5bb9\u4f53\u30fbGLP-1\u53d7\u5bb9\u4f53\u306e\u4e21\u65b9\u306b\u4f5c\u52d5\u3059\u308b\u30c7\u30e5\u30a2\u30eb\u30a2\u30b4\u30cb\u30b9\u30c8\u3067\u3059\u3002\u30d2\u30c8\u5929\u7136\u306eGLP-1\u306f\u8840\u4e2d\u534a\u6e1b\u671f\u304c\u308f\u305a\u304b1\u301c2\u5206\u3067\u3059\u304c\u3001\u88fd\u5264\u5de5\u5b66\u306b\u3088\u308a\u5206\u89e3\u9175\u7d20DPP-4\u304b\u3089\u4fdd\u8b77\u3057\u3001\u30a2\u30eb\u30d6\u30df\u30f3\u3068\u7d50\u5408\u3055\u305b\u3066\u9577\u6642\u9593\u4f5c\u7528\u5316\u3059\u308b\u3053\u3068\u3067\u3001\u90311\u56de\u6ce8\u5c04<\/strong>\u3067\u306e\u6cbb\u7642\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3057\u305f\u3002<\/p>\n

    \n

    \u30e1\u30ab\u30cb\u30ba\u30e0\u56f3\u89e3\uff5c\u30a4\u30f3\u30af\u30ec\u30c1\u30f3\u304c\u4f53\u91cd\u3092\u6e1b\u3089\u3059\u6d41\u308c<\/p>\n\n\n\n\n\n\n\n
    \n1<\/text><\/svg>\n<\/td>\n\u8996\u5e8a\u4e0b\u90e8\u306e\u98df\u6b32\u4e2d\u67a2\u306b\u4f5c\u7528<\/strong>\uff1a\u6e80\u8179\u611f\u3092\u5897\u5f37\u3057\u3001\u7a7a\u8179\u611f\u3092\u6291\u5236\u3059\u308b\u3053\u3068\u3067\u81ea\u7136\u306b\u6442\u53d6\u30ab\u30ed\u30ea\u30fc\u3092\u6e1b\u3089\u3059<\/td>\n<\/tr>\n
    \n2<\/text><\/svg>\n<\/td>\n\u80c3\u6392\u51fa\u3092\u9045\u5ef6<\/strong>\uff1a\u80c3\u304b\u3089\u5341\u4e8c\u6307\u8178\u3078\u306e\u98df\u7269\u79fb\u9001\u901f\u5ea6\u3092\u7de9\u3084\u304b\u306b\u3057\u3001\u98df\u5f8c\u8840\u7cd6\u306e\u6025\u4e0a\u6607\u3092\u6291\u3048\u3001\u6e80\u8179\u611f\u3092\u6301\u7d9a\u3055\u305b\u308b<\/td>\n<\/tr>\n
    \n3<\/text><\/svg>\n<\/td>\n\u81b5\u03b2\u7d30\u80de\u3067\u30b0\u30eb\u30b3\u30fc\u30b9\u4f9d\u5b58\u7684\u306b\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u3092\u4fc3\u9032<\/strong>\uff1a\u8840\u7cd6\u304c\u9ad8\u3044\u3068\u304d\u3060\u3051\u50cd\u304f\u305f\u3081\u4f4e\u8840\u7cd6\u30ea\u30b9\u30af\u304c\u6975\u3081\u3066\u4f4e\u3044<\/td>\n<\/tr>\n
    \n4<\/text><\/svg>\n<\/td>\n\u81b5\u03b1\u7d30\u80de\u304b\u3089\u306e\u30b0\u30eb\u30ab\u30b4\u30f3\u5206\u6ccc\u6291\u5236<\/strong>\uff1a\u809d\u81d3\u306e\u7cd6\u65b0\u751f\u3092\u6291\u3048\u3001\u7a7a\u8179\u6642\u8840\u7cd6\u3092\u4e0b\u3052\u308b<\/td>\n<\/tr>\n
    \n5<\/text><\/svg>\n<\/td>\nGIP\u306f\u8102\u80aa\u7d30\u80de\u3067\u8102\u8cea\u4ee3\u8b1d\u3092\u6539\u5584<\/strong>\uff08\u30c1\u30eb\u30bc\u30d1\u30c1\u30c9\u72ec\u81ea\uff09\uff1a\u5185\u81d3\u8102\u80aa\u30fb\u7570\u6240\u6027\u8102\u80aa\u3092\u52b9\u7387\u7684\u306b\u52d5\u54e1\u3057\u3001\u60aa\u5fc3\u526f\u4f5c\u7528\u3092\u7de9\u548c\u3059\u308b\u5f79\u5272\u3082\u62c5\u3046<\/td>\n<\/tr>\n
    \n6<\/text><\/svg>\n<\/td>\n\u4f53\u91cd\u6e1b\u5c11\uff0bHbA1c\u4f4e\u4e0b\uff0b\u5fc3\u8840\u7ba1\u30fb\u814e\u30fb\u809d\u306e\u4fdd\u8b77\u52b9\u679c<\/strong>\u3092\u540c\u6642\u306b\u3082\u305f\u3089\u3059<\/td>\n<\/tr>\n<\/table>\n<\/div>\n

    \u56fd\u5185\u627f\u8a8d\u88fd\u5264\u306e\u6574\u7406\uff082026\u5e745\u6708\u6642\u70b9\u30fbPMDA\u78ba\u8a8d\uff09<\/h2>\n

    \u65e5\u672c\u3067\u627f\u8a8d\u3055\u308c\u3066\u3044\u308bGLP-1\uff0fGIP\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u306f\u3001\u9069\u5fdc\u75be\u60a3\uff082\u578b\u7cd6\u5c3f\u75c5\uff0f\u80a5\u6e80\u75c7\uff09\u3068\u6295\u4e0e\u7d4c\u8def\uff08\u76ae\u4e0b\u6ce8\u5c04\uff0f\u7d4c\u53e3\uff09\u3067\u6574\u7406\u3059\u308b\u3068\u4ee5\u4e0b\u306e\u3088\u3046\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n\n\n\n\n\n\n\n
    \u88fd\u5264\uff08\u4e00\u822c\u540d\uff09<\/th>\n\u6295\u4e0e<\/th>\n\u56fd\u5185\u9069\u5fdc<\/th>\n\u56fd\u5185\u767a\u58f2<\/th>\n<\/tr>\n<\/thead>\n
    \u30aa\u30bc\u30f3\u30d4\u30c3\u30af\u00ae<\/strong>
    \uff08\u30bb\u30de\u30b0\u30eb\u30c1\u30c9\uff09<\/td>\n    		\u90311\u56deSC
    0.25\u21920.5\u21921.0\u21922.0mg<\/td>\n    		2\u578b\u7cd6\u5c3f\u75c5<\/td>\n2020\u5e746\u6708<\/td>\n<\/tr>\n
    \u30a6\u30b4\u30fc\u30d3\u00ae<\/strong>
    \uff08\u30bb\u30de\u30b0\u30eb\u30c1\u30c9\u9ad8\u7528\u91cf\uff09<\/td>\n    		\u90311\u56deSC
    0.25\u21920.5\u21921.0\u21921.7\u21922.4mg<\/td>\n    		\u80a5\u6e80\u75c7<\/span>\uff08\u6761\u4ef6\u4ed8\u304d\u4fdd\u967a\uff09<\/td>\n2024\u5e742\u6708<\/td>\n<\/tr>\n
    \u30de\u30f3\u30b8\u30e3\u30ed\u00ae<\/strong>
    \uff08\u30c1\u30eb\u30bc\u30d1\u30c1\u30c9\u30fbGIP\/GLP-1\uff09<\/td>\n    		\u90311\u56deSC
    2.5\u21925.0\u219210.0\u219215.0mg<\/td>\n    		2\u578b\u7cd6\u5c3f\u75c5<\/td>\n2023\u5e744\u6708<\/td>\n<\/tr>\n
    \u30bc\u30c3\u30d7\u30d0\u30a6\u30f3\u30c9\u00ae<\/strong>
    \uff08\u30c1\u30eb\u30bc\u30d1\u30c1\u30c9\u30fbGIP\/GLP-1\uff09<\/td>\n    		\u90311\u56deSC
    2.5\u21925.0\u219210.0\u219215.0mg<\/td>\n    		\u80a5\u6e80\u75c7<\/span>\uff08\u6761\u4ef6\u4ed8\u304d\u4fdd\u967a\uff09<\/td>\n2025\u5e744\u670811\u65e5<\/strong><\/td>\n<\/tr>\n
    \u30ea\u30d9\u30eb\u30b5\u30b9\u00ae<\/strong>
    \uff08\u7d4c\u53e3\u30bb\u30de\u30b0\u30eb\u30c1\u30c9\uff09<\/td>\n    		\u6bce\u65e5\u7d4c\u53e3
    3\u21927\u219214mg<\/td>\n    		2\u578b\u7cd6\u5c3f\u75c5<\/td>\n2021\u5e742\u6708<\/td>\n<\/tr>\n
    \u30d3\u30af\u30c8\u30fc\u30b6\u00ae<\/strong>
    \uff08\u30ea\u30e9\u30b0\u30eb\u30c1\u30c9\uff09<\/td>\n    		\u6bce\u65e51\u56deSC
    0.3\u21920.6\u21920.9\u21921.8mg<\/td>\n    		2\u578b\u7cd6\u5c3f\u75c5\uff08\u65e7\u6765\u578b\uff09<\/td>\n2010\u5e746\u6708<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n\n
    \n

    \u30dd\u30a4\u30f3\u30c8\uff5c2025\u5e74\u306f\u300c\u65e5\u672c\u306b\u304a\u3051\u308b\u80a5\u6e80\u75c7\u6cbb\u7642\u5143\u5e74\u300d<\/p>\n

    \u2460 \u30a6\u30b4\u30fc\u30d3\u00ae\uff1a<\/strong>2024\u5e742\u6708\u767a\u58f2\u3002GLP-1\u5358\u5264\u3067\u65e5\u672c\u521d\u306e\u80a5\u6e80\u75c7\u9069\u5fdc\u3002<\/p>\n

    \u2461 \u30bc\u30c3\u30d7\u30d0\u30a6\u30f3\u30c9\u00ae\uff1a<\/strong>2024\u5e7412\u6708\u627f\u8a8d\u30012025\u5e744\u670811\u65e5\u767a\u58f2<\/strong>\u3002GIP\/GLP-1\u30c7\u30e5\u30a2\u30eb\u30a2\u30b4\u30cb\u30b9\u30c8\u3068\u3057\u3066\u306f\u65e5\u672c\u521d\u306e\u80a5\u6e80\u75c7\u9069\u5fdc\u85ac\u3002<\/p>\n

    \u2462 \u3044\u305a\u308c\u3082\u539a\u52b4\u7701\u300c\u6700\u9069\u4f7f\u7528\u63a8\u9032\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u300d<\/strong>\u306b\u57fa\u3065\u304d\u3001\u65bd\u8a2d\u57fa\u6e96\u30fb\u533b\u5e2b\u8981\u4ef6\u30fb\u60a3\u8005\u8981\u4ef6\u3092\u6e80\u305f\u3059\u533b\u7642\u6a5f\u95a2\u3067\u306e\u307f\u51e6\u65b9\u53ef\u80fd\u3067\u3059\u3002<\/p>\n<\/td>\n<\/tr>\n<\/table>\n

    \u4f5c\u7528\u6a5f\u5e8f\uff1a6\u3064\u306e\u30bf\u30fc\u30b2\u30c3\u30c8\u306b\u540c\u6642\u306b\u30a2\u30d7\u30ed\u30fc\u30c1\u3059\u308b\u85ac\u5264<\/h2>\n

    \u5f93\u6765\u306e\u7d4c\u53e3\u8840\u7cd6\u964d\u4e0b\u85ac\uff08SU\u85ac\u30fb\u30d3\u30b0\u30a2\u30ca\u30a4\u30c9\u30fb\u03b1-GI\u30fb\u30c1\u30a2\u30be\u30ea\u30b8\u30f3\u30fbDPP-4\u963b\u5bb3\u85ac\u30fbSGLT2\u963b\u5bb3\u85ac\uff09\u306f\u3001\u305d\u308c\u305e\u308c\u300c\u5358\u4e00\u306e\u81d3\u5668\u30fb\u7d4c\u8def\u300d\u3092\u6a19\u7684\u3068\u3059\u308b\u8a2d\u8a08\u3067\u3057\u305f\u3002GLP-1\uff0fGIP\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u306e\u9769\u65b0\u6027\u306f\u30011\u5264\u30676\u3064\u306e\u81d3\u5668\u306b\u540c\u6642\u306b\u4f5c\u7528\u3059\u308b<\/strong>\u3053\u3068\u3067\u3059\u3002<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n
    \u6a19\u7684\u81d3\u5668<\/th>\n\u4f5c\u7528<\/th>\n\u81e8\u5e8a\u7684\u610f\u7fa9<\/th>\n<\/tr>\n<\/thead>\n
    \u8133\uff08\u8996\u5e8a\u4e0b\u90e8\u30fb\u5f8c\u8133\uff09<\/td>\n\u98df\u6b32\u6291\u5236\u30fb\u6e80\u8179\u611f\u5897\u5f37<\/td>\n\u6442\u53d6\u30ab\u30ed\u30ea\u30fc\u6e1b\u5c11\u2192\u4f53\u91cd\u6e1b\u5c11\u306e\u4e3b\u8981\u30e1\u30ab\u30cb\u30ba\u30e0<\/td>\n<\/tr>\n
    \u80c3<\/td>\n\u80c3\u6392\u51fa\u9045\u5ef6<\/td>\n\u98df\u5f8c\u8840\u7cd6\u4e0a\u6607\u6291\u5236\u30fb\u6e80\u8179\u611f\u6301\u7d9a<\/td>\n<\/tr>\n
    \u81b5\u03b2\u7d30\u80de<\/td>\n\u30b0\u30eb\u30b3\u30fc\u30b9\u4f9d\u5b58\u7684\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc<\/td>\n\u98df\u5f8c\u8840\u7cd6\u4f4e\u4e0b\u30fb\u4f4e\u8840\u7cd6\u30ea\u30b9\u30af\u56de\u907f<\/td>\n<\/tr>\n
    \u81b5\u03b1\u7d30\u80de<\/td>\n\u30b0\u30eb\u30ab\u30b4\u30f3\u5206\u6ccc\u6291\u5236<\/td>\n\u7a7a\u8179\u6642\u8840\u7cd6\u4f4e\u4e0b\u30fb\u809d\u7cd6\u65b0\u751f\u6291\u5236<\/td>\n<\/tr>\n
    \u809d\u81d3<\/td>\n\u809d\u8102\u80aa\u4f4e\u4e0b\u30fb\u30a4\u30f3\u30b9\u30ea\u30f3\u611f\u53d7\u6027\u6539\u5584<\/td>\nMASLD\uff08\u65e7NAFLD\uff09\u30fbMASH\uff08\u65e7NASH\uff09\u306e\u6539\u5584<\/td>\n<\/tr>\n
    \u8102\u80aa\u7d44\u7e54<\/td>\n\u5185\u81d3\u8102\u80aa\u6e1b\u5c11\u30fb\u8102\u8cea\u4ee3\u8b1d\u6539\u5584\uff08GIP\u5bc4\u4e0e\uff09<\/td>\n\u4f53\u7d44\u6210\u306e\u8cea\u7684\u6539\u5584\uff08\u30c1\u30eb\u30bc\u30d1\u30c1\u30c9\uff09<\/td>\n<\/tr>\n
    \u5fc3\u8840\u7ba1\u7cfb<\/td>\n\u8840\u5727\u4f4e\u4e0b\u30fb\u6297\u708e\u75c7\u30fb\u6297\u52d5\u8108\u786c\u5316<\/td>\n\u5fc3\u7b4b\u6897\u585e\u30fb\u8133\u5352\u4e2d\u306e\u767a\u75c7\u4e88\u9632\uff08SELECT\u30fbSUSTAIN-6\uff09<\/td>\n<\/tr>\n
    \u814e\u81d3<\/td>\n\u7cf8\u7403\u4f53\u5185\u5727\u4f4e\u4e0b\u30fb\u6297\u7dda\u7dad\u5316<\/td>\n\u814e\u8907\u5408\u30a8\u30f3\u30c9\u30dd\u30a4\u30f3\u30c8-24%\uff08FLOW\u8a66\u9a13\uff09<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

    \u4f53\u91cd\u6e1b\u5c11\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u2014\u2014STEP\u30fbSURMOUNT\u30fbSURMOUNT-J\u8a66\u9a13<\/h2>\n

    \u4f53\u91cd\u6e1b\u5c11\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u306f\u3001\u4e16\u754c\u306e\u4ee3\u8b1d\u5185\u5206\u6ccc\u5b66\u754c\u306b\u304a\u3044\u3066\u904e\u53bb\u306e\u3042\u3089\u3086\u308b\u6297\u80a5\u6e80\u85ac\u3092\u4e0a\u56de\u308b\u898f\u6a21\u3067\u84c4\u7a4d\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n\n\n\n\n\n\n\n
    \u8a66\u9a13\u540d<\/th>\n\u85ac\u5264\u30fb\u7528\u91cf<\/th>\n\u5bfe\u8c61<\/th>\n\u671f\u9593<\/th>\n\u4f53\u91cd\u6e1b\u5c11\uff08\u30d7\u30e9\u30bb\u30dc\u3068\u306e\u5dee\uff09<\/th>\n<\/tr>\n<\/thead>\n
    STEP-1<\/strong><\/td>\n\u30bb\u30de\u30b0\u30eb\u30c1\u30c9 2.4mg<\/td>\n\u7cd6\u5c3f\u75c5\u306a\u3057\u80a5\u6e80<\/td>\n68\u9031<\/td>\n-14.9%\uff08vs -2.4%\uff09<\/span><\/td>\n<\/tr>\n
    STEP-2<\/strong><\/td>\n\u30bb\u30de\u30b0\u30eb\u30c1\u30c9 2.4mg<\/td>\n2\u578b\u7cd6\u5c3f\u75c5\u5408\u4f75\u80a5\u6e80<\/td>\n68\u9031<\/td>\n-9.6%\uff08vs -3.4%\uff09<\/td>\n<\/tr>\n
    SURMOUNT-1<\/strong><\/td>\n\u30c1\u30eb\u30bc\u30d1\u30c1\u30c9 15mg<\/td>\n\u7cd6\u5c3f\u75c5\u306a\u3057\u80a5\u6e80<\/td>\n72\u9031<\/td>\n-22.5%\uff08vs -2.4%\uff09<\/span><\/td>\n<\/tr>\n
    SURMOUNT-2<\/strong><\/td>\n\u30c1\u30eb\u30bc\u30d1\u30c1\u30c9 15mg<\/td>\n2\u578b\u7cd6\u5c3f\u75c5\u5408\u4f75\u80a5\u6e80<\/td>\n72\u9031<\/td>\n-15.7%\uff08vs -3.3%\uff09<\/td>\n<\/tr>\n
    SURMOUNT-J<\/strong>\uff08\u65e5\u672c\u4eba\uff09<\/td>\n\u30c1\u30eb\u30bc\u30d1\u30c1\u30c9 10mg \/ 15mg<\/td>\n\u65e5\u672c\u4eba\u80a5\u6e80\u75c7\uff08\u7cd6\u5c3f\u75c5\u306a\u3057\uff09<\/td>\n72\u9031<\/td>\n-22.4% \/ -22.1%\uff08vs -0.3%\uff09<\/span><\/td>\n<\/tr>\n
    SURMOUNT-5<\/strong><\/td>\n\u30c1\u30eb\u30bc\u30d1\u30c1\u30c9 vs \u30bb\u30de\u30b0\u30eb\u30c1\u30c9\u76f4\u63a5\u6bd4\u8f03<\/td>\n\u7cd6\u5c3f\u75c5\u306a\u3057\u80a5\u6e80<\/td>\n72\u9031<\/td>\n\u30c1\u30eb\u30bc\u30d1\u30c1\u30c9\u304c\u30bb\u30de\u30b0\u30eb\u30c1\u30c9\u3092\u4e0a\u56de\u308b<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n\n
    \n

    SURMOUNT-J\u2014\u2014\u65e5\u672c\u4eba\u306b\u3082\u660e\u78ba\u306a\u52b9\u679c\u304c\u78ba\u8a8d\u3055\u308c\u305f<\/p>\n

    \u6b27\u7c73\u4eba\u3068\u65e5\u672c\u4eba\u3067\u306fBMI\u306e\u5206\u5e03\u3084\u4f53\u8102\u80aa\u7387\u304c\u7570\u306a\u308b\u305f\u3081\u3001\u6d77\u5916\u30c7\u30fc\u30bf\u3060\u3051\u3067\u306f\u65e5\u672c\u4eba\u3078\u306e\u9069\u7528\u304c\u4e0d\u78ba\u5b9f\u3067\u3057\u305f\u3002SURMOUNT-J\u306f\u65e5\u672c\u4eba\u80a5\u6e80\u75c7\u60a3\u8005\u3092\u5bfe\u8c61\u3068\u3057\u305f\u7b2c3\u76f8\u8a66\u9a13<\/strong>\u3067\u300172\u9031\u3067\u30c1\u30eb\u30bc\u30d1\u30c1\u30c910mg\u7fa4-22.4%\u300115mg\u7fa4-22.1%<\/strong>\u3068\u3044\u3046\u3001\u4e16\u754c\u898f\u6a21\u8a66\u9a13\uff08SURMOUNT-1\uff09\u3068\u905c\u8272\u306a\u3044\u5287\u7684\u306a\u4f53\u91cd\u6e1b\u5c11\u3092\u78ba\u8a8d\u3057\u307e\u3057\u305f\u3002\u3053\u308c\u306f\u65e5\u672c\u306b\u304a\u3051\u308b\u80a5\u6e80\u75c7\u6cbb\u7642\u30a8\u30d3\u30c7\u30f3\u30b9\u3068\u3057\u3066\u6975\u3081\u3066\u91cd\u8981\u3067\u3059\u3002<\/p>\n

    \u51fa\u5178\uff1aKadowaki T \u3089. Lancet Diabetes Endocrinol.<\/em> 2024.<\/p>\n<\/td>\n<\/tr>\n<\/table>\n

    \u5fc3\u8840\u7ba1\u30fb\u814e\u30fb\u809d\u30fb\u547c\u5438\u5668\u3078\u306e\u6ce2\u53ca\u52b9\u679c\uff08SELECT\u30fbFLOW\u30fbSUSTAIN\u30fbSURMOUNT-OSA\uff09<\/h2>\n

    GLP-1\uff0fGIP\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u306e\u771f\u4fa1\u306f\u3001\u4f53\u91cd\u6e1b\u5c11\u306b\u3068\u3069\u307e\u308a\u307e\u305b\u3093\u3002\u300c\u4f53\u91cd\u3092\u6e1b\u3089\u3057\u305f\u7d50\u679c\u3001\u5fc3\u8840\u7ba1\u30fb\u814e\u30fb\u809d\u30fb\u547c\u5438\u5668\u306e\u30a2\u30a6\u30c8\u30ab\u30e0\u3082\u6539\u5584\u3059\u308b\u300d\u3068\u3044\u3046\u300c\u30e1\u30bf\u30dc\u30ea\u30c3\u30af\u30fb\u30b5\u30fc\u30b8\u30a7\u30ea\u30fc\u985e\u4f3c\u300d\u306e\u52b9\u679c\u304c\u3001\u8907\u6570\u306e\u5927\u898f\u6a21RCT\u3067\u5b9f\u8a3c\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n\n\n\n\n\n\n\n
    \u8a66\u9a13\u540d<\/th>\n\u85ac\u5264<\/th>\n\u4e3b\u8981\u30a8\u30f3\u30c9\u30dd\u30a4\u30f3\u30c8<\/th>\n\u7d50\u679c<\/th>\n<\/tr>\n<\/thead>\n
    SELECT<\/strong>\uff082023\uff09<\/td>\n\u30bb\u30de\u30b0\u30eb\u30c1\u30c9 2.4mg<\/td>\n\u7cd6\u5c3f\u75c5\u306e\u306a\u3044\u80a5\u6e80\u8005\u306e\u4e3b\u8981\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\uff08MACE\uff09<\/td>\n-20%\uff08HR 0.80\uff09<\/span><\/td>\n<\/tr>\n
    SUSTAIN-6<\/strong>\uff082016\uff09<\/td>\n\u30bb\u30de\u30b0\u30eb\u30c1\u30c9 0.5\/1.0mg<\/td>\n2\u578b\u7cd6\u5c3f\u75c5\u306eMACE<\/td>\n-26%\uff08HR 0.74\uff09<\/td>\n<\/tr>\n
    FLOW<\/strong>\uff082024\uff09<\/td>\n\u30bb\u30de\u30b0\u30eb\u30c1\u30c9 1.0mg<\/td>\n2\u578b\u7cd6\u5c3f\u75c5\u5408\u4f75CKD\u306e\u814e\u8907\u5408\u30a8\u30f3\u30c9\u30dd\u30a4\u30f3\u30c8<\/td>\n-24%\uff08HR 0.76\uff09<\/span><\/td>\n<\/tr>\n
    SURMOUNT-OSA<\/strong>\uff082024\uff09<\/td>\n\u30c1\u30eb\u30bc\u30d1\u30c1\u30c9 10\/15mg<\/td>\n\u4e2d\u7b49\u75c7\uff5e\u91cd\u75c7\u9589\u585e\u6027\u7761\u7720\u6642\u7121\u547c\u5438\u306eAHI<\/td>\nAHI -50%\u4ee5\u4e0a<\/span>\uff08CPAP\u4f75\u7528\u7fa4\u3067\u3055\u3089\u306b\u6539\u5584\uff09<\/td>\n<\/tr>\n
    FLOW<\/strong>\u30b5\u30d6\u89e3\u6790<\/td>\n\u30bb\u30de\u30b0\u30eb\u30c1\u30c9<\/td>\n\u5fc3\u4e0d\u5168\u5165\u9662\u30fbMACE\u8907\u5408<\/td>\n\u5fc3\u8840\u7ba1\u6b7b-29%\u3001\u5fc3\u4e0d\u5168\u95a2\u9023\u4e8b\u8c61\u3082\u6709\u610f\u6e1b\u5c11<\/td>\n<\/tr>\n
    ESSENCE<\/strong>\uff082025\uff09<\/td>\n\u30bb\u30de\u30b0\u30eb\u30c1\u30c9 2.4mg<\/td>\nMASH\uff08\u65e7NASH\uff09\u306e\u7d44\u7e54\u5b66\u7684\u6539\u5584<\/td>\n\u7dda\u7dad\u5316\u9032\u884c\u3092\u4f34\u308f\u306a\u3044NASH\u6d88\u9000\u7387\u6709\u610f\u6539\u5584<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n\n
    \n

    \u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u81e8\u5e8a\u7684\u610f\u7fa9<\/p>\n

    \u25a1 \u5fc3\u8840\u7ba1\u75be\u60a3\u306e\u4e8c\u6b21\u4e88\u9632<\/strong>\uff1a\u80a5\u6e80\uff0b\u65e2\u5b58\u5fc3\u8840\u7ba1\u75be\u60a3\u60a3\u8005\u3067MACE\u309220%\u6e1b\u5c11\uff08SELECT\uff09<\/p>\n

    \u25a1 \u7cd6\u5c3f\u75c5\u6027\u814e\u75c7\u306e\u9032\u5c55\u6291\u5236<\/strong>\uff1a\u900f\u6790\u30fb\u814e\u6b7b\u30ea\u30b9\u30af\u309224%\u6e1b\u5c11\uff08FLOW\uff09<\/p>\n

    \u25a1 SAS\uff08\u7761\u7720\u6642\u7121\u547c\u5438\uff09\u306e\u6839\u672c\u6539\u5584<\/strong>\uff1aCPAP\u304b\u3089\u306e\u96e2\u8131\u53ef\u80fd\u6027\u3082\u8996\u91ce\uff08SURMOUNT-OSA\uff09<\/p>\n

    \u25a1 MASH\/MASLD\u306e\u809d\u7dda\u7dad\u5316\u6539\u5584<\/strong>\uff08ESSENCE 2025\uff09<\/p>\n

    \u25a1 \u300c\u80a5\u6e80\u75c7\u306f\u85ac\u3067\u6cbb\u7642\u3067\u304d\u308b\u6162\u6027\u75be\u60a3\u3067\u3042\u308b\u300d\u3068\u3044\u3046\u30d1\u30e9\u30c0\u30a4\u30e0\u8ee2\u63db<\/strong>\u3092\u4e16\u754c\u306e\u533b\u5b66\u754c\u306b\u3082\u305f\u3089\u3057\u305f<\/p>\n<\/td>\n<\/tr>\n<\/table>\n

    \u65e5\u672c\u306b\u304a\u3051\u308b\u51e6\u65b9\u306e\u5b9f\u969b\u2014\u2014\u9069\u5fdc\u30fb\u7528\u91cf\u6f38\u5897\u30fb\u6700\u9069\u4f7f\u7528\u63a8\u9032\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3<\/h2>\n

    2\u578b\u7cd6\u5c3f\u75c5\uff08\u4fdd\u967a\u8a3a\u7642\uff09<\/h3>\n

    \u30aa\u30bc\u30f3\u30d4\u30c3\u30af\u00ae\u30fb\u30de\u30f3\u30b8\u30e3\u30ed\u00ae\u30fb\u30ea\u30d9\u30eb\u30b5\u30b9\u00ae\u30fb\u30d3\u30af\u30c8\u30fc\u30b6\u00ae\u306f\u3001\u3059\u3079\u30662\u578b\u7cd6\u5c3f\u75c5\u306e\u8840\u7cd6\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u6539\u5584\u3092\u76ee\u7684\u3068\u3057\u305f\u4fdd\u967a\u8a3a\u7642\u3068\u3057\u3066\u51e6\u65b9\u3067\u304d\u307e\u3059\u3002\u65e5\u672c\u7cd6\u5c3f\u75c5\u5b66\u4f1a\u300e\u7cd6\u5c3f\u75c5\u6cbb\u7642\u30ac\u30a4\u30c92024-2025\u300f\u3067\u306f\u3001\u80a5\u6e80\u3092\u4f34\u30462\u578b\u7cd6\u5c3f\u75c5\u306e\u7b2c\u4e00\u9078\u629e\u85ac\u306e\u4e00\u3064<\/strong>\u3068\u3057\u3066GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u30fbGIP\/GLP-1\u30c7\u30e5\u30a2\u30eb\u30a2\u30b4\u30cb\u30b9\u30c8\u304c\u660e\u8a18\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

    \u80a5\u6e80\u75c7\uff08\u6761\u4ef6\u4ed8\u304d\u4fdd\u967a\u8a3a\u7642\uff09<\/h3>\n

    \u30a6\u30b4\u30fc\u30d3\u00ae\u30fb\u30bc\u30c3\u30d7\u30d0\u30a6\u30f3\u30c9\u00ae\u306f\u80a5\u6e80\u75c7<\/strong>\u306e\u6cbb\u7642\u85ac\u3068\u3057\u3066\u4fdd\u967a\u9069\u7528\u3055\u308c\u307e\u3059\u304c\u3001\u539a\u52b4\u7701\u300c\u6700\u9069\u4f7f\u7528\u63a8\u9032\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u300d\u306b\u3088\u308a\u53b3\u683c\u306a\u51e6\u65b9\u8981\u4ef6\u304c\u5b9a\u3081\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n\n\n\n\n\n\n
    \u8981\u4ef6\u30ab\u30c6\u30b4\u30ea\u30fc<\/th>\n\u30a6\u30b4\u30fc\u30d3\u00ae\uff0f\u30bc\u30c3\u30d7\u30d0\u30a6\u30f3\u30c9\u00ae\u5171\u901a\u306e\u4fdd\u967a\u8981\u4ef6<\/th>\n<\/tr>\n<\/thead>\n
    BMI<\/td>\nBMI 35kg\/m\u00b2\u4ee5\u4e0a\u3001\u307e\u305f\u306f BMI 27kg\/m\u00b2\u4ee5\u4e0a\uff0b2\u3064\u4ee5\u4e0a\u306e\u80a5\u6e80\u95a2\u9023\u5065\u5eb7\u969c\u5bb3<\/td>\n<\/tr>\n
    \u5408\u4f75\u75c7\uff0827\u301c35\u306e\u5834\u5408\uff09<\/td>\n\u9ad8\u8840\u5727\u30fb\u8102\u8cea\u7570\u5e38\u75c7\u30fb2\u578b\u7cd6\u5c3f\u75c5\u306e\u3044\u305a\u308c\u304b\u3092\u5fc5\u305a1\u3064\u4ee5\u4e0a\u542b\u30802\u75be\u60a3\u4ee5\u4e0a<\/td>\n<\/tr>\n
    \u4e8b\u524d\u4ecb\u5165<\/td>\n\u98df\u4e8b\u7642\u6cd5\u30fb\u904b\u52d5\u7642\u6cd5\u30926\u304b\u6708\u4ee5\u4e0a<\/strong>\u5b9f\u65bd\u3057\u3066\u3082\u52b9\u679c\u4e0d\u5341\u5206<\/td>\n<\/tr>\n
    \u533b\u5e2b\u8981\u4ef6<\/td>\n\u65e5\u672c\u80a5\u6e80\u5b66\u4f1a\u30fb\u65e5\u672c\u7cd6\u5c3f\u75c5\u5b66\u4f1a\u306a\u3069\u6307\u5b9a\u5b66\u4f1a\u306e\u5c02\u9580\u533b\u30fb\u6307\u5c0e\u533b\uff08\u8981\u4ef6\u8a73\u7d30\u306f\u6700\u9069\u4f7f\u7528\u63a8\u9032GL\uff09<\/td>\n<\/tr>\n
    \u65bd\u8a2d\u8981\u4ef6<\/td>\n\u591a\u8077\u7a2e\u30c1\u30fc\u30e0\uff08\u533b\u5e2b\u30fb\u7ba1\u7406\u6804\u990a\u58eb\u30fb\u770b\u8b77\u5e2b\u7b49\uff09\u306b\u3088\u308b\u7d99\u7d9a\u7ba1\u7406\u4f53\u5236<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

    \u7528\u91cf\u6f38\u5897\uff08\u91cd\u8981\u2014\u2014\u526f\u4f5c\u7528\u56de\u907f\u306e\u9375\uff09<\/h3>\n

    GLP-1\uff0fGIP\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u306f\u3001\u6025\u306b\u9ad8\u7528\u91cf\u3067\u958b\u59cb\u3059\u308b\u3068\u60aa\u5fc3\u30fb\u5614\u5410\u306e\u983b\u5ea6\u304c\u5287\u7684\u306b\u5897\u52a0<\/strong>\u3057\u307e\u3059\u3002\u5fc5\u305a\u4f4e\u7528\u91cf\u304b\u3089\u958b\u59cb\u3057\u30014\u9031\u9593\u3054\u3068\u306b\u6bb5\u968e\u7684\u306b\u5897\u91cf\u3057\u307e\u3059\u3002\u4f8b\u3048\u3070\u30a6\u30b4\u30fc\u30d3\u00ae\u3067\u306f0.25mg\u21920.5mg\u21921.0mg\u21921.7mg\u21922.4mg\u3068\u6700\u4f4e16\u9031\u9593\u304b\u3051\u3066\u7dad\u6301\u7528\u91cf\u306b\u5230\u9054\u3057\u307e\u3059\u3002\u30de\u30f3\u30b8\u30e3\u30ed\u00ae\u30fb\u30bc\u30c3\u30d7\u30d0\u30a6\u30f3\u30c9\u00ae\u306f2.5mg\u304b\u30895.0mg\u30784\u9031\u9593\u5f8c\u5897\u91cf\u3001\u4ee5\u964d\u306f4\u9031\u9593\u3054\u3068\u306b\u8a55\u4fa1\u3057\u306a\u304c\u3089\u6700\u592715.0mg\u307e\u3067\u5897\u91cf\u3067\u304d\u307e\u3059\u3002<\/p>\n

    \u526f\u4f5c\u7528\u30fb\u7981\u5fcc\u30fb\u5468\u8853\u671f\u4f11\u85ac\u30fb\u85ac\u7269\u76f8\u4e92\u4f5c\u7528<\/h2>\n

    \u983b\u5ea6\u306e\u9ad8\u3044\u526f\u4f5c\u7528<\/h3>\n

    \u60aa\u5fc3\u30fb\u5614\u5410\u30fb\u4e0b\u75e2\u30fb\u4fbf\u79d8\u30fb\u98df\u6b32\u4e0d\u632f\u304c\u4e2d\u5fc3\u3067\u3001\u3044\u305a\u308c\u3082\u7528\u91cf\u6f38\u5897\u3067\u8efd\u6e1b<\/strong>\u3067\u304d\u307e\u3059\u3002\u6295\u4e0e\u958b\u59cb2\u301c4\u9031\u9593\u306b\u96c6\u4e2d\u3057\u3001\u591a\u304f\u306f\u7d99\u7d9a\u3068\u3068\u3082\u306b\u8010\u6027\u304c\u5f62\u6210\u3055\u308c\u307e\u3059\u3002\u8131\u6c34\u3092\u9632\u3050\u305f\u3081\u3001\u6d88\u5316\u5668\u75c7\u72b6\u304c\u5f37\u3044\u5834\u5408\u306f\u3053\u307e\u3081\u306a\u6c34\u5206\u6442\u53d6\u3068\u4e00\u6642\u7684\u306a\u6e1b\u91cf\u30fb\u6e1b\u901f\u5897\u91cf\u3092\u691c\u8a0e\u3057\u307e\u3059\u3002<\/p>\n

    \u7a00\u306a\u304c\u3089\u91cd\u7be4\u306a\u526f\u4f5c\u7528<\/h3>\n\n\n
    \n

    \u91cd\u8981\uff5c\u91cd\u7be4\u526f\u4f5c\u7528\u3068\u5bfe\u5fdc<\/p>\n

    \u30fb\u6025\u6027\u81b5\u708e<\/strong>\uff1a\u4e0a\u8179\u90e8\u30fb\u80cc\u90e8\u306e\u6301\u7d9a\u6027\u6fc0\u75db\u306f\u76f4\u3061\u306b\u53d7\u8a3a<\/p>\n

    \u30fb\u80c6\u56a2\u708e\u30fb\u80c6\u77f3\u75c7<\/strong>\uff1a\u4f53\u91cd\u6025\u6e1b\u306b\u4f34\u3044\u80c6\u77f3\u5f62\u6210\u30ea\u30b9\u30af\u4e0a\u6607<\/p>\n

    \u30fb\u7cd6\u5c3f\u75c5\u7db2\u819c\u75c7\u306e\u6025\u901f\u60aa\u5316<\/strong>\uff1aHbA1c\u6025\u901f\u4f4e\u4e0b\u6642\u306b\u9032\u5c55\u3059\u308b\u53ef\u80fd\u6027\u3001\u958b\u59cb\u524d\u306b\u773c\u79d1\u8a55\u4fa1\u63a8\u5968<\/p>\n

    \u30fb\u4f4e\u8840\u7cd6<\/strong>\uff1a\u5358\u72ec\u3067\u306f\u7a00\u3002SU\u85ac\u30fb\u30a4\u30f3\u30b9\u30ea\u30f3\u3068\u306e\u4f75\u7528\u6642\u306b\u767a\u73fe<\/p>\n

    \u30fb\u30a4\u30ec\u30a6\u30b9\u69d8\u75c7\u72b6<\/strong>\uff1a\u9ad8\u5ea6\u4fbf\u79d8\u30fb\u8179\u90e8\u81a8\u6e80\u30fb\u5614\u5410\u6301\u7d9a\u2192\u76f4\u3061\u306b\u8a55\u4fa1<\/p>\n<\/td>\n<\/tr>\n<\/table>\n

    \u7981\u5fcc<\/h3>\n

    \u672c\u4eba\u307e\u305f\u306f\u5bb6\u65cf\u6b74\u306b\u7532\u72b6\u817a\u9ac4\u69d8\u764c\uff08MTC\uff09\u30fb\u591a\u767a\u6027\u5185\u5206\u6ccc\u816b\u760d\u75c72\u578b\uff08MEN2\uff09<\/strong>\u304c\u3042\u308b\u65b9\u3001\u7cd6\u5c3f\u75c5\u6027\u30b1\u30c8\u30a2\u30b7\u30c9\u30fc\u30b7\u30b9\u30011\u578b\u7cd6\u5c3f\u75c5\u306e\u5358\u72ec\u6cbb\u7642\u76ee\u7684\u3001\u598a\u5a20\u4e2d\u30fb\u6388\u4e73\u4e2d\u3001\u904e\u654f\u75c7\u65e2\u5f80\u306e\u65b9\u3002<\/p>\n

    \u5468\u8853\u671f\u30fb\u5185\u8996\u93e1\u524d\u306e\u4f11\u85ac\uff08\u6975\u3081\u3066\u91cd\u8981\uff09<\/h3>\n\n\n
    \n

    \u624b\u8853\u30fb\u5168\u8eab\u9ebb\u9154\u30fb\u93ae\u9759\u4e0b\u5185\u8996\u93e1\u306e\u524d\u306f\u4f11\u85ac\u5fc5\u9808<\/p>\n

    \u7c73\u56fd\u9ebb\u9154\u79d1\u5b66\u4f1a\uff08ASA\uff09\u306f2023\u5e74\u3001GLP-1\uff0fGIP\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u4f7f\u7528\u8005\u306e\u80c3\u6392\u51fa\u9045\u5ef6\u306b\u3088\u308b\u8aa4\u56a5\u30ea\u30b9\u30af<\/strong>\u3092\u8b66\u544a\u3057\u3001\u65bd\u8853\u524d\u306e\u4f11\u85ac\u3092\u52e7\u544a\u3057\u307e\u3057\u305f\u3002\u5f53\u9662\u3067\u3082\u4ee5\u4e0b\u3092\u9075\u5b88\u3057\u3066\u3044\u307e\u3059\uff1a<\/p>\n

    \u30fb\u90311\u56de\u6ce8\u5c04\u88fd\u5264\uff1a\u65bd\u8853\u524d1\u9031\u9593\uff08\u6700\u7d42\u6295\u4e0e\u304b\u30897\u65e5\u4ee5\u4e0a\uff09\u306e\u4f11\u85ac<\/strong><\/p>\n

    \u30fb\u7d4c\u53e3\u30bb\u30de\u30b0\u30eb\u30c1\u30c9\uff1a\u65bd\u8853\u524d\u65e5\u304b\u3089\u306e\u4f11\u85ac<\/p>\n

    \u30fb\u5185\u8996\u93e1\uff08\u80c3\u30ab\u30e1\u30e9\u30fb\u5927\u8178\u30ab\u30e1\u30e9\uff09\u3092\u542b\u3080\u93ae\u9759\u51e6\u7f6e\u3067\u3082\u540c\u69d8\u306e\u4f11\u85ac\u304c\u63a8\u5968\u3055\u308c\u307e\u3059<\/p>\n<\/td>\n<\/tr>\n<\/table>\n

    \u85ac\u7269\u76f8\u4e92\u4f5c\u7528<\/h3>\n

    \u80c3\u6392\u51fa\u9045\u5ef6\u4f5c\u7528\u306b\u3088\u308a\u3001\u540c\u6642\u670d\u7528\u3059\u308b\u7d4c\u53e3\u85ac\u306e\u5438\u53ce\u901f\u5ea6\u304c\u5909\u5316<\/strong>\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u30ef\u30eb\u30d5\u30a1\u30ea\u30f3\u30fb\u7d4c\u53e3\u907f\u598a\u85ac\u30fb\u7532\u72b6\u817a\u30db\u30eb\u30e2\u30f3\u85ac\u30fb\u6297\u3066\u3093\u304b\u3093\u85ac\u30fb\u30c6\u30aa\u30d5\u30a3\u30ea\u30f3\u306a\u3069\u3001\u8840\u4e2d\u6fc3\u5ea6\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0\u304c\u5fc5\u8981\u306a\u85ac\u5264\u3092\u4f75\u7528\u3057\u3066\u3044\u308b\u65b9\u306f\u3001\u533b\u5e2b\u30fb\u85ac\u5264\u5e2b\u306b\u3054\u76f8\u8ac7\u304f\u3060\u3055\u3044\u3002\u30a4\u30f3\u30b9\u30ea\u30f3\u30fbSU\u85ac\u4f75\u7528\u6642\u306f\u4f4e\u8840\u7cd6\u4e88\u9632\u306e\u305f\u3081\u3001SU\u85ac\u30fb\u30a4\u30f3\u30b9\u30ea\u30f3\u3092\u6e1b\u91cf\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n

    \u30aa\u30f3\u30e9\u30a4\u30f3\u51e6\u65b9\u30fb\u500b\u4eba\u8f38\u5165\u30bb\u30de\u30b0\u30eb\u30c1\u30c9\u306e\u5371\u967a\u6027<\/h2>\n

    \u300c\u7121\u8a3a\u5bdf\u30aa\u30f3\u30e9\u30a4\u30f3GLP-1\u30c0\u30a4\u30a8\u30c3\u30c8\u300d\u300c\u500b\u4eba\u8f38\u5165\u30bb\u30de\u30b0\u30eb\u30c1\u30c9\u300d\u300c\u7f8e\u5bb9\u30af\u30ea\u30cb\u30c3\u30af\u306e\u5373\u65e5\u51e6\u65b9\u300d\u304c\u5e83\u544a\u3067\u76ee\u7acb\u3063\u3066\u3044\u307e\u3059\u304c\u3001\u533b\u7642\u6a5f\u95a2\u3068\u3057\u3066\u5f37\u304f\u8b66\u9418\u3092\u9cf4\u3089\u3055\u3056\u308b\u3092\u5f97\u307e\u305b\u3093\u3002<\/p>\n\n\n
    \n

    \u91cd\u8981\uff5c\u5b89\u6613\u306a\u81ea\u8cbbGLP-1\u30c0\u30a4\u30a8\u30c3\u30c8\u306e5\u3064\u306e\u5371\u967a<\/p>\n

    \u30fbWHO\u30fbFDA\u304c\u507d\u9020\u30bb\u30de\u30b0\u30eb\u30c1\u30c9\u306e\u4e16\u754c\u7684\u6d41\u901a\u3092\u7e70\u308a\u8fd4\u3057\u8b66\u544a<\/strong>\u3002\u6709\u52b9\u6210\u5206\u91cf\u4e0d\u660e\u3001\u4e0d\u7d14\u7269\u6df7\u5165\u3001\u7121\u52b9\u30fb\u6709\u5bb3\u4e8b\u8c61\u306e\u30ea\u30b9\u30af<\/p>\n

    \u30fb\u6025\u6027\u81b5\u708e\u30fb\u7532\u72b6\u817a\u764c\u30fb\u4f4e\u8840\u7cd6\u306a\u3069\u306e\u91cd\u7be4\u526f\u4f5c\u7528<\/strong>\u306b\u533b\u5e2b\u304c\u5bfe\u5fdc\u3067\u304d\u306a\u3044\uff08\u30d5\u30a9\u30ed\u30fc\u8a3a\u7642\u306a\u3057\uff09<\/p>\n

    \u30fb1\u578b\u7cd6\u5c3f\u75c5\u30fbLADA\u30fb\u81b5\u6027\u7cd6\u5c3f\u75c5<\/strong>\u3092\u898b\u9003\u3057\u305f\u307e\u307e\u8aa4\u3063\u3066\u5c0e\u5165\u3057\u7cd6\u5c3f\u75c5\u30b1\u30c8\u30a2\u30b7\u30c9\u30fc\u30b7\u30b9\u3092\u8d77\u3053\u3059\u5371\u967a<\/p>\n

    \u30fb\u672c\u6765GLP-1\u6cbb\u7642\u3092\u5fc5\u8981\u3068\u3059\u308b2\u578b\u7cd6\u5c3f\u75c5\u30fb\u80a5\u6e80\u75c7\u60a3\u8005<\/strong>\u306e\u6b63\u898f\u4f9b\u7d66\u3092\u903c\u8feb\u3055\u305b\u308b\u793e\u4f1a\u7684\u554f\u984c<\/p>\n

    \u30fb\u5468\u8853\u671f\u4f11\u85ac\u6307\u793a\u3084\u7528\u91cf\u6f38\u5897\u7ba1\u7406<\/strong>\u304c\u9069\u5207\u306b\u884c\u308f\u308c\u306a\u3044<\/p>\n<\/td>\n<\/tr>\n<\/table>\n

    \u5f53\u9662\u3067\u306f\u3001\u300c\u30a4\u30f3\u30bf\u30fc\u30cd\u30c3\u30c8\u8ca9\u58f2\u578bGLP-1\u30c0\u30a4\u30a8\u30c3\u30c8\u300d\u300c\u7121\u8a3a\u5bdf\u30aa\u30f3\u30e9\u30a4\u30f3\u51e6\u65b9\u300d\u300c\u500b\u4eba\u8f38\u5165\u300d\u306f\u63a8\u5968\u3044\u305f\u3057\u307e\u305b\u3093<\/strong>\u3002\u5bfe\u9762\u8a3a\u7642\u3068\u9577\u671f\u7ba1\u7406\u306e\u4e2d\u3067\u3001\u60a3\u8005\u3055\u307e\u306e\u75c5\u614b\uff082\u578b\u7cd6\u5c3f\u75c5\uff0f\u80a5\u6e80\u75c7\uff0f\u30e1\u30bf\u30dc\uff0f\u975e\u9069\u5fdc\uff09\u3092\u6b63\u78ba\u306b\u8a3a\u65ad\u3057\u305f\u3046\u3048\u3067\u3001\u4fdd\u967a\u8a3a\u7642\u307e\u305f\u306f\u533b\u5b66\u7684\u306b\u59a5\u5f53\u306a\u81ea\u8cbb\u8a3a\u7642\u3092\u3054\u63d0\u6848\u3044\u305f\u3057\u307e\u3059\u3002<\/p>\n

    \u98df\u4e8b\u7642\u6cd5\u30fb\u904b\u52d5\u7642\u6cd5\u3068\u306e\u4f75\u7528\u304c\u6210\u529f\u306e\u9375\uff08\u9662\u9577\u8457\u66f8\u306e\u3054\u6848\u5185\uff09<\/h2>\n

    STEP-1\u8a66\u9a13\u30fbSURMOUNT-1\u8a66\u9a13\u30fbSURMOUNT-J\u8a66\u9a13\u306e\u3044\u305a\u308c\u3082\u3001\u300c\u751f\u6d3b\u7fd2\u6163\u4ecb\u5165\u3092\u4f75\u7528\u3057\u305f\u3046\u3048\u3067\u300d<\/strong>\u3068\u3044\u3046\u6761\u4ef6\u4e0b\u3067\u52b9\u679c\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002GLP-1\uff0fGIP\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u306f\u300c\u98f2\u3080\u3060\u3051\u3067\u75e9\u305b\u308b\u9b54\u6cd5\u306e\u85ac\u300d\u3067\u306f\u306a\u304f\u3001\u98df\u4e8b\u7642\u6cd5\u30fb\u904b\u52d5\u7642\u6cd5\u3068\u7d44\u307f\u5408\u308f\u305b\u308b\u3053\u3068\u3067\u521d\u3081\u3066\u30a8\u30d3\u30c7\u30f3\u30b9\u901a\u308a\u306e\u52b9\u679c\u304c\u767a\u63ee\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n
    \n

    \u9662\u9577\u8457\u66f8\uff5c\u300e\u8840\u6db2\u3068\u4f53\u306e\u300c\u3042\u3076\u3089\u300d\u3092\u843d\u3068\u3059\u30b9\u30fc\u30d7\u300f\uff08\u30a2\u30b9\u30b3\u30e0\u30012024\u5e74\uff09<\/p>\n

    \u4e2d\u6027\u8102\u80aa\u30fbLDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u30fb\u5185\u81d3\u8102\u80aa\u304c\u6c17\u306b\u306a\u308b\u65b9\u5411\u3051\u306b\u3001\u7121\u7406\u306a\u304f\u7d9a\u3051\u3089\u308c\u308b1\u65e51\u676f\u306e\u30b9\u30fc\u30d7\u30ec\u30b7\u30d4<\/strong>\u3092\u307e\u3068\u3081\u305f\u4e00\u518a\u3067\u3059\u3002GLP-1\uff0fGIP\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u306b\u3088\u308b\u6cbb\u7642\u3092\u53d7\u3051\u3066\u3044\u308b\u65b9\u306b\u3082\u3001\u85ac\u306e\u52b9\u679c\u3092\u6700\u5927\u5316\u3059\u308b\u305f\u3081\u306e\u98df\u4e8b\u6226\u7565\u3068\u3057\u3066\u5b9f\u8df5\u3057\u3066\u3044\u305f\u3060\u3051\u307e\u3059\u3002<\/p>\n

    \u300c\u30d9\u30b8\u30d5\u30a1\u30fc\u30b9\u30c8<\/a>\u300d\u300c\u98df\u7269\u7e4a\u7dad\u30d5\u30a1\u30fc\u30b9\u30c8\u300d\u300c\u30bf\u30f3\u30d1\u30af\u8cea\u5148\u884c\u300d\u3068\u3044\u3063\u305f\u98df\u4e8b\u306e\u9806\u5e8f\u306e\u5de5\u592b\u304b\u3089\u3001\u5185\u81d3\u8102\u80aa\u3092\u52b9\u7387\u7684\u306b\u6e1b\u3089\u3059\u98df\u6750\u9078\u3073\u307e\u3067\u3001\u533b\u5b66\u7684\u6839\u62e0\u3068\u3068\u3082\u306b\u89e3\u8aac\u3057\u3066\u3044\u307e\u3059\u3002
    \u8a73\u7d30\uff1a    \u300e\u8840\u6db2\u3068\u4f53\u306e\u300c\u3042\u3076\u3089\u300d\u3092\u843d\u3068\u3059\u30b9\u30fc\u30d7\u300f\uff08Amazon\uff09<\/a><\/p>\n<\/td>\n<\/tr>\n<\/table>\n

    \u5f53\u9662\u3067\u306f\u7ba1\u7406\u6804\u990a\u58eb\u306b\u3088\u308b\u300c\u6804\u990a\u6307\u5c0e\u5916\u6765\u300d<\/strong>\u3082\u4f75\u8a2d\u3057\u3066\u304a\u308a\u3001\u7cd6\u5c3f\u75c5\u30fb\u80a5\u6e80\u75c7\u306e\u98df\u4e8b\u7642\u6cd5\u3092\u500b\u5225\u306b\u30b5\u30dd\u30fc\u30c8\u3057\u3066\u3044\u307e\u3059\u3002\u6642\u9593\u6804\u990a\u5b66\uff08\u5915\u98df\u306f\u5bdd\u308b3\u6642\u9593\u524d\u307e\u3067\uff09<\/a>\u3084\u8178\u5185\u30d5\u30ed\u30fc\u30e9\u3068\u514d\u75ab<\/a>\u3068\u3044\u3063\u305f\u751f\u6d3b\u5168\u822c\u306e\u6700\u9069\u5316\u3068\u7d44\u307f\u5408\u308f\u305b\u3066\u3001\u5065\u5eb7\u5bff\u547d\u306e\u5ef6\u4f38\u3092\u4e00\u7dd2\u306b\u3081\u3056\u3057\u307e\u3057\u3087\u3046\u3002<\/p>\n

    \u5f53\u9662\u3067\u306e\u51e6\u65b9\u30d5\u30ed\u30fc\u30fb\u4e94\u826f\u4f1a\u30b0\u30eb\u30fc\u30d7\u5185\u9023\u643a<\/h2>\n\n\n\n\n\n\n\n\n\n\n
    \u30b9\u30c6\u30c3\u30d7<\/th>\n\u5185\u5bb9<\/th>\n<\/tr>\n<\/thead>\n
    \u2460\u521d\u8a3a\u8a55\u4fa1<\/strong><\/td>\n\u554f\u8a3a\u30fb\u63a1\u8840\uff08\u8840\u7cd6\u30fbHbA1c\u30fb\u8102\u8cea\u30fb\u809d\u6a5f\u80fd\u30fb\u814e\u6a5f\u80fd\u30fb\u7532\u72b6\u817a\uff09\u30fb\u8840\u5727\u30fb\u8eab\u4f53\u8a08\u6e2c\u30fb\u65e2\u5f80\u85ac\u306e\u78ba\u8a8d\u30fb\u65e2\u5f80\u6b74\u30fb\u5bb6\u65cf\u6b74\uff08\u7532\u72b6\u817a\u9ac4\u69d8\u764c\u30fbMEN2\u306e\u78ba\u8a8d\uff09<\/td>\n<\/tr>\n
    \u2461\u9069\u5fdc\u5224\u65ad<\/strong><\/td>\n2\u578b\u7cd6\u5c3f\u75c5\uff08\u4fdd\u967a\uff09\uff0f\u80a5\u6e80\u75c7\u30a6\u30b4\u30fc\u30d3\u00ae\u30fb\u30bc\u30c3\u30d7\u30d0\u30a6\u30f3\u30c9\u00ae\uff08\u4fdd\u967a\u6761\u4ef6\u4ed8\u304d\uff09\uff0f\u81ea\u8cbb\u533b\u7642\u75e9\u8eab\u2014\u2014\u60a3\u8005\u3055\u307e\u306e\u75c5\u614b\u3068\u6700\u9069\u4f7f\u7528\u63a8\u9032\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3092\u7167\u5408<\/td>\n<\/tr>\n
    \u2462\u85ac\u5264\u9078\u629e<\/strong><\/td>\n\u75c5\u614b\u30fb\u4f53\u578b\u30fb\u5408\u4f75\u75c7\uff08CKD\u30fb\u5fc3\u8840\u7ba1\u75be\u60a3\u30fb\u8102\u80aa\u809d\u30fbSAS\uff09\u30fb\u6ce8\u5c04\u3078\u306e\u62b5\u6297\u611f\u30fb\u7d4c\u6e08\u7684\u4e8b\u60c5\u3092\u7dcf\u5408\u5224\u65ad<\/td>\n<\/tr>\n
    \u2463\u5c0e\u5165\u30fb\u6307\u5c0e<\/strong><\/td>\n\u4f4e\u7528\u91cf\u304b\u3089\u958b\u59cb\u30fb\u81ea\u5df1\u6ce8\u5c04\u624b\u6280\u6307\u5c0e\u30fb\u526f\u4f5c\u7528\u521d\u671f\u75c7\u72b6\u306e\u8aac\u660e\u30fb\u6804\u990a\u6307\u5c0e\u5916\u6765\u4f75\u7528\u30fb\u751f\u6d3b\u6307\u5c0e<\/td>\n<\/tr>\n
    \u2464\u7d99\u7d9a\u30d5\u30a9\u30ed\u30fc<\/strong><\/td>\n\u67081\u56de\u306e\u8a3a\u5bdf\u30fb\u63a1\u8840\u30fb\u4f53\u91cd\u6e2c\u5b9a\u3002CGM\uff08\u6301\u7d9a\u8840\u7cd6\u30e2\u30cb\u30bf\u30fc\uff09\u4f75\u7528\u3082\u53ef\u80fd<\/td>\n<\/tr>\n
    \u2465\u5408\u4f75\u75c7\u8a55\u4fa1<\/strong><\/td>\n\u5fc3\u8840\u7ba1\u30fb\u814e\u30fb\u809d\u30fb\u773c\u5e95\u30fbSAS\u7b49\u306e\u8a55\u4fa1\u3002\u5fc5\u8981\u6642\u306f\u59c9\u59b9\u9662\u30fb\u4e94\u826f\u4f1a\u30af\u30ea\u30cb\u30c3\u30af\u767d\u91d1\u9ad8\u8f2a<\/strong>\u3068\u9023\u643a\u3057\u3001\u6d88\u5316\u5668\u5185\u8996\u93e1\uff08\u7389\u4e95\u535a\u4fee\u9662\u9577\uff09\u30fb\u4eba\u9593\u30c9\u30c3\u30af\u3067\u3088\u308a\u6df1\u3044\u8a55\u4fa1\u3078<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n\n
    \n

    \u53d7\u8a3a\u524d\u30c1\u30a7\u30c3\u30af\u30ea\u30b9\u30c8<\/p>\n

    \u25a1 \u76f4\u8fd13\u304b\u6708\u306e\u4f53\u91cd\u5909\u5316<\/p>\n

    \u25a1 \u5065\u8a3a\u7d50\u679c\uff08\u63a1\u8840\u30fbBMI\u30fb\u8179\u56f2\uff09<\/p>\n

    \u25a1 \u5185\u670d\u85ac\u30fb\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u306e\u4e00\u89a7<\/p>\n

    \u25a1 \u65e2\u5f80\u6b74\uff08\u81b5\u708e\u30fb\u80c6\u77f3\u30fb\u7cd6\u5c3f\u75c5\u7db2\u819c\u75c7\u30fb\u7532\u72b6\u817a\u75be\u60a3\uff09<\/p>\n

    \u25a1 \u5bb6\u65cf\u6b74\uff08\u7532\u72b6\u817a\u9ac4\u69d8\u764c\u30fbMEN2\u30fb\u5fc3\u7b4b\u6897\u585e\u30fb\u8133\u5352\u4e2d\u30fb\u7cd6\u5c3f\u75c5\uff09<\/p>\n

    \u25a1 \u98df\u4e8b\u30fb\u904b\u52d5\u7fd2\u6163\u306e\u6982\u8981<\/p>\n<\/td>\n<\/tr>\n<\/table>\n\n\n
    \n

    \u4e94\u826f\u4f1a\u30b0\u30eb\u30fc\u30d7\u5185\u306e\u9023\u643a\u2014\u2014\u60a3\u8005\u3055\u307e\u306e\u30e9\u30a4\u30d5\u30b9\u30c6\u30fc\u30b8\u306b\u5408\u308f\u305b\u3066<\/p>\n

    \u533b\u7642\u6cd5\u4eba\u793e\u56e3\u4e94\u826f\u4f1a\u3067\u306f\u3001\u7530\u5712\u8abf\u5e03\u306e\u7af9\u5185\u5185\u79d1\u5c0f\u5150\u79d1\u533b\u9662\uff08\u9662\u9577\uff1a\u4e94\u85e4\u826f\u5c06\uff09<\/strong>\u3068\u6e2f\u533a\u306e\u4e94\u826f\u4f1a\u30af\u30ea\u30cb\u30c3\u30af\u767d\u91d1\u9ad8\u8f2a\uff08\u9662\u9577\uff1a\u7389\u4e95\u535a\u4fee\uff0f4\u5b66\u4f1a\u5c02\u9580\u533b\u30fb\u6307\u5c0e\u533b\uff09<\/strong>\u304c\u9023\u643a\u3057\u3066\u304a\u308a\u307e\u3059\u3002<\/p>\n

    \u7cd6\u5c3f\u75c5\u30fb\u80a5\u6e80\u75c7\u306e\u9577\u671f\u7ba1\u7406\u306b\u304a\u3044\u3066\u306f\u3001\u7530\u5712\u8abf\u5e03\u3067\u65e5\u5e38\u8a3a\u7642\u3068\u90311\u56de\u6ce8\u5c04\u306e\u30d5\u30a9\u30ed\u30fc\u3092\u884c\u3044\u3001\u6d88\u5316\u5668\u5185\u8996\u93e1\uff08\u80c3\u30fb\u5927\u8178\u30ab\u30e1\u30e9\uff09\u30fb\u4eba\u9593\u30c9\u30c3\u30af\u30fb\u8102\u80aa\u809d\u7cbe\u67fb<\/strong>\u306f\u767d\u91d1\u9ad8\u8f2a\u3067\u306e\u5b9f\u65bd\u304c\u53ef\u80fd\u3067\u3059\u3002\u60a3\u8005\u3055\u307e\u306e\u8ee2\u5c45\u3084\u30e9\u30a4\u30d5\u30b9\u30bf\u30a4\u30eb\u306e\u5909\u5316\u306b\u5408\u308f\u305b\u3066\u3001\u540c\u3058\u30b0\u30eb\u30fc\u30d7\u5185\u3067\u7d99\u7d9a\u8a3a\u7642\u304c\u53d7\u3051\u3089\u308c\u308b\u4f53\u5236\u3092\u6574\u3048\u3066\u304a\u308a\u307e\u3059\u3002<\/p>\n<\/td>\n<\/tr>\n<\/table>\n

    \u95a2\u9023\u8a18\u4e8b\u30fb\u53c2\u8003\u6587\u732e<\/h2>\n\n\n
    \n

    \u95a2\u9023\u8a18\u4e8b\uff5c\u7af9\u5185\u5185\u79d1\u5c0f\u5150\u79d1\u533b\u9662\uff08\u7530\u5712\u8abf\u5e03\uff09<\/p>\n\n\n\n\n\n\n
    ▶<\/td>\n\u7cd6\u5c3f\u75c5\u6cbb\u7642\u306e\u6700\u524d\u7dda\uff5c\u30e1\u30c8\u30db\u30eb\u30df\u30f3\u30fbSGLT2\u30fbCGM\u500b\u5225\u5316\uff0b\u6297\u8001\u5316\u306e\u6700\u65b0\u30a8\u30d3\u30c7\u30f3\u30b9<\/a>
    GLP-1\uff0fGIP\u3068\u4e26\u3076\u7cd6\u5c3f\u75c5\u85ac\u306e\u4e3b\u5f79\u3001\u30e1\u30c8\u30db\u30eb\u30df\u30f3\u30fbSGLT2\u963b\u5bb3\u85ac\u306e\u7dcf\u5408\u89e3\u8aac<\/span><\/td>\n<\/tr>\n
    ▶<\/td>\n\u30e1\u30bf\u30dc\u304b\u3089\u7cd6\u5c3f\u75c5\u3078\uff5c2024\u5e74\u65b0\u57fa\u6e96\u30fbsd-LDL\u30fb\u96a0\u308c\u30e1\u30bf\u30dc<\/a>
    \u533b\u7642\u75e9\u8eab\u306e\u4e0a\u6d41\u306b\u3042\u308b\u30e1\u30bf\u30dc\u30ea\u30c3\u30af\u30b7\u30f3\u30c9\u30ed\u30fc\u30e0\u3002\u65e5\u672c\u4eba\u7279\u6709\u306e\u300c\u75e9\u305b\u3066\u3044\u3066\u3082\u30e1\u30bf\u30dc\u300d\u4f53\u8cea<\/span><\/td>\n<\/tr>\n
    ▶<\/td>\n\u4e2d\u6027\u8102\u80aa\u304c\u9ad8\u3044\u3068\u6307\u6458\u3055\u308c\u305f\u65b9\u3078\uff5cWHO\u5206\u985e\u3068\u30e1\u30ab\u30cb\u30ba\u30e0<\/a>
    \u80a5\u6e80\u30fb\u8102\u8cea\u7570\u5e38\u75c7\u306fGLP-1\uff0fGIP\u306e\u9069\u5fdc\u3068\u306a\u308b\u75c5\u614b\u3002\u4e2d\u6027\u8102\u80aa\u9ad8\u5024\u306e\u533b\u5b66\u7684\u77e5\u8b58<\/span><\/td>\n<\/tr>\n
    ▶<\/td>\n\u8840\u7cd6\u5024\u3092\u6025\u4e0a\u6607\u3055\u305b\u306a\u3044\u300c\u30d9\u30b8\u30d5\u30a1\u30fc\u30b9\u30c8\u300d\u306e\u79d1\u5b66<\/a>
    GLP-1\u6cbb\u7642\u3068\u76f8\u4e57\u52b9\u679c\u306e\u3042\u308b\u98df\u4e8b\u9806\u5e8f\u3002\u6804\u990a\u6307\u5c0e\u5916\u6765\u3068\u306e\u9023\u52d5<\/span><\/td>\n<\/tr>\n
    ▶<\/td>\n\u5915\u98df\u306f\u5bdd\u308b3\u6642\u9593\u524d\u307e\u3067\u2014\u2014\u6642\u9593\u6804\u990a\u5b66\u3067\u6574\u3048\u308b\u4ee3\u8b1d\u3068\u7761\u7720<\/a>
    \u4f53\u5185\u6642\u8a08\u3068\u4ee3\u8b1d\u306e\u6700\u9069\u5316\u3002GLP-1\uff0fGIP\u306e\u52b9\u679c\u3092\u6700\u5927\u5316\u3059\u308b\u98df\u4e8b\u30bf\u30a4\u30df\u30f3\u30b0<\/span><\/td>\n<\/tr>\n<\/table>\n<\/td>\n<\/tr>\n<\/table>\n\n\n
    \n

    \u95a2\u9023\u8a18\u4e8b\uff5c\u4e94\u826f\u4f1a\u30af\u30ea\u30cb\u30c3\u30af\u767d\u91d1\u9ad8\u8f2a\uff08\u6e2f\u533a\uff09<\/p>\n\n\n\n
    ▶<\/td>\n\u7cd6\u5c3f\u75c5\u6cbb\u7642\u00d7\u5185\u8996\u93e1\u00d7\u4eba\u9593\u30c9\u30c3\u30af\u3010\u4e94\u826f\u4f1a\u30af\u30ea\u30cb\u30c3\u30af\u767d\u91d1\u9ad8\u8f2a 1F\u3011<\/a>
    \u7389\u4e95\u9662\u9577\uff084\u5b66\u4f1a\u5c02\u9580\u533b\u30fb\u6307\u5c0e\u533b\uff09\u306b\u3088\u308b\u6d88\u5316\u5668\u5185\u8996\u93e1\u3092\u7cd6\u5c3f\u75c5\u7ba1\u7406\u3068\u7d44\u307f\u5408\u308f\u305b\u3066\u63d0\u4f9b<\/span><\/td>\n<\/tr>\n
    ▶<\/td>\nPURE FLOW \u00d7 L-\u30ab\u30eb\u30cb\u30c1\u30f3\u8102\u80aa\u71c3\u713c\u6ce8\u5c04\u3010\u767d\u91d1\u9ad8\u8f2a 2F\u7f8e\u5bb9\u76ae\u819a\u79d1\u3011<\/a>
    GLP-1\u3068\u4f5c\u7528\u6a5f\u5e8f\u306e\u7570\u306a\u308b\u8102\u80aa\u4ee3\u8b1d\u4fc3\u9032\u30a2\u30d7\u30ed\u30fc\u30c1\u3002L-\u30ab\u30eb\u30cb\u30c1\u30f3\u30fb\u03b1\u30ea\u30dd\u9178\u306e\u89e3\u8aac<\/span><\/td>\n<\/tr>\n<\/table>\n<\/td>\n<\/tr>\n<\/table>\n

    \u4e94\u826f\u4f1a\u30b0\u30eb\u30fc\u30d7\u3067\u306f\u3001\u7530\u5712\u8abf\u5e03\u304b\u3089\u767d\u91d1\u9ad8\u8f2a\u307e\u3067\u533b\u5e2b\u304c\u9023\u643a\u3057\u3066\u304a\u308a\u307e\u3059\u3002\u60a3\u8005\u3055\u307e\u306e\u8ee2\u5c45\u3084\u30e9\u30a4\u30d5\u30b9\u30bf\u30a4\u30eb\u306e\u5909\u5316\u306b\u5408\u308f\u305b\u3066\u3001\u540c\u3058\u30b0\u30eb\u30fc\u30d7\u5185\u3067\u7d99\u7d9a\u8a3a\u7642\u304c\u53d7\u3051\u3089\u308c\u308b\u4f53\u5236\u3092\u6574\u3048\u3066\u304a\u308a\u307e\u3059\u3002<\/p>\n

    \u4e3b\u306a\u53c2\u8003\u6587\u732e<\/h3>\n
      \n
    1. Wilding JPH \u3089. Once-Weekly Semaglutide in Adults with Overweight or Obesity (STEP-1). N Engl J Med.<\/em> 2021;384(11):989-1002. PMID: 33567185.<\/li>\n
    2. Davies M \u3089. Semaglutide 2.4 mg once a week in adults with overweight or obesity, and type 2 diabetes (STEP-2). Lancet.<\/em> 2021;397:971-984.<\/li>\n
    3. Jastreboff AM \u3089. Tirzepatide Once Weekly for the Treatment of Obesity (SURMOUNT-1). N Engl J Med.<\/em> 2022;387(3):205-216. PMID: 35658024.<\/li>\n
    4. Garvey WT \u3089. Tirzepatide once weekly for the treatment of obesity in people with type 2 diabetes (SURMOUNT-2). Lancet.<\/em> 2023;402:613-626.<\/li>\n
    5. Kadowaki T \u3089. Tirzepatide for Japanese patients with obesity disease (SURMOUNT-J). Lancet Diabetes Endocrinol.<\/em> 2024.<\/li>\n
    6. Lincoff AM \u3089. Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes (SELECT). N Engl J Med.<\/em> 2023;389(24):2221-2232. PMID: 37952131.<\/li>\n
    7. Marso SP \u3089. Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes (SUSTAIN-6). N Engl J Med.<\/em> 2016;375(19):1834-1844. PMID: 27633186.<\/li>\n
    8. Perkovic V \u3089. Effects of Semaglutide on Chronic Kidney Disease (FLOW). N Engl J Med.<\/em> 2024;391(2):109-121. DOI: 10.1056\/NEJMoa2403347.<\/li>\n
    9. Malhotra A \u3089. Tirzepatide for the Treatment of Obstructive Sleep Apnea and Obesity (SURMOUNT-OSA). N Engl J Med.<\/em> 2024.<\/li>\n
    10. \u539a\u751f\u52b4\u50cd\u7701\u300c\u6700\u9069\u4f7f\u7528\u63a8\u9032\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3000\u30bb\u30de\u30b0\u30eb\u30c1\u30c9\uff08\u907a\u4f1d\u5b50\u7d44\u63db\u3048\uff09\u300d\uff08\u30a6\u30b4\u30fc\u30d3\u00ae\uff09.<\/li>\n
    11. \u539a\u751f\u52b4\u50cd\u7701\u300c\u6700\u9069\u4f7f\u7528\u63a8\u9032\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3000\u30c1\u30eb\u30bc\u30d1\u30c1\u30c9\u300d\uff08\u30bc\u30c3\u30d7\u30d0\u30a6\u30f3\u30c9\u00ae\uff09.<\/li>\n
    12. \u65e5\u672c\u80a5\u6e80\u5b66\u4f1a\u300c\u80a5\u6e80\u75c7\u6cbb\u7642\u85ac\u306e\u5b89\u5168\u30fb\u9069\u6b63\u4f7f\u7528\u306b\u95a2\u3059\u308b\u30b9\u30c6\u30fc\u30c8\u30e1\u30f3\u30c8\u300d\uff082025\u5e744\u670810\u65e5\u6539\u8a02\uff09.<\/li>\n
    13. \u65e5\u672c\u7cd6\u5c3f\u75c5\u5b66\u4f1a\u300e\u7cd6\u5c3f\u75c5\u6cbb\u7642\u30ac\u30a4\u30c92024-2025\u300f\u6587\u5149\u5802, 2024.<\/li>\n
    14. \u65e5\u672c\u80a5\u6e80\u5b66\u4f1a\u300e\u80a5\u6e80\u75c7\u8a3a\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f32022\u300f\u30e9\u30a4\u30d5\u30b5\u30a4\u30a8\u30f3\u30b9\u51fa\u7248, 2022.<\/li>\n
    15. \u4e94\u85e4\u826f\u5c06\u300e\u8840\u6db2\u3068\u4f53\u306e\u300c\u3042\u3076\u3089\u300d\u3092\u843d\u3068\u3059\u30b9\u30fc\u30d7\u300f\u30a2\u30b9\u30b3\u30e0, 2024.<\/li>\n<\/ol>\n

      \u672c\u8a18\u4e8b\u306f\u5b66\u8853\u60c5\u5831\u306e\u63d0\u4f9b\u3092\u76ee\u7684\u3068\u3057\u305f\u3082\u306e\u3067\u3001\u7279\u5b9a\u306e\u52b9\u679c\u3092\u4fdd\u8a3c\u3059\u308b\u3082\u306e\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u500b\u3005\u306e\u51e6\u65b9\u5224\u65ad\u306f\u5bfe\u9762\u8a3a\u7642\u3092\u884c\u3046\u4e3b\u6cbb\u533b\u306e\u7dcf\u5408\u7684\u5224\u65ad\u306b\u57fa\u3065\u304d\u307e\u3059\u3002\u63b2\u8f09\u60c5\u5831\u306f2026\u5e745\u6708\u6642\u70b9\u3067PMDA\u30fb\u539a\u751f\u52b4\u50cd\u7701\u30fb\u5404\u5b66\u4f1a\u516c\u958b\u60c5\u5831\u306b\u57fa\u3065\u304d\u78ba\u8a8d\u3057\u3066\u3044\u307e\u3059\u304c\u3001\u6700\u65b0\u306e\u627f\u8a8d\u72b6\u6cc1\u3084\u6dfb\u4ed8\u6587\u66f8\u6539\u8a02\u306fPMDA\u30a6\u30a7\u30d6\u30b5\u30a4\u30c8\u7b49\u3067\u9069\u5b9c\u3054\u78ba\u8a8d\u304f\u3060\u3055\u3044\u3002<\/p>\n

      <\/p>\n

      \n
      \n
      GORYOKAI GROUP<\/div>\n
      \u7af9\u5185\u5185\u79d1\u5c0f\u5150\u79d1\u533b\u9662<\/div>\n<\/p><\/div>\n
      \n\n\n\n
      \u5185\u79d1<\/td>\n\u5c0f\u5150\u79d1<\/td>\n\u7cd6\u5c3f\u75c5\u5185\u79d1<\/td>\n\u4ee3\u8b1d\u5185\u79d1<\/td>\n\u30a2\u30ec\u30eb\u30ae\u30fc\u79d1<\/td>\n<\/tr>\n
      \u76ae\u819a\u79d1<\/td>\n\u751f\u6d3b\u7fd2\u6163\u75c5<\/td>\n\u8a2a\u554f\u8a3a\u7642<\/td>\n\u5fc3\u7642\u5185\u79d1<\/td>\n\u5065\u5eb7\u8a3a\u65ad<\/td>\n<\/tr>\n<\/table>\n

      \u3012145-0072 \u6771\u4eac\u90fd\u5927\u7530\u533a\u7530\u5712\u8abf\u5e03\u672c\u753a40-12 \u30b3\u30f3\u30c9\u7530\u5712\u8abf\u5e03\uff12\u968e<\/p>\n

      \u6771\u6025\u6771\u6a2a\u7dda\u30fb\u76ee\u9ed2\u7dda\u3000\u591a\u6469\u5ddd\u99c5 \u5f92\u6b695\u5206<\/p>\n

      \u571f\u66dc\u5348\u524d\u3082\u8a3a\u7642<\/div>\n\n\n\n\n\n\n
      \u8a3a\u7642\u6642\u9593<\/th>\n\u6708<\/th>\n\u706b<\/th>\n\u6c34<\/th>\n\u6728<\/th>\n\u91d1<\/th>\n\u571f<\/th>\n\u65e5\u795d<\/th>\n<\/tr>\n<\/thead>\n
      \u5348\u524d
      9:00-12:00<\/td>\n      		\u25cb<\/td>\n\u25cb<\/td>\n\u25cb<\/td>\n\u25cb<\/td>\n\u25cb<\/td>\n\u25cb<\/td>\n\u4f11<\/td>\n<\/tr>\n
      \u5348\u5f8c
      15:30-19:00<\/td>\n      		\u25cb<\/td>\n\u25cb<\/td>\n\u25cb<\/td>\n\u25cb<\/td>\n\u25cb<\/td>\n\u4f11<\/td>\n\u4f11<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n\n
      \n
      \n \"CLINICS\"
      \n WEB\u4e88\u7d04<\/span>
      \n <\/a>\n <\/td>\n      		\n
      \n \"melmo\"
      \n WEB\u554f\u8a3a<\/span>
      \n <\/a>\n <\/td>\n      		\n
      \n <\/svg>
      \n LINE<\/span>
      \n <\/a>\n <\/td>\n      		\n
      \n <\/svg>
      \n TEL<\/span>
      \n <\/a>\n <\/td>\n<\/tr>\n<\/table><\/div>\n<\/div>\n

      \u7af9\u5185\u5185\u79d1\u5c0f\u5150\u79d1\u533b\u9662 \u9662\u9577\u3000\u4e94\u85e4 \u826f\u5c06
      \u65e5\u672c\u6297\u52a0\u9f62\u533b\u5b66\u4f1a\u5c02\u9580\u533b\u30fb\u65e5\u672c\u7cd6\u5c3f\u75c5\u5354\u4f1a\u767b\u9332\u533b\u30fb\u65e5\u672c\u65c5\u884c\u533b\u5b66\u4f1a\u8a8d\u5b9a\u533b<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

      \u7686\u3055\u307e\u3001\u3053\u3093\u306b\u3061\u306f\u3002\u7af9\u5185\u5185\u79d1\u5c0f\u5150\u79d1\u533b\u9662 \u9662\u9577\u306e\u4e94\u85e4\u826f\u5c06\u3067\u3059\u3002 \u300c2\u578b\u7cd6\u5c3f\u75c5\u306e\u8840\u7cd6\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u304c\u601d\u3046\u3088\u3046\u306b\u4e0b\u304c\u3089\u306a\u3044\u300d\u300cBMI 27\u3092\u8d85\u3048\u3066\u5065\u8a3a\u3067\u80a5\u6e80\u75c7\u3068\u6307\u6458\u3055\u308c\u305f\u300d\u300c\u81ea\u8cbbGLP-1\u30c0\u30a4\u30a8\u30c3\u30c8\u306e\u5e83\u544a\u3092\u898b\u308b\u304c\u3001\u533b\u5b66\u7684\u306b\u5927\u4e08\u592b…<\/p>\n","protected":false},"author":2,"featured_media":4286,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1,566,676,4,697,14,21,12,344],"tags":[1023,954,1028,677,1024,1026,1027,1025,779,610,260,1029],"class_list":["post-4268","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-takeuchi-internal-medicine-and-pediatrics","category-566","category-676","category-4","category-697","category-14","category-21","category-12","category-344","tag-gip","tag-glp-1","tag-1028","tag-677","tag-1024","tag-1026","tag-1027","tag-1025","tag-779","tag-610","tag-260","tag-1029","wpcat-1-id","wpcat-566-id","wpcat-676-id","wpcat-4-id","wpcat-697-id","wpcat-14-id","wpcat-21-id","wpcat-12-id","wpcat-344-id"],"aioseo_notices":[],"aioseo_head":"\n\t\t\n\t\n\t\n\t\n\t\n\t\n\t\n\n\t\t